Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hemosorption and endolymphatic pharmacotherapy was included in the complex of treatment in 65 patients operated upon for spreaded forms of peritonitis and acute ileus. Hemosorption was performed within 12-24 h after operation, pharmacological agents (Aceclidine++, Cerucal, Obsidan) were introduced by antegrade endolymphatic infusions 4-6 h after hemosorption. The investigations have shown that in this case there rapidly appears intestinal peristalsis which is maintained not less than for 10-12 hours and in great part of patients it was completely recovered. Multiple stimulations by traditional methods were necessary in the control group to restore peristalsis. The combination of hemosorption and endolymphatic therapy may be recommended as an effective complex for the struggle against intestinal paresis in peritonitis and acute ileus in the postoperative period.
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PMID:[Hemosorption and endolymphatic therapy in the treatment of paralytic ileus in peritonitis and acute intestinal obstruction]. 197 63

Changes in the muscular layer and intermuscular nervous plexus are studied histologically, histochemically and electron microscopically using the model of faecal rat peritonitis. Alterations characteristic of water metabolism disturbances (edema) up to the coagulation or colliquative necrosis development of individual cells are revealed in the muscular layer. Damage to the cholinergic structures which can be interpreted as a reversible partial morpho-functional cholinergic denervation is found in the intermuscular nervous plexus. The above changes are the structural basis of the intestinal paresis in peritonitis. These changes are reversible if an early (up to one day) elimination of the inflammatory process occurs.
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PMID:[Changes in the muscular layer and the intermuscular nerve plexus of the intestines in experimental peritonitis in rats]. 227 Sep 82

Continuous hyperthermic peritoneal perfusion (CHPP) with a solution that contains mitomycin C (CHPP-M) has been clinically introduced as a prophylactic treatment for peritoneal recurrence of gastric cancer with serosal invasion. Two studies, each with a treated and a control group, were performed. In the historical control study the postoperative 3-year survival rate of patients (73.7%) in the treated group (n = 38) was significantly higher than the survival rate (52.7%) of those in the control group (n = 55) (P less than 0.04). In the random control study the survival rate (83%) of patients in the treated group (n = 26) was also higher than that (67.3%) of those in the control group (n = 21) in the 30 months that followed gastric surgery. However, there was no significant difference. In the historical control study with respect to the postoperative complications, anastomotic leak was observed in 8.5% of patients who were given CHPP-M and 12.8% patients who did not have CHPP-M. In the random control study anastomotic leak was observed in 3.1% of patients who had CHPP-M and 7.1% of patients who did not have CHPP-M. The incidence of adhesive ileus in patients having CHPP-M did not increase in historical or random control groups. Postoperative prolonged intestinal paresis or chemical peritonitis were not induced by CHPP-M. These results indicate that CHPP-M is a simple, safe, and readily available prophylactic therapy for peritoneal recurrence that may follow gastric cancer surgery.
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PMID:Prophylactic therapy for peritoneal recurrence of gastric cancer by continuous hyperthermic peritoneal perfusion with mitomycin C. 312 Nov 65

In rats with diffuse peritonitis obtained by intraabdominal administration of a 10% fecal suspension (0.8 ml X 100g) neurohistochemical methods were used to study the adrenergic and cholinergic innervation of muscular membrane of the small and large intestine. It is shown that the disturbance of cholinergic innervation comes along with the intestinal paresis. Adrenergic innervation, represented by separate bundles, is found to be slightly affected.
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PMID:[Neurohistochemical study of intestinal innervation in experimental diffuse peritonitis]. 334 60

Clinical findings for 5 new cases of colonic perforation in corticosteroid-treated dogs were presented and 8 other cases from the literature were reviewed. Colonic perforation was a fatal complication in all 13 dogs, 12 of which had had recent major surgery. Ten dogs were neurosurgical patients, 1 dog received medical therapy for head trauma and nonambulatory paresis, and 2 dogs were operated on for non-neurologic conditions. Dexamethasone was the most frequently used corticosteroid, and 12 dogs received a mean cumulative dose of 6.4 mg/kg over an average period of 5.1 days. Depression, anorexia, and emesis, the most frequent signs attending colonic perforation, became evident 3 to 8 days after surgery. Signs preceded death by an average of 22.3 hours. Correct antemortem diagnosis (5 dogs) and surgical intervention (3 dogs) had no effect on eventual outcome (mortality = 100%). Colonic perforation most frequently developed in the proximal descending portion and always involved the antimesenteric border. Gross fecal contamination of the peritoneal cavity and acute generalized peritonitis were evident in all but one dog. Adhesions were observed at the lesion site in 6 dogs, but prevented gross soilage in only one dog.
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PMID:Colonic perforation in corticosteroid-treated dogs. 370 Feb 9

The occurrence of relaparotomies is known to be 1,2% of operations on the abdomen organs. Pyo-inflammatory complications are responsible for more than half cases resulting in relaparotomies. Relaparotomies are divided into emergent and urgent, radical and palliative. A system for prognosis of complications and differential diagnosis of postoperative paresis of the gastro-intestinal tract and postoperative peritonitis is presented. Prophylactics of postoperative complications reduced lethality after relaparotomies from 79% to 56%.
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PMID:[Possibility of predicting and preventing postoperative complications leading to relaparotomy]. 399 6

In the last thirty years sterilisation was applied in 26(15.02%) women vaginally and in 147(84.97%) women by lower medial laparotomy. In 86(46.71%) cases the binding of the tubes was performed as an additional operation during caesarean section. The binding of the tubes was carried out by Madlener's method and in some cases by Pomeroy's method. In three cases there was repeated pregnancy. All early complications (fever, pneumonia, thrombophlebitis, paresis intestini, subileus, peritonitis, suppuration of a suture, dehiscence) were within percentage limits given by other authors. These complications are not meant to be connected with the binding of the tubes. All the patients declared that after operation they were feeling much better regarding their sexual life (there was no fear of possible pregnancy) and that they did not notice any reduction of the libido or any change in this field.
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PMID:[Complications in women after operative sterilization (author's transl)]. 733 82

The paper is based on clinical and experimental findings of one of the postoperative complications of purulent peritonitis, namely adhesion formation. The authors consider that impaired cytodynamic relationship in the focus of peritonitis concurrent with gastrointestinal paresis underlie the pathogenesis of the above-mentioned complication. In this connection, the authors propose a set of anti-adhesive measures, which involves prodigiosane cytomodulation and differential treatment of enteroparesis. Intestinal ultrasonic echocardiography was used for diagnostic purposes. Laparoscopy was employed in the surgical treatment of adhesive complications of peritonitis, which allowed relaparotomy to be eliminated or its traumaticity to be reduced to a great extent. There were no deaths and relapses of adhesive disease.
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PMID:[The current methods for the prevention, diagnosis and surgical treatment of the adhesive complications of peritonitis in children]. 768 87

The work is based on the analysis of treatment of 212 children with generalized purulent peritonitis of appendicular origin at 7 different pediatric surgical clinics of Russia. The total mortality rate was 1.9%. It is shown that the removal of pus from the abdominal cavity by aspiration has no advantages over its removal by means of moistened tampons. Irrigation of the abdominal cavity during the operation does not affect essentially the results of treatment of patients with generalized purulent peritonitis. Drainage of the abdominal cavity by means of an aspiration drain installed properly and methodically leads to a lesser number of postoperative abdominal abscesses and continuing peritonitis. Administration of antibiotics into the abdominal cavity at the end of the operation and in the postoperative period does not influence significantly a decrease in the incidence of postoperative purulent complications. Peridural anesthesia has no advantages over other methods in the control of intestinal paresis and prevention of adhesive intestinal obstruction.
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PMID:[Evaluation of methods for local treatment of generalized purulent peritonitis of appendicular origin in children]. 826 66

Protein malnutrition occurs in 41%-42% of peritoneal dialysis (PD) patients, indicating that the current intake of protein is inadequate in many patients. With an intake of protein > or = 1 g/kg/day, most continuous ambulatory peritoneal dialysis (CAPD) patients are in positive or neutral nitrogen balance, while with an intake below this there is considerable risk of negative nitrogen balance. Most CAPD patients are prescribed a diet containing 1.2 g/kg/ day protein or higher, yet the majority of patients have an intake lower than this. Several factors are associated with inadequate protein intake including older age, comorbidity, and loss of residual renal function when the dialysis regimen is inadequate. A minimum weekly Kt/V of 2.0 is needed to achieve a protein intake of 0.9-1.0 g/kg/day. Patients with peritonitis and a permeable membrane have increased losses of protein via the dialysate, and so are at risk for protein malnutrition. To prevent and treat protein malnutrition, routine assessment of both nutritional status and dialysis adequacy are needed. Patients with an adequate clearance (weekly Kt/V of 2.0 or higher, creatinine clearance of 60 L/week/1.73 m2), who are eating 1 g/kg/day and have no markers of malnutrition, including a normal serum albumin, require no intervention. Protein supplements can be prescribed to increase the protein ingestion to 1.2 g/kg/day or more, if the serum albumin is low, or if the patient is clinically malnourished with weight loss and decreased muscle mass. Gastro-paresis and esophagitis, common in PD patients, can be treated. If supplements, dietary counseling, and adequate dialysis regimen do not result in improvement of nutritional status, amino acid dialysate may be beneficial. One to two exchanges per day using amino acid dialysate converts the nitrogen balance from neutral to positive in malnourished CAPD patients. To use amino acid dialysate successfully, the physician must be sure that the clearance is adequate as the serum urea nitrogen rises; inadequate dialysis can result in uremia and decreased intake.
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PMID:Recommendations for dietary protein intake in CAPD patients. 886 18


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