Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In hearing preservation surgery for the treatment of vestibular schwannoma (VS), one of the important factors is the determination of the origin of VS. In this study, we investigated the diagnostic significance of using an MRI obtained by the three-dimensional Fourier transform fast spin-echo technique (3D-reconstructed MRI) in order to determine the origin of VS. The subjects consisted of 20 patients with mainly intra-canalicular sized VS who underwent tumor removal at our hospital. The origin of VS was determined from the 3D-reconstructed MRI findings and the results of the caloric test. These findings were then compared with the surgical findings. In 15 out of 20 patients, the MRI findings closely corresponded to the surgical ones, while the origin of VS hardly could be detected when a tumor filled up to the fundus acoustics on the MRI findings of the axial sections. On the other hand, 6 out of 15 patients (40%) whose tumor originated from the inferior vestibular nerve showed canal paresis. In conclusion, 3D-reconstructed MRI is considered to be helpful in obtaining more precise information regarding the origin of VS compared to the caloric test.
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PMID:The diagnostic significance of the 3D-reconstructed MRI in vestibular schwannoma surgery: prediction of tumor origin. 1195 36

The article presents the group of five patients with clinical and radiological symptoms of trigeminal neurinoma that were operated on in the Neurosurgical Clinic of Central Clinical Hospital of Military Medical Academy in the five-years period (1995-2000). Three of them were operated in a single step procedure from subtemporal and suboccipital approach. Two other were operated in two steps, also from subtemporal and suboccipital approaches. Four neurinomas were removed radically, as confirmed by CT, and MRI scans. All the patients are independent and professionally active. Complications observed after the operation were: persistent anaesthesia in the trigeminal area, atrophy of the masseter muscle, transient paresis of the facial nerve with ulceration and opacification of the cornea, and transient paresis of the abducens nerve.
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PMID:[Surgical treatment of trigeminal neurinoma]. 1218 14

We present an unusual case of diffuse large B-cell lymphoma within pontocerebellar angle schwannoma in 62-year-old woman. The patient suffered for 5 months with V, VII and VIII nerves paresis and with cerebellar ataxia. CT scan demonstrated large hyperdensive mass in cerebellopontine angle translocating cerebellar hemisphere and cerebral trunk. The patient was subjected to surgery and the tumour was removed totally by suboccipital retromastoidal right craniectomy approach. Histopathological examination revealed schwannoma infiltrated with high grade B-cell lymphoma. The patient did well following surgery without any other lymphoma manifestations, and she died from a heart attack 20 months later. Solitary lymphoma of pontocerebellar angle coexisting with schwannoma is an unusual finding, thus our case is the first report.
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PMID:Coexistence of diffuse large B-cell lymphoma within pontocerebellar angle schwannoma. 1223 Feb 55

Two patients with vagal schwannoma manifesting as deafness with no lower cranial nerve paresis were treated surgically. A 42-year-old male underwent partial resection of the tumor, which was tightly adhered to the cranial nerves, to prevent lower cranial nerve paresis. A 29-year-old female underwent total removal of the tumor without complications. The patients recovered useful audition with no postoperative deficit.
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PMID:Recovery of audition after favorable resection of vagal schwannoma. 1247 19

Tumours of the brachial plexus according to present classification are included to soft tissue tumours. Because of rare occurrence of these tumours diagnostic and operative experience is relatively small. There is also a few number of publications regarding tumours of the brachial plexus. Therefore the aim of the study was to present our experience in the surgical treatment of tumours of the brachial plexus basing on the material of 5 cases treated in the years 1997-2001. There were 4 males and 1 female, age from 17 to 58 years old. Four patients were under 27 years old. In 3 cases tumours of the brachial plexus invaded the spinal canal through the intervertebral foramen and caused spinal cord compression (type A). In 2 cases tumours involved only plexus elements (type B). In 2 cases tumours were associated with neurofibromatosis type II. Five cases of neural sheath tumours included 2 schwannomas, 2 neurofibromas and 1 schwannoma malignum. All patients underwent surgery. In case of schwannomas and neurofibromas the surgical removal was radical without impairment of brachial plexus function. In case of a giant schwannoma malignum tumor, which caused flaccid paresis and symptoms of insufficient blood, supply with severe pain in the upper limb radical extirpation was also possible. In type A tumours in the first stage intraspinal part of the tumor was removed. Follow up observation lasted from 3 months to 4 years. The result of treatment of benign tumours was very good with complete function recovery of the upper limb, pain disappearance and no symptoms of recurrence in the long postoperative period. In case of malignant schwannoma in the early postoperative period both pain and symptoms of blood supply disturbances completely disappeared. The patient died 12 months after the operation because of tumor dissemination. Benign tumours of the brachial plexus can be effectively surgically treated using microsurgical techniques and, if necessary, nerve grafting. In case of malignant tumours many authors also recommend surgery with optimal sparing of the brachial plexus function and subsequent radio and chemotherapy. Low number A few cases in our series makes impossible to draw any epidemiological conclusions.
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PMID:[Brachial plexus tumors--neurosurgical treatment]. 1252 17

The aim of this study was to present our experience in MRI diagnosis of 23 patients with the clinical findings suggesting Tolosa-Hunt syndrome (THS). Cranial MRI studies of the patients with a clinical history of at least one episode of unilateral or bilateral orbital and periorbital pain, and associated paresis of one or more of third to sixth cranial nerves, were performed on a 1.5-T MRI scanner. Whereas 5 patients had the diagnosis of THS, paracavernous meningiomas in 4 patients, pituitary macroadenomas with cavernous sinus infiltration in 3 patients, Meckel's cave neurinoma in 1 patient, and suprasellar epidermoid in 1 patient were surgically proven MRI findings. Other pathological MRI findings were leptomeningeal metastases in 3 patients, granulomatous pachymeningitis sequelae in 2 patients, and aneurysm with compression on cavernous sinus in 1 patient. Three patients had normal MRI findings. The incidence of radiologically proven diagnosis of THS among the patients with the clinical findings suggesting THS seemed to be low in our study. In conclusion, MRI is the most valuable imaging technique to distinguish THS from other THS-like entities, and permits a precise assessment, management, and therapeutic planning of the underlying pathological conditions.
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PMID:MRI findings in the patients with the presumptive clinical diagnosis of Tolosa-Hunt syndrome. 1254 Nov 6

The incidence of solitary neurofibroma of the facial nerve originating in the parotid region is extremely low. We report a case of a solitary neurofibroma in a 30-year-old male, who initially presented with a parotid mass without facial paresis or paralysis. A chain of small nodules had been palpable in the right parotid region for the previous 2-3 years. MRI and CT scans revealed several small ovoid lesions extending from the frontal margin of the parotid gland to the retromandibular region. The lesions were surgically removed. The main trunk of the facial nerve was adherent to the dorsal side of the largest nodule; however, this mass was resected atraumatically. Histopathological examination indicated neurofibroma. The incidence, presentation, diagnosis and surgical treatment of intraparotid neurofibroma are discussed and compared with those of Schwannoma.
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PMID:A rare case of a facial-nerve neurofibroma in the parotid gland. 1255 Jan 28

A 33-year-old male presented with a rare intracranial oculomotor schwannoma not associated with neurofibromatosis manifesting as an 8-month history of right oculomotor nerve paresis. Neuroimaging examinations revealed a 4-cm mass in the right crural cistern. The tumor was totally removed. The right oculomotor nerve paresis resolved 7 months after surgery. Removal of the oculomotor or trochlear schwannoma usually results in parent nerve paresis, but subcapsular tumor resection in our case probably allowed complete recovery of the nerve function.
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PMID:Schwannoma in the crural cistern removed without permanent functional deficits--case report. 1262 89

Computed tomography (CT) has examined 200 patients (400 temporal bones) at the age of 0-74 with unaffected facial nerve and 28 patients with symptoms of peripheral paresis or paralysis of the facial nerve of different genesis. Polyposition CT of the temporal bone is an intravital noninvasive method of the Fallopius' canal visualization. The canal is visualized on the tomograms in 100% cases irrespective of the patients' age. The following causes of n. facialis paresis were revealed: neurinoma of the facial nerve, sarcoma of the temporal bone, destruction of the tympanic canal wall in chronic otitis media, fractures of the temporal bone, malformations of the Fallopius' canal in malformations of the temporal bone, stenosis of the canal in fibrous dysplasia. The above alterations of n. facialis canal determine further therapeutic policy.
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PMID:[Oval window canal and CT-diagnosis of peripheral pareses of the facial nerve]. 1460 62

The aim of this study was to calculate the sensitivity of the head-shake test for peripheral and central vestibular dysfunction associated with unilateral sporadic vestibular schwannoma and to discuss the feasibility of using the head-shake test as a screening test. The study group consisted of 102 patients with unilateral sporadic vestibular schwannomas, who were seen consecutively for preoperative vestibular assessment, including the head-shake test. The sensitivity of the head-shake test for vestibular schwannoma was found to be 22%, and the sensitivity and specificity of the head-shake test for canal paresis (>/=25%) were found to be 27% and 88%, respectively. Patients with abnormalities in the central vestibular system and with a greater canal paresis were more likely to have head-shake nystagmus, although, even for severe canal paresis, the sensitivity of the test remained low at 36%. The direction of nystagmus was found to be contra-lateral to the side of the tumour in 86% of patients. It was concluded that the head-shake test is of insufficient sensitivity to be used as a screening test either for vestibular schwannoma or for vestibular-system abnormalities associated with vestibular schwannoma. The deduction is made that the head-shake test is of insufficient sensitivity or specificity to be of clinical value as a screening test for vestibular dysfunction in a general population with symptoms of imbalance.
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PMID:Head-shaking nystagmus in patients with a vestibular schwannoma. 1461 68


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