Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030552 (paresis)
5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Results of bithermal caloric testing in 83 patients with unilateral peripheral vestibular disease, cerebellopontine angle tumors and vertebrobasilar insufficiency were compared in order to find which response measurements identified the most abnormal responses in each disease category. A laboratory digital computer was used to quantitatively assess each caloric response and a large digital computer was used to statistically compare 110 measurements generated from each caloric test. Of the commonly used response parameters maximum slow component velocity (SVMx) and sum of slow amplitudes (SSA) were most sensitive in each category and duration of response (TDUR) was least sensitive. This order was maintained for the vestibular paresis (VP), directional preponderance (DP) and temperature effect (TE) formulas. The magnitude of DP was significantly correlated with the magnitude of spontaneous vestibular nystagmus and both occurred with approximately the same frequency in peripheral and central disorders. There was no reliable way of separating end-organ from VIII nerve or peripheral from central disorders on the basis of the caloric responses.
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PMID:Caloric testing. 3. Patients with peripheral and central vestibular lesions. 41 Mar 51

Balloon angioplasty has become a first-line therapy of symptomatic brachiocephalic occlusive disease. We review our own results of treatment of these lesions for the last two years. 16 patients (18 vessels--6 occlusions) with chronic limb ischaemia (9 cases), vertebrobasilar insufficiency (4 cases), ischemic stroke (2 cases); in one case angioplasty was performed as prevention before major abdominal surgery. Femoral approach was predominantly used; in 3 occlusions brachial approach was chosen. Stents were implanted in 4 cases of poor angioplasty result with severe limb ischaemia. Lesions were crossed in all stenoses and in 4 of 6 occlusions. Residual stenosis < 30% was attained in 10 pts. In 11 cases transstenotic gradient was relieved and a normal flow in vertebral artery was reestablished. There were two cases of acute upper limb ischaemia, one needed surgery. Reversible ulnar nerve paresis was noted in one patient, transient symptoms of postreperfusion syndrome in two. At follow up (mean 12 mo, range 1-30 mo) 1 restenosis was recorded. Balloon angioplasty is easy, safe and effective for treating brachio-cephalic stenoses. Recanalisation of occlusions is more difficult and risky. Treatment of stenoses should not be undully postponed; recanalisation should be reserved for patients with more advanced symptoms of the disease.
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PMID:[Balloon angioplasty of branches of the aortic arch]. 1094 85

The lateral (LF) and posterolateral (PLF) foramina are anatomical variants of the atlas. Both variants have been implicated in multiple neurological conditions including vertebrobasilar insufficiency, with symptoms such as dizziness, syncope, auditory and visual disturbances and paresis. The aim of this study was to conduct a systematic meta-analysis on the prevalence and anatomical characteristics of the LF and PLF. An extensive search of the major electronic databases was conducted to identify all studies that reported relevant data on the LF and PLF. No date or language restrictions were applied. Data on the prevalence, type (complete and incomplete), side, gender, and laterality of the LF and PLF, when available, were extracted and pooled into a meta-analysis. A total of 33 studies (n=10,190 subjects) were included in the quantitative analysis. The overall pooled prevalences of complete LF and PLF were 2.6% (95%CI: 2.1-3.1) and 1.2% (95%CI:0.6-2.0), respectively, while the overall pooled prevalence of the incomplete LF was 2.7% (95%CI:1.3-4.4) and the incomplete PLF was 0.7% (95%CI:0.0-1.8). When there was a complete PLF, a contralateral PLF (complete or incomplete) was found in 32.8% of cases. The geographical distribution of both variants was variable. The findings of this study provide an evidence-based foundation of anatomical knowledge of the two variants of the atlas. We recommend that physicians consider the possible role of the LF and PLF during the diagnosis of various neurological disturbances, especially in situations when all other possible explanations for the symptoms have been excluded.
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PMID:Lateral and posterolateral foraminal variations of the atlas: A meta-analysis. 2826 95