Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0030552 (
paresis
)
5,831
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hexachlorophene
(
HCP
) intoxication in swine was studied as a possible model of
HCP
poisoning in human beings. Swine were topically or orally given
HCP
each day, and observations were made on central nervous system function, hematologic measurements, serum chemical analyses, necropsy, microscopic examination of tissues, and concentrations of
HCP
residues in blood and tissue. Intoxication was observed in orally exposed swine, but the syndrome was not consistently produced in topically exposed swine. Signs and microscopic lesions were all related to dysfunction of the central nervous system, e.g., incoordination,
paresis
, and status spongiosus. Occurrence of signs and lesions, mortality rates, and concentrations of
HCP
residue were positively correlated with the dosage of
HCP
given.
...
PMID:Experimental hexachlorophene intoxication in young swine. 119 Jun 4
