Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The study was performed to evaluate neurological complication of 562 patients who had undergone primary total hip replacement. Lesions of sciatic, femoral and common peroneal nerve occurred in 18 patients (3.2%). Paresis of peroneal nerve was demonstrated in 15 patients. Within this group 7 patients had elongation of the extremity above 4 cm, and 8 patient had it in the range of 2-3 cm. Paresis of common peroneal nerve took place after direct compression of region of fibular head. Lesion of femoral nerve happened twice. In the group of 14 patients clinical symptoms of nerve paresis healed spontaneously in 6-12 month time. In the group of 4 patients (0.7%) constant lost of dorsal flexion of the foot was observed.
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PMID:[Neurological complication after total hip replacement]. 1552 3

Femoral nerve palsy, mostly of iatrogen cause, leads to paresis of quadriceps muscle with complete loss of knee extension. Therapeutical options include neurolysis, nerve reconstruction or functional muscle transplantations. Another concept is the transfer of hamstring muscles as described in post polio surgery. We describe our experience of biceps femoris and semitendinosus muscle transfer for reconstruction of knee extension. From 2003 to 2007 seven patients (mean age 43) with complete loss of knee extension after femoral nerve lesion were treated. Nerve palsy was caused by direct lesion, traction, hematoma after collapse, lesion of lumbosacral plexus and an unclear muscle dystrophy. Indication for muscle transfer was due to long standing muscle paresis. All patients received a transfer of biceps femoris and semitendinosus muscle/tendon into the quadriceps tendon. Patients were immobilised in a cast for 6 weeks in extended knee position. Weight bearing started after 8 weeks. Operations went uneventfully. All patients were able to extend the knee postoperatively against gravity and were able to climb stairs without help. 4 Patients had complete knee extension, 2 had a lack of 20 degrees , one of 30 degrees. Daily routine was possible in all cases. No instability of knee joints occurred postoperatively. In a nerve lesion close to the muscle a nerve reconstruction should be aimed. If not performed or with unsuccessful outcome, muscle transfer is a good option to restore function. All recent studies describe good to excellent results with stable knees, allowing the patient to manage daily routine without assistance and to climb stairs up and down. Long term complications such as dislocation of patella or genu recurvatum were not observed in our patients. The latter results as typical complication in polio from weakening knee flexion through biceps femoris transfer, if the gastrocnemius muscle is not forceful enough. However in an isolated femoral nerve lesion this will rarely occur.
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PMID:[Reconstruction of quadriceps femoris muscle function with muscle transfer]. 2023 8