Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We reported a 62-year-old male with cerebral thrombosis presenting global aphasia without hemiparesis. The patient had an episode of aphasia 15 years ago, but recovered within 6 months. This time he had transient right sided mild hemiparesis, then he became aphasia next morning. When we examined at day 10 and day 15, his consciousness was clear, nothing he could speech, he could not understand or repeat. We diagnosed him global aphasia, but he had no hemiparesis except for right facial mild paresis and was able to walk. CT scan showed low density area in left and right posterior, left anterior watershed and left terminal zone. Cerebral angiography disclosed thrombotic occlusion of main trunk of left middle cerebral artery, and ambient segment of right posterior cerebral artery. Global aphasia without hemiparesis has been said a sign of embolic encephalopathy. This case was considered a very rare case, because he revealed global aphasia without hemiparesis by thrombotic occlusion.
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PMID:[A case of cerebral thrombosis presenting global aphasia without hemiparesis]. 169 61

Calcification of ligamenta flava in the cervical spine is rarely seen. Only few cases in the literature have been available. Recently we have had experience with two cases on that lesion who had progressive radiculomyelopathy. The purpose of this report is not only case presentation but also an analysis of 11 cases from the literature in clinical, radiological and histological aspects. Case 1 was a 60-year-old woman who had numbness in both hands, mild weakness of the right foot on walking and clumsiness of the right hand. Ten years before she had suffered tbc. meningitis, but no history of neck injury. Neurological examination revealed spastic paresis in right extremities, muscle atrophy in both forearms, hypesthesia and hypalgesia in both hands and feet. Vibration sense was disturbed below the knee joint and both feet. Sphincter function was normal. Radiological examination of cervical spine revealed oval calcified nodules in the posterior spinal canal at the level of C34, C45, C56 and C67. These were all situated in the paramedian portion and symmetrically situated at C56. Air myelogram demonstrated that the spinal cord was displaced forward and choked by the posterior situated calcification. Cervical laminectomy was carried out from C2 through Th1 and calcified nodules in the hypertrophied ligamenta flava were successfully removed. Case 2 was also 66-year-old woman who had been suffering from cerebral thrombosis with left hemiparesis. In addition with left hemiparesis she started to complain with paresthesia in right hand, deteriorated numbness in left extremities and gait disturbance developed a year later.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Radiculomyelopathy due to calcification of the cervical ligamenta flava--report of 2 cases and a review of literature]. 665 77

It is well known that thromboembolism is 1 of the most serious side effects of oral contraceptives (OCs). In Japan, however, reports of thromboembolism following use of OCs are rare, since their clinical use in Japan is restricted to treatment of menstrual irregularities. We reported here on 2 patients affected with cerebrovascular occlusive diseases associated with the administration of OCs. The 1st case was that of a 32-year old woman who developed headaches, paresis, and dysesthesia of the right limbs following daily intake for 20 days of OCs (0.15 mg mestranol and 5 mg lynestrenol). Neurological symptoms as well as examinations led to the diagnosis of a kind of thalamic syndrome due to cerebral thrombosis. The 2nd case was that of a 37-year old woman who developed right hemiparesis following daily consumption over a 21 day period of OCs as administered above. Clinical symptoms and neurological examinations led to the diagnosis of right hemiparesis due to cerebral thrombosis. The pathogenesis of cerebral thrombosis caused by taking OCs was discussed mainly in connection with coagulation and fibrinolysis. Certain evidence suggesting that hypercoagulability may play a major role in the pathogenesis of thromboembolism during OC ingestion has been derived from the works of other investigators. It is true that estrogen in this compound may induce a state in which an increase in coagulation factors together with a decrease of antithrombin 3 combine to produce hypercoagulation; laboratory tests with our patients, however, produced nothing compatible with a state of hypercoagulability. (author's modified)
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PMID:[Cerebral thrombosis in woman receiving oral contraceptives: report of two cases (author's transl)]. 746 38