Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Management of cystic hygroma in 25 children as practised in Lagos, Nigeria during 1980 through 1989 was studied. Thirteen (52%) were infants out of which 7 were newborns. Thirty-three operations were performed including those for recurrences. There were 29 excisions out of which 22 (76%) were one-stage complete excisions. Complications included 4 cases of facial paresis, 6 recurrences and respiratory obstruction which led to death in 5 newborns, the only deaths in the series, and an operative mortality of 20.8%. A striking feature of this study is the observation that some recurrences occurred at sites which were normal at the initial or previous excision. Such recurrences led to 4 surgical operations at different times in one child. The term 'Progressive Infilterating cystic Hygroma' (PICH) is being suggested to distinguish this type from the ordinary cystic hygroma.
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PMID:Management of cystic hygroma of the head and neck in Lagos, Nigeria; a 10-year experience. 159 61

Inflammatory reaction is very important for formation of the neomembrane of chronic subdural hematoma (CSDH). The present study evaluated medical treatment with the platelet-activating factor receptor antagonist, etizolam, for the resolution of CSDH, and the factors indicating surgery or conservative therapy. Alternate patients were assigned to the etizolam group or control group without medical treatment. Patients in the etizolam group received 3.0 mg etizolam per day for 14 days. A total of 53 patients were followed up for at least 6 months. Univariate analysis of differences in demographic characteristics, clinical findings, and initial computed tomography (CT) findings, and multiple logistic regression analysis of the relationship between etizolam treatment and requirement for surgery using age, sex, low density of hematoma on CT, and paresis as confounders were performed. Etizolam treatment (adjusted odds ratio [OR] 0.156, 95% confidence interval [CI] 0.024-0.999, p = 0.049) was negatively correlated with requirement for surgery. Low density of hematoma (adjusted OR 0.125, 95% CI 0.019-0.846, p = 0.033) was found to be an independent negative predictor, and paresis as an initial symptom (adjusted OR 6.35, 95% CI 1.04-38.7, p = 0.045) was an independent positive predictor of requirement for surgery. Etizolam administration can promote the resolution of CSDH, especially at the stage of hygroma appearing as low density on CT. Surgery is recommended if the patient presents with paresis.
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PMID:Effect of platelet-activating factor receptor antagonist, etizolam, on resolution of chronic subdural hematoma--a prospective study to investigate use as conservative therapy. 1637 49