Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nutritional or secondary hyperparathyroidism in a litter of German shepherd dogs is reported. The bitch lost interest in the litter 2 weeks post partum, the owner proceeded to feed the pups on a mainly meat diet (low in calcium) together with whole wheat bread (high in phosphate) until they were presented at Onderstepoort at the age of 6 weeks. Clinically the pups showed poor growth, posterior paresis and pain on palpation of the long bones. Radiological examination revealed decreased bone density and thickness of bone cortices. A diagnosis of nutritional or secondary hyperparathyroidism was made. The diet was corrected and in addition the pups were treated with a balanced supplement of calcium and phosphate with very good clinical response. The pathophysiology of nutritional or secondary hyperparathyroidism as well as ricketts and hypertrophic osteodystrophy as differential diagnoses are discussed.
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PMID:[Nutritional or secondary hyperparathyroidism in a German shepherd litter]. 725 68

A nine-year-old female Black-footed African penguin ( Spheniscus demersus ) was presented for necropsy after a history of reproductive abnormalities, paresis of limbs, weakness and sudden death. Post-mortem examination revealed soft keel, collapsed rib cage with beading of the ribs and bilateral parathyroid enlargement. Classical histological lesions of fibrous osteodystrophy with osteomalacia were observed in the ribs, vertebrae and to a lesser extent femur and tibiotarsus associated with hyperplasia of parathyroid glands. This represents the first report of nutritional secondary hyperparathyroidism in birds of the order Spheniciformes , most likely caused by low level of calcium supplementation during egg laying. The reproductive abnormalities observed in this penguin and others from the same group (asynchronous egg laying cycles, abnormal breeding behavior) were most likely exacerbated by the lack of an adequate photoperiod mimicking the natural daylight pattern.
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PMID:Nutritional secondary hyperparathyroidism and fibrous osteodystrophy in a Captive African Penguin (Spheniscus demersus) similar to osteomalacia in poultry. 3306 6