Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Laryngeal complications in systemic lupus erythematosus (SLE) are rarely described. They range from hoarseness to life-threatening respiratory distress. To our knowledge, previous reports describe laryngeal involvement with SLE occurring only during periods of active disease. We saw a patient with inactive SLE in whom hoarseness and exertional dyspnea developed as a result of arytenoiditis and vocal cord paresis during steroid tapering. The condition responded dramatically to readjustment of her steroid dosage. Involvement of the larynx with SLE is a potentially life-threatening complication and may occur in patients with either active or inactive disease. It is an indication for close observation and steroid therapy in patients with SLE.
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PMID:Laryngeal complications in a patient with inactive systemic lupus erythematosus. 647 11

A 5-year-old caprine doe was examined for abdominal enlargement and inability to stand. Hydrops uteri was diagnosed via ultrasonography, and was determined to be the cause of hind limb paresis. The placentomes appeared to be abnormal in shape and number. Uterine fluid electrolyte concentrations were similar to fluid from cows and sheep with hydrops amnion. Two fetuses were dead at the time of induced parturition. Hydrops uteri is rare in goats and, in the goat of this report, was believed to be caused by pregnancy with an unusual goat-sheep hybrid. The placental abnormalities discovered by ultrasonography may have been responsible for the abnormal accumulation of fluid, but a fetal abnormality also was considered to be possible.
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PMID:Hydrops uteri in a caprine doe pregnant with goat-sheep hybrid fetuses. 779 Mar 9

An 18-month-old Cameroon dwarf goat doe had chronic, bilateral hindlimb paresis and difficulty in rising two months after the birth of a normal kid. The doe was weak, pyrexic and had a purulent vaginal discharge. A large, firm mass was palpated in the caudodorsal abdomen. Abdominal ultrasonography revealed an ill-defined impenetrable mass which cast acoustic shadows. Radiography identified the mass as a fetus. The doe had a low normal haematocrit and a marked leucocytosis. A caesarian section through the caudal left paralumbar fossa was attempted, but contraction of the uterus had trapped the fetus in the cranial entrance of the pelvic canal preventing the uterus from being exteriorised. Adhesions were found between the uterus and abdominal viscera. The doe's inability to rise was attributed to the chronic pressure exerted on the ischiadic nerve by the fetus. A diagnosis of fetal mummification secondary to obstructive dystocia and fetal death was made. Radiography was a better diagnostic tool than ultrasonography in this case.
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PMID:Postpartum mummification of a co-twin fetus in a Cameroon dwarf goat doe. 907 19

We report the case of a 72-year-old man who had contracted acute paralytic poliomyelitis in his childhood. Thereafter, he had suffered from paresis involving the left lower limb, with no relapse or progression of the disease. He began noticing slowly progressive muscle weakness and atrophy in the upper and lower extremities in his 60s. At the age of 72, muscle weakness developed rapidly, and he demonstrated dyspnea on exertion and dysphagia. He died after about 14 years from the onset of muscle weakness symptoms. Autopsy findings demonstrated motoneuron loss and glial scars not only in the plaque-like lesions in the anterior horns, which were sequelae of old poliomyelitis, but also throughout the spine. No Bunina bodies, TDP-43, and ubiquitin inclusions were found. Post-polio syndrome is rarely fatal due to rapid progressive dyspnea and dysphagia. Thus, the pathological findings in the patient are considered to be related to the development of muscle weakness.
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PMID:[An autopsy case of progressive generalized muscle atrophy over 14 years due to post-polio syndrome]. 2661 85

A six-year-old female goat was presented to the veterinary teaching hospital of the University of the West Indies with a history of progressive hind-limb paresis lasting two weeks. The doe developed a grade 6/6 holosystolic murmur during hospitalisation. Echocardiography revealed vegetative growths attached to cusps of the mitral and aortic valves. There was an accelerated aortic flow at 2.9 m/s and aortic insufficiency. The aortic vegetation was prolapsing into the left ventricle during diastole, causing it to contact the septal mitral valve leaflet. A diagnosis of mitral and aortic vegetative endocarditis, with a mitral kissing vegetation and mild aortic stenosis, was reached. The patient was placed on broad-spectrum antimicrobials. A short-term follow-up showed no resolution of clinical signs, and the animal eventually died. Post-mortem examination showed severe vegetative, fibrino-necrotic, aortic and mitral valve lesions. The goat also had a severe fibrino-suppurative mastitis. Histopathology confirmed the lesions to be vegetative endocarditis.
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PMID:Mitral Kissing Vegetation and Acquired Aortic Valve Stenosis Secondary to Infectious Endocarditis in a Goat with Suppurative Mastitis. 2999 9