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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

At Flinders Medical Centre in Adelaide, eye surgery under local anaesthesia (peribulbar block) has been carried out in the day ophthalmic surgery unit since 1987. In a subset of 536 patients, 112 patients required additional anaesthesia (supplementary retrobulbar block or regional muscle infiltration) to achieve full ocular paresis, and 10 patients required intraoperative supplementation of anaesthesia because of discomfort. Six patients had their surgery postponed (one had a retrobulbar haemorrhage and five became anxious after the procedure commenced). Sedation was rarely required and there were no adverse effects of the anaesthetic on surgical procedures or patients' vision. The authors conclude that peribulbar block provides satisfactory anaesthesia and that day ophthalmic surgery is safe and effective.
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PMID:Day ophthalmic surgery: aspects of perioperative care. 915 52

Sedation is often required to achieve immobilisation of small children during radiotherapy to avoid irradiation of normal tissues during the course of treatment. At the University College Hospital, Ibadan radiotherapists provide sedation for such patients with administration of parenteral and/or oral promethazine, diazepam, chlorpromazine and paraldehyde. This retrospective review of 84 children aged 1 month to 6 years who received sedation for radiotherapy over a period of twenty-one to twenty-eight days showed that 48% had complications. These included injection cellulitis (85.3%), injection abscess (4.87%), paresis of the lower limb (7.3%), aspiration pneumonia (2.4%). Anaesthetists in developing countries should be encouraged to extend their expertise in caring and resuscitation of sedated or unconscious patients to the radiotherapy unit. This will allow for the use of a wider variety of sedative agents and better monitoring as well as minimise or eradicate complications.
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PMID:Complications following sedation of paediatric oncology patients undergoing radiotherapy. 992 Oct 85

Sedation and analgesia will be required in the mechanically ventilated pediatric trauma patient. Adequate provision of both has a number of beneficial physiologic and psychologic effects. There are a number of categories of sedatives available for use. To provide optimal management and avoid adverse sequellae, an understanding of the pharmacology of these agents should guide their use in this group of patients, who are likely to have variable pharmacokinetic responses and therapeutic goals. Neuromuscular blockade is warranted in only a select population of mechanically ventilated ICU patients. Given newer ventilator technology and modes, it is certainly possible to achieve patient-ventilator synchrony with the use of sedation alone. Neuromuscular blockade is associated with a number of possible adverse effects, including prolonged weakness or paresis, and prohibits ongoing clinical assessment. When the use of this therapy is deemed necessary, it is again essential to understand the pharmacodynamics and pharmacokinetics of the available agents to avoid potential complications.
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PMID:Paralyzation and sedation of the ventilated trauma patient. 1158 7