Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of this work was an analysis of caloric directional preponderance prevalence in patients with vestibular neuronitis and coincidence of above mentioned symptoms with spontaneous and positional nystagmus. The examinations were carried out in 36 patients, aged 27-51, 19 women and 17 men. The vestibular reactions were recorded by electronystagmography and directional preponderance and mean angle velocity of the slow phase were calculated. It was pointed out that in vestibular neuronitis patients the directional preponderance may appear early and in great number of cases with canal paresis. However, in the late stages of vestibular neuronitis the directional preponderance may appear independently without the spontaneous and positional nystagmus.
 ...
PMID:[Directional preponderance of caloric nystagmus in vestibular neuronitis]. 260 84

The perverted nystagmus is a modification of the horizontal beating nystagmus (in classical caloric stimulation) by a vertical or rotatory mainly component. Experimentally, this disorder can be shown after an unilateral destroy of the superior or median vestibular nucleus. We show 32 cases of subjects with a perverted nystagmus. 75% of these subjects have a pure central disease and 20% a vestibular neuronitis. The perverted nystagmus had an upbeat component with the cold stimulation and downbeat component with the hot stimulation. It was accompanied by a spontaneous nystagmus in 66% (and 30% with vertical nystagmus). Some abnormal responses with the simultaneous bilateral vestibular caloric testing, were found in 95%. The analysis of the results of the unilateral caloric testing shown the frequent association: hyporeflectia (canal paresis) of one side and hyper-reflects of the other side. This fact would have evoked a mixed disease, peripheric and central (i.e. the vestibular neuronitis). Beside some pathogenic hypothesis, we prefer the fall of the inhibiting control of the superior semi-circular canal firing activity. Although, the perverted nystagmus is a simple and precious examination sign (it is directly shown with Frenzel glasses after caloric vestibular stimulation. It ought to do the brain stem topography diagnosis.
 ...
PMID:[The perverted nystagmus (author's transl)]. 734 Jun 71

Between 1972 and 1993 equilibrium and audiological examinations were made on 73 patients who had been diagnosed to suffer from vestibular neuronitis. In 23 of these patients, central nervous disorders (CND) were suspected from the result of tests of positional and positioning nystagmus, smooth pursuit, optokinetic nystagmus or auditory brainstem response. In this group of patients the frequency of associated disorders and vertiginous symptoms (dizziness) was statistically higher than in the remainder 50 patients who did not have CND. In the CND group the time interval between the onset and improvement or disappearance of all vertiginous symptoms, nystagmus and canal paresis was longer than in the non-CND group.
 ...
PMID:Central disorders in vestibular neuronitis. 761 Aug 68

We defined sudden vertigo as a sudden, unilateral peripheral vestibular dysfunction. The criterion for its diagnosis is a single episode of vertigo without cochlear and central symptoms. Among 20 patients with sudden vertigo there was no difference in clinical aspects between those with CP (canal paresis) (CP% > or = 25%) and those without CP (CP% < 25%). This suggests that sudden vertigo with CP is due to sudden vestibular dysfunction with predominant involvement of the lateral semicircular canal. Basically, vestibular neuronitis is considered to be due to acute unilateral neuropathy of the vestibular nerve. However, since we have no routine examination for evaluating vestibular nerve function, sudden vertigo with CP should be diagnosed as vestibular neuronitis. We then assessed the prognosis of sudden vertigo with CP (vestibular neuronitis). About two years after the onset of CP 4 of 10 patients had recovered. However, patients with persistent CP had a handicap in their everyday life because of the dizziness induced by head movements. The possibility of recovery of vestibular function in response to steroid therapy may improve the prognosis in vestibular neuronitis.
 ...
PMID:[Diagnostic and therapeutic problems in vestibular neuronitis: clinical implications for sudden vertigo]. 762 48

Clinical observations were made on 32 patients with vestibular neuronitis in the last 5 years: 14 male and 18 female, ranging from 15-76 years, the average being 46.3. Within the age distribution of the cases, two peaks were observed: a younger and an older group. Five patients (15%) had recently contracted infection of the upper respiratory tract before the onset of the disease, and two developed benign paroxysmal positional vertigo during the recovery period. Spontaneous nystagmus was observed in 19 cases (59%) in the first medical examination. There were several patients in whom there was the possibility of central lesions based upon the findings of equilibrium examinations. No relation was found between the degree of canal paresis and the time required for recuperation; however, the older patients took much longer to recover from the disease. Our results showed that there were considerable individual variations regarding the clinical findings, which may suggest that the pathological entity that creates this disease is not simple.
 ...
PMID:Clinical observation of 32 cases of vestibular neuronitis. 847 Apr 78

Progress of caloric response and subjective symptoms of 60 patients with vestibular neuronitis was evaluated by a long term follow-up study. Normalization of caloric responses was confirmed in 25 (41.7%) out of 60 patients, 20 of whom had recovered within 2 years of the onset of vertigo. The rate of the patients with canal paresis was about 90% after 1 month of the onset, and 80% after 6 months, while 50% of them still showed canal paresis after 5 or 10 years had passed. Complete relief from subjective symptoms was recognized in 34 (56.7%) cases during the follow-up period. We conclude that the prognosis of vestibular neuronitis is not always good, because vestibular function did not recover within normal levels in about half of the patients in spite of complete relief from subjective symptoms in many of them.
 ...
PMID:Progress of caloric response of vestibular neuronitis. 847 Apr 87

Eleven patients with vestibular neuronitis were followed up from 1988 to 1990. The relationship between the GBST and other vestibular examinations was investigated. Vertiginous symptoms showed relative improvement, but in the last medical examination 4 out of 11 cases (36.4%) complained of unsteadiness when their head was rotated and fatigued. Seven patients (63.6%) presented spontaneous and positional nystagmus at the first consultation, but only one patient (9.1%) at the last one. Seven patients (63.6%) showed canal paresis to caloric stimulation, while 3 (27.3%) showed normal responses. In the galvanic body sway test (GBST), 9 patients (81.8%) showed abnormal thresholds. There was no significant relationship between vertiginous symptoms in the last medical examination and prodromes, vertigo type, nystagmus, righting reflex, caloric stimulation or the results of the GBST.
 ...
PMID:Relationship between GBST and equilibrium examination in vestibular neuronitis. 847 Apr 91

In some previously reported cases, facial palsy, even in Bell's palsy, involved vestibular dysfunction. Vestibular dysfunction in facial palsy is considered to be due to a retro-labyrinthine disorder such as vestibular neuronitis or acoustic neuromas. For the past 9 years we have been using the galvanic body sway test (GBST) routinely for differential diagnosis of the vestibular system. This paper reports GBST detected, retro-labyrinthine disorders in facial palsy. From 1981 to 1989, equilibrium examinations were performed in 33 cases with Bell's palsy and in 12 cases with Hunt's syndrome within 2 weeks after the onset. GBST was tested in 10 out of the 17 cases showing canal paresis (CP) in the caloric test. Abnormal GBST responses were detected in 9 cases (90%), 4 (80%) with Bell's palsy and 5 (100%) with Hunt's syndrome. The incidence of abnormal GBST was very high not only in Hunt's syndrome but also in Bell's palsy. The results indicate that vestibular dysfunction combined with facial palsy is mainly due to a retro-labyrinthine disorder and suggest that what is called vestibular neuronitis might be caused by a pathogenesis similar to that of facial palsy.
 ...
PMID:Retro-labyrinthine disorder in cases with peripheral facial palsy. 847 Apr 92

Symptoms and incidence of neuroborreliosis (NB) were studied in ambulatory patients visiting the ENT clinic in Helsinki. Especially we tried to search for possible markers indicating the connection between vestibular neuronitis and NB. A total of 350 patients were screened with the enzyme-linked immunosorbent assay (ELISA) technique for possible antibodies against Borrelia burgdorferi (BB). Twelve patients had positive serological reactions for BB with sera titer levels ranging from 640-14700 (normal < 500). In 2 additional cases, NB was clinically confirmed. In 7 cases a history of tick bite and in 4 cases erythema chronicum migrans was confirmed. In 9 cases, vertigo was the predominant symptom, and in 3 cases the symptoms were linked to facial nerve paresis. Six patients suffered from hearing loss. In 7 cases, the diagnosis was initially settled as vestibular neuronitis. NB seems to be present in about 4% of cases with apparent otologic diseases in Finland. In the majority of the cases, the disease resembles vestibular neuronitis in the acute stage. Since NB is tractable, all patients visiting the ENT clinic, especially those with vertigo, should be screened.
 ...
PMID:Neuroborreliosis in the etiology of vestibular neuronitis. 847 May 5

We studied 28 patients with vestibular neuronitis treated at our hospital between 1997 and 1999. To determine the effects of steroid therapy on long-term canal prognosis and daily activity, we examined caloric tests and gave questionnaires to 12 steroid-treated and 16 nonsteroid-treated patients 2 years after onset. We found that canal improvement was 50% in the nonsteroid-treated group and 75% in the steroid-treated one. In cases with severe canal paresis (CP > or = 60%), canal improvement was 33% in the nonsteroid-treated group and 67% in the steroid-treated one. Steroid therapy at the acute stage of this disease significantly reduced the duration of spontaneous nystagmus and handicap in daily life due to dizziness induced by head and body movement, decreasing mood disturbance.
 ...
PMID:[Effects of steroid therapy on long-term canal prognosis and activity in the daily life of vestibular neuronitis patients]. 1176 90


1 2 Next >>