Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Forty-eight patients were given serial injections of botulinum toxin in their eyelids for treatment of eyelid spasm during a two-year interval. Ninety-four percent obtained relief of spasm from botulinum toxin injection. The duration of the spasm-free interval as well as the incidence of ptosis and of diplopia was dose dependent. The marked increase in the incidence of these side effects with only a small increase in the duration of the spasm-free interval, when a dose of 25 units per lid was used, leads the authors to conclude that this dose is too high and should not be used. Since diplopia was most commonly caused by paresis of the inferior oblique muscle, and since blepharospasm usually can be controlled by excising the upper lid protractors, further studies are required to determine whether lower lid injection is necessary and, if it is found to be so, whether injecting only the lateral portion of the lid would be adequate.
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PMID:Treatment of facial spasm with botulinum toxin. An interim report. 376 37

Chronic inflammatory sinus disease is a common process, sometimes requiring nasal and paranasal sinus surgery. Extraocular muscle dysfunction is a rare surgical complication of sinus surgery, but has been reported. Previous studies have been concerned with trauma to the medial rectus muscle resulting in severe paralysis or restriction. This study reports five patients with acquired strabismus and symptomatic vertical diplopia secondary to sinus surgery. In all patients, the resultant diplopia was disabling. Four patients had frontal sinus window surgery performed, with incisions placed in the supero-nasal quadrant of the orbit, below the eyebrow (a modified Lynch incision). Three patients acquired a superior oblique paresis and the fourth developed a Brown's syndrome. The location of the skin incision was critical to injury in the trochlear area. The fifth patient underwent a nasal polypectomy and antrostomy with secondary orbital hemorrhage and proptosis. A mild inferior rectus paresis was the result.
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PMID:Superior oblique and inferior rectus muscle injury following frontal and intranasal sinus surgery. 404 49

A 72-year-old woman had biopsy-proven cranial arteritis together with previously unreported findings of fluctuating mild ocular muscle paresis which had continued over the course of 4 1/3 years despite treatment with systemic corticosteroids. There was no optic nerve or central retinal artery involvement. This patient is unique in that muscle paresis is usually transient, lasting several days to a few weeks rather than 4 1/3 years. Response to steroids is usually prompt, and optic nerve or central retinal artery involvement is often associated. Therefore, we stress the importance of considering cranial arteritis in all patients over 55 years old who have transient or persistent diplopia, since immediate treatment may prevent optic nerve or central retinal artery involvement, which often follows within a few days.
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PMID:Ocular muscle paresis and cranial arteritis--an unusual case. 634 1

Three patients with evidence of inferior rectus muscle paresis were surgically treated for diplopia in downgaze following blowout fracture of the orbit or operative trauma. In each case, surgery involved the placement of two posterior fixation sutures 13 or 14 mm behind the physiologic insertion of the inferior rectus muscle in the contralateral eye. In one case, posterior fixation was combined with a small inferior rectus muscle recession. All three patients experienced relief of their diplopia and improvement in their binocular field of vision. There were no untoward sequelae and no surgically induced changes in primary position alignment.
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PMID:Incomitant vertical strabismus. Treatment with posterior fixation of the inferior rectus muscle. 638 Apr 65

Pontine gliomas have been considered to be out of indication for operative treatment. However, in case of a cystic type, evacuation of the cyst alone can possibly extend the survival time of the patient. Since the advent of high resolution CT the nature of the pontine tumor, whether cystic or solid, can be easily differentiated, and cystic ones subjected to operation will be increasing in number. We report a case of cystic pontine glioma associated with von Recklinghausen's disease. The patient showed a remarkable improvement in her neurological status after evacuation of the cyst. A 16-year-old girl was admitted to our clinic with complaints of tinnitus and hearing difficulty of the left ear, progressive gait disturbance and double vision. Neurological examination revealed a sensory disturbance on the left side of the face, left abducens palsy, left facial paresis, left deafness, left cerebellar ataxia, right hemiparesis and right hemisensory disturbance excluding the face. Signs and symptoms of increased intracranial pressure were absent. There were many cafe-au-lait spots and several subcutaneous nodules. CT scan demonstrated a cystic lesion with a mural nodule in the left cerebello-pontine angle. The patient underwent left suboccipital craniectomy, and a puncture of the cyst between the trigeminal and facial-acoustic nerves which were displaced dorsally yielded yellowish fluid. The content of the cyst was evacuated and its wall was widely opened. After the operation the patient showed a remarkable improvement in her neurological deficits only with left deafness remained unchanged. Histological examination showed anaplastic astrocytoma. She was discharged after irradiation of 5000 rads.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Cystic pontine glioma associated with von Recklinghausen's disease--report of a case]. 643 42

A 24-year-old man suffered an orbital impalement injury from a car aerial antenna that penetrated the medial third of the right lower lid. Immediately after the accident a convergent eye position, diplopia, and complete paresis of the upper lid as well as reduced abduction could be observed; the uninjured globe could not be moved beyond the midline. According to orbital tomograms and a traction test an incarceration of the medial rectus muscle was suspected. Electromyography 24 days after the accident revealed a peripheral paresis of the abducens nerve but an intact medial rectus muscle. Surgical exploration of the muscle was postponed, and the condition of the eye gradually improved; 8 days after the electromyography the clinical examination as well as the electromyogram showed near to normal results.
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PMID:Orbital impalement injury. An unusual case. 694 93

In 21 patients with traumatic diplopia, oculomyodynamometry (OMD) was used to examine the force of the extrinsic ocular muscles. In nine patients with blow-out fracture of the orbit, the greatest impairment in the active force and function of the incarcerated muscle was found in linear fractures. In 12 cases of traumatic paresis of the cranial nerves, OMD enabled the degree of paresis of particular extraocular muscles to be assessed, was helpful in establishing a correct diagnosis as well as prognosis for the restoration of function of the affected muscles, and provided data useful in planning the operative procedure.
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PMID:Value of oculomyodynamometry in traumatic diplopia. Direct ocular muscle force measurements. 706 64

Six patients had both restriction and paresis of the inferior rectus muscle after blowout fracture of the inferior orbital floor. All six were orthophoric in the primary position but had a severely constricted field of single binocular vision with troublesome diplopia on upgaze and downgaze. Recessing both the inferior rectus muscle and the superior rectus muscle in the injured eye greatly increased the field of single binocular vision. The symptoms improved in all six cases.
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PMID:Paresis and restriction of the inferior rectus muscle after orbital floor fracture. 709 Dec 87

Four cases of isolated superior oblique paresis are presented. The usual course of events was that of a gradually increasing diplopia and head tilt. All patients fulfilled the three-step test criteria, with a hypertropia that increased on side gaze to the ipsilateral side and on head tilt to the side opposite that of the paretic muscle. All patients were treated with a superior rectus recession. Three patients had their hypertropia reduced to between zero and 2 diopters. One patient needed, in addition to his superior rectus recession, an inferior rectus resection to eliminate the hypertropia. Vertical rectus surgery presents an alternative to superior oblique muscle tenotomy in treating inferior oblique paresis.
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PMID:Isolated paresis of the inferior oblique. 715 17

Complaining only of vertical diplopia, a 34-year-old woman had pupillary light-near dissociation, upward gaze paresis, convergence-retraction nystagmus, and skew deviation. Cranial computerized tomography excluded a space-occupying lesion. Additional history and examination established the diagnosis of clinically definite multiple sclerosis. Dorsal midbrain syndrome due to multiple sclerosis rare.
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PMID:Dorsal midbrain syndrome in multiple sclerosis. 719 4


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