Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Transcranial magnetic stimulation was performed in 20 patients with pontine infarction who had initially some degree of hemiparesis. Only patients with a well defined lesion on magnetic resonance imaging that was appropriate for the neurological signs were included. Recordings were made from the abductor pollicis brevis muscle (APB) bilaterally. The degree of hand paresis was estimated clinically and related to the following parameters: central motor conduction time (CMCT), interside latency difference of total latency, and amplitude ratio of affected to unaffected side. Increasing degree of paresis was associated with increasing latency parameters and decreasing amplitude ratio. In the four patients with severe paresis a low amplitude response could be evoked and CMCT was delayed by up to 10 ms. When the paresis had resolved at the time of transcranial magnetic stimulation CMCT was normal. However, amplitude ratio was less than 100% in all but one patient, with most of the values ranging between 40% and 60%, which indicates a subclinical pyramidal tract lesion. Median nerve sensory evoked potentials (SEP) and related interside latency difference to amplitude ratio N20/P25 were also recorded. In contrast to TCMS, decreased amplitude ratio of SEP was not associated with delayed latency. Clinically, the mild degree of and good recovery from paresis in ventral pontine infarction was remarkable.
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PMID:Transcranial magnetic stimulation in pontine infarction: correlation to degree of paresis. 158 14

The study aimed at investigation of clinical and neurophysiological features of pyramidal syndrome in patients with vascular damage of right- and left hemisphere in stroke. Forty patients with consequences of acute brain circulation damage were studied: 21 of them with right hemi-paresis (RHP) and 19--with left hemi-paresis (LHP). Cliniconeurological analysis, transcranial magnetic stimulation (TMS), evoked abdominal reflexes, movement motor potential method and somatosensory evoked potentials were used for the examination. Pronounced paresis, tone disturbance, Babinsky symptom, other extensor pathological feet signs, Zhukovsky hand reflex, pseudobulbar syndrome, gait disorder were determined more frequently in patients with LHP. Patients with RHP were characterized by more expressed distal hand paresis and pathological bending feet signs. Compared to RHP patients, those with LHP displayed significantly longer central conduction in TMS, increase of latent periods of components N20, P25, N30 of somatosensory evoked potentials and motor potential area reduction. Functional features of brain hemispheres may to play a certain role in pyramid syndrome formation, right hemisphere damage being characterized by more expressed pyramid disturbances. The data obtained allow to differentiate a great brain hemispheres role in descending motor control as to inhibiting and activating pyramid influences and hemisphere interactions.
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PMID:[Clinical and neurophysiological analysis of pyramidal syndrome in right and left hemisphere stroke]. 1244 60