Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 1986 in the CSR 978 cases of acute meningoencephalitis were notified, incl. 184 in the capital. In a group of 129 patients aged 1 to 63 years hospitalized at the First Clinic for Infectious Diseases in Prague-Bulovka (Paediatric Faculty Charles University) in 1986 the authors investigated the clinical course of acute meningoencephalitis in relation to the causal agent of the disease. The aetiological agent was assessed by isolation from cerebrospinal fluid or by isolation from faeces with the corresponding antibody response, or by serological examination only. In children under 15 years of age the etiological agent was assessed in 36%, in adults in 65%. In the investigated group, contrary to previous years (3), tick-borne encephalitis was involved which accounted for the majority of severe cases of the disease. The severe clinical course, manifested at first by symptoms of cerebral oedema with impaired consciousness, is more frequent with advancing age. In adults tick-borne encephalitis had a severe course in one third of the patients. In the other age groups the development was favourable, in particular in the group of children aged 4-10 years. As compared with previous years, there was no fatal case, no permanent paresis as a complication of the disease (2).
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PMID:[The clinical picture and etiology of meningoencephalitis in hospitalized patients in 1986]. 263 95

We report a 96-year-old Japanese man who developed a sudden onset of left hemiplegia and coma. He was found to have diabetes mellitus, hypertension, and atrial fibrillation since 1996 with occasional episodes of congestive heart failure. He was otherwise apparently well until July 5 of 1997 when he developed a sudden onset of unresponsiveness and convulsion involving his right hand and was admitted to our hospital. On admission, his BP was 210/120 mmHg, heart rate 76/min and irregular, BT 36.5 degrees C, and Cheyne-Stokes respiration. General medical examination was otherwise unremarkable. Neurologic examination revealed semicoma, conjugated deviation to the right, loss of oculocephalic response, left facial paresis of central type, flaccid left hemiplegia, and bilateral Babinski sign. Pertinent laboratory findings are as follows: BUN 47 mg/dl, creatinine 1.46 mg/dl, GPT 69 IU/l, LDH 1,142 IU/l, and CK 385 IU/l. A chest x-ray film revealed cardiac enlargement and EKG showed left ventricular hypertrophy and atrial fibrillation. Cranial CT scan revealed low density areas involving the right anterior cerebral and the right posterior cerebral artery territories. He was treated with an intravenous osmotic agent and short course of intramuscular steroid. He remained unconscious despite these treatment and developed sudden cardiopulmonary arrest three weeks after the admission. The patient was discussed in a neurological CPC and the chief discussant arrived at the conclusion that the patient had suffered from cerebral embolism of cardiac origin. The cause of the death was ascribed to acute subendocardial myocardial infarction. Most of the participants agreed with this conclusion. Postmortem examination revealed an old subendocardial myocardial infarction involving the posterior septal region and posterolateral wall of the left ventricle. Neuropathologic examination revealed hemorrhagic infarctions involving the territories of the right anterior cerebral, right middle cerebral, right posterior cerebral, and left anterior cerebral arteries. The left A1 portion of the anterior cerebral artery was hypoplastic, and the left pericallosal artery appeared to have been receiving blood supply from the right anterior cerebral artery through the anterior communicating artery. The large arteries in the base showed marked arteriosclerosis; particularly, the initial portion of the right posterior artery showed near complete arteriosclerotic occlusions. These characteristic arterial changes appeared to be the reason why this patient suffered from an extensive infarction from what appeared to have been a single episode of cerebral embolism probably initially involving the right internal carotid artery.
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PMID:[A 96-year-old man with consciousness disturbance, convulsion, and left hemiplegia of acute onset]. 1006 67