Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A disease characterized by paresis and paralysis was seen in 7-9-day-old broiler chicks after vaccination in the neck area at day-of-age with a live virus vaccine containing viruses of Marek's disease, fowl pox, and infectious bursal disease. Affected birds presented with variable signs of ataxia, lateral recumbency, leg paralysis, and twisting or S-shaped flexure of the neck. Gross lesions noted at necropsy included swelling and edema of the subcutaneous tissues and muscles of the neck at the injection site area. A heavy mononuclear inflammatory cell infiltration was seen in the subcutaneous tissues, connective tissues, and muscles of the neck at the injection site. In some cases, the inflammatory process extended along fascial planes to involve the epidural spaces surrounding the spinal cord. Fatty changes with possible demyelination of nerve fibers were noted in some sections of the spinal cord adjacent to the inflammatory lesions. Clusters of poxviruses were found within some inflammatory lesions on transmission electron photomicrographs.
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PMID:Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine. 1291 18

Neurolymphomatosis is a rare condition and may be the first and only manifestation of a non-Hodgkin lymphoma. We present the case of a 59-year-old patient with fluctuating gluteal pain for 5 years and progressive palsy of the left lower extremity, leading to severe walking difficulties. The neurologic examination revealed pronounced atrophy, flaccid paresis, and sensory loss in the area of innervation of the left sciatic nerve. Electroneuromyography showed a severe sensomotoric axonal lesion of the left sciatic nerve. Biopsy of the lesion revealed diffuse large B-cell lymphoma. Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography was performed for staging, showing a high FDG uptake of the left sciatic nerve. FDG-positron emission tomography/computed tomography after six cycles of chemotherapy showed complete metabolic response.
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PMID:Sciatic nerve neurolymphomatosis - extent and therapy response assessment with PET/CT. 1766 43

An 8-year-old girl presented with back and leg pain and left arm and leg paresis. Lumbar puncture was suggestive of lymphocytic meningitis without identified organism. A second lumbar puncture demonstrated a large number of lymphoid B cells, with positive immunohistochemical staining for CD20 and CD25, proving the diagnosis of neurolymphomatosis. Brain and spine MRI demonstrated involvement of cervical and lumbosacral nerve roots. FDG PET/CT showed multiple bone metastases in addition to nerve involvement. Postchemotherapy FDG PET/CT demonstrated complete metabolic response.
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PMID:FDG PET/CT in Pediatric Neurolymphomatosis. 2828 46