Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A little girl who was suffering from chronic mucocutaneous candidiasis also had a cellular immune deficiency and undetectable IgA levels. She was treated continuously for 6 years with ketoconazole at the same dosage of 200 mg/day. She was rapidly clear from infection and did not relapse although her immune abnormalities persisted. During this long-term therapy, voluminous fusiform intracranial aneurysm appeared, causing a paresis of the four limbs. Are they mycotic aneurysms?
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PMID:Aneurysm associated with chronic mucocutaneous candidiasis during long-term therapy with ketoconazole. 249 56

This report presents the case of a healed 5-month-old infant with necrotising (malignant) bilateral otitis externa from acute mastoiditis on the right side and sepsis caused by Pseudomonas aeruginosa infection. Despite of immediately performed mastoidectomy, targeted antibiotics and intensive local treatment, two third of both external auditory canal's epithelium had shown subcutaneous concentric necrosis and ejection which have been removed with repeated necretomies. After the remission of inflammatory symptoms, successful bilateral auditory canal reconstructions were performed. The observed right peripheral facial paresis at the beginning of disease remained stationary. The patient healed with residual symptoms after 2 months of treatment. Neither immune deficiency, nor diabetes could have been proven.
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PMID:[Necrotizing otitis externa in a 5-month-old infant]. 1798 26