Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The early diagnosis of the motor functional outcome of the upper and lower limbs in patient with cerebrovascular disease is important in establishing a treatment plan. The purpose of this study was to establish a method to evaluate the severity of low density areas on CT scans in patients with hemiparesis caused by cerebral infarction. The subjects were 186 patients who were admitted on the day of onset, showed a low density area on CT images within 5 days of onset. Of these patients, 111 had cerebral infarction, and the other 75 had reversible ischemic neurological deficit (RIND). On CT images, the low density area in the slice of corpus calosum splenium (S-1) and that of ventricular body (S-2) was measured, and its relationship with motor functional results at the time of discharge was evaluated. The motor functional level was evaluated using Brunnstrom's stage. The findings are as follows: 1) Discriminant analysis was performed using an explanatory variable of 1 and an error rates of 5% or less. The severity of the low density area could be classified into 4 major types in S-1: I-IV; and into 3 subtypes in S-2: a, b, c. The 186 patients were topographically classified using the major types and subtypes. 2) The 75 patients with type I a, b, c and II a motor function recovered within 3 weeks (RIND). Of 16 patients with type II b, 10 recovered after rehabilitation for 3 weeks or more, but the other 6 showed remaining of motor impairment in the upper limbs. Of 29 patients with type II c, 5 recovered, but the other 15 showed remaining of motor impairment in the upper limbs. 3) Of patients with type III, none recovered completely. All patients with III c had hemiparesis. 4) In 3 patients with type IV b, Stage 1.2 paresis remained in the upper limbs and Stage 4.3 in the lower limbs. Of 38 patients with type IV c, 23 showed remaining of Stage 1.2 paresis in both upper and lower limbs, and the other 10 showed Stage 1.2 paresis in the upper limbs. 5) The severity classification of the low density area on CT images was closely related to the motor functional outcome of the upper and lower limbs. Therefore, this classification is useful for determining the treatment method early after onset.
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PMID:[Location of lesion on CT and motor functional outcome of the upper and lower limbs in patients with cerebral infarction]. 888 32

A 27-year-old woman with headache and right peripheral facial nerve paresis persisting for over 25 days, and left hemiparesis for 2 days, which had all been gradually improving, was admitted to our hospital as she suddenly developed horizontal and vertical diplopia. She had right fourth and sixth cranial nerve pareses, papilledema, and right orbital venous congestion, and also experienced a seizure on the day of admission. Magnetic resonance (MR) imaging and MR venography revealed complete superior and inferior sagittal sinus thromboses and significant collateral venous channels, but no parenchymal lesion. Fourth and seventh cranial nerve pareses and the left hemiparesis resolved completely within 2 days, but she concurrently developed an episode of right hemiparesis, which lasted for 30 minutes. The patient recovered with medical therapy. MR venography showed recanalization of both sinuses. She was neurologically intact except for minimal right abducens nerve paresis at discharge, 40 days after admission. Multiple cranial nerve pareses with transient ischemic attack is an extremely rare manifestation of superior sagittal sinus thrombosis. Transient functional disturbance due to temporary reduction of tissue perfusion caused by overload of the collateral channels is more likely to be responsible for the transient ischemic attack and reversible ischemic neurological deficit.
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PMID:Complete superior and inferior sagittal sinus thromboses with multiple cranial nerve pareses and transient ischemic attack--case report. 1237 94