Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Outcomes in self-care following rehabilitation in 226 patients were correlated with 11 stroke syndromes, reflecting several pathophysiologic disturbances subsequent to either infarction or hemorrhage in cerebral or vertebro-basilar vessels. Self-care was scored on a 20-point scale for bed movements, transfers, feeding, dressing, personal hygiene, and bathing. Interjudge error among therapists did not exceed 2.5%. Mean score in left cerebral infarction without aphasia was used as a referent value. Scores in left cerebral infarction with aphasia and right parietal lobe syndrome with and without spatial agnosia were similar to the referent. Brain stem dysfunction with spasticity and right cerebral infarction with paresis and spatial agnosia fell below the referent value (Pless than 0.05). Higher levels were achieved in the syndromes of left and right anterior cerebral artery territories, brain stem dysfunction with ataxia, and left parietal lobe syndrome with comprehension aphasia, although t-values were not significant. Length of stay among the 11 groups was fairly uniform except for the group with brain stem dysfunction with spasticity and the group with left hemiplegia with spatial agnosia. These groups indicated rather severe disabilities. Aside from neurologic dysfunction the range of scores was influenced by associated cardiopulmonary involvement.
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PMID:Neurophysiologic syndromes in stroke as predictors of outcome. 68 54

A procedure is presented which enables the physician to forecast the course a disease will take by looking through a list of items with attached numbers, i.e. weights, and simply adding the weights of those items which hold true for a specific patient. The application of this procedure to three different diseases, namely schizophrenia, facial paresis, and aphasia is presented and proves its accuracy. Furthermore, a Monte Carlo Analysis of the procedure underlying this method--multiple linear regression of dichotomous items--leads to recommendations concerning the optimum definitions of items and the structuring of data. The procedure is compared with other methods used in computer diagnosis and its main advantage, apart from its high reliability, i.e. independence of computers in its application, is stressed. Its application to other diseases is encouraged and the presentation of data for processing by this Department is invited.
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PMID:[A simple procedure to forecast the course of diseases (author's transl)]. 87 77

The authors report a case of epidermoid tumor of the lateral ventricle. Epidermoid tumors are relatively uncommon intracranial lesions and the one situated in the lateral ventricle has not been reported in this country. A 42 year old house wife was admitted to Asahi Central Hospital on February 14, 1973, complaining of progressive right hemiparesis for 2 years. The patient had no headache and no other symptoms of increased intracranial pressure. Neurological examination revealed disorientation, dyscalculia, amnestic aphasia, morter dysphasia, right facial paresis (central type) and right hemiparesis. The laboratory findings, which included complete blood count, serum electrolytes, urinalysis, electrocardiogram and blood Wassermann, were normal. Initial pressure of the spinal tap was 410 mmH2O and crystal clear CSF was obtained. tplain craniogram showed no calcification and was normal. The left CAG showed clearly the signs of the temporal lobe tumor (Fig. 1, 2, 3, 4.), but showed no early veins and no tumor stains. The brain scintigram was normal. A left temporo-parietooccipital craniotomy was performed. The epidural Echogram (horizontal section-Fig. 5, coronall section-Fig. 6) revealed the clear demarcated, multicystic round tumor in the inferior horn of the left lateral ventricle. After the whitesoap like tumor was totaly removed, the all interior surface of the left inferior horn of the lateral ventricle was seen (Fig. 8). Tumor was 5.5 cm in diameter and 50 g in weight. Histological findings of the tumor showed typical epidermoid (Fig. 9, 10). The origin of the intravetricular epidermoids and the usefulness of echo-encephalorgaphy were briefly discussed.
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PMID:[The epidermoid tumor of the lateral cerebral ventricle; report of a case (author's transl)]. 94 14

A systematic study of the emotional behavior of right and left brain-damage patients was conducted on large groups of patients with unilateral cerebral lesions. The incidence of "catastrophic reactions" was found to be significantly higher among the left brain-damaged patients, whereas "indifference reactions" were significantly more frequent in the group with right-sided lesions. The depressive-catastrophic reactions of left brain-damaged patients seemed due chiefly to marked difficulties in verbal expression, while the indifference reactions of the right brain-damaged patients were highly correlated with neglect phenomena for the opposite half of the body and of space. The meaning of the emotional reaction shown by left brain-damaged patients seems easy to understand, if we consider that these subjects are affected by aphasia and by a paresis of the right hand. More surprising and paradoxical is, on the contrary, the emotional behavior of the right brain-damaged patients. The hypothesis is advanced that the indifference of these subjects may be only apparent, and due to a strong need of denying illness. The prevalence of denial of illness among the right brain-damaged patients could be due to the "non verbal" functional organization which is supposed to be characteristic of this half of the brain.
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PMID:[Disorders of the emotional behavior during cerebral lesions]. 98 85

We have studied the intracranial cerebral circulation in 6 patients with bilateral ischaemic lesions of the internal carotid artery in the extracranial segment (2 significant bilateral stenosis cases; 1 case with bilateral thrombosis and 3 cases of unilateral thrombosis and significant contralateral stenosis). All the patients were males, their age being between the 5th and 8th decade. In a single case the neurological examination showed secondary left hemiplegia and recent right paresis of remittent type, while the other 5 patients had only transitory ischaemic attacks with hemiparesis or transitory aphasia. The lesions were revealed by means of duplex system echotomography (Aloka-Hellige Model SSD 630) and spectral analysis of Doppler signal (Vasoscan-Sonicaid) and they were confirmed later by bilateral carotid arteriography in all patients. The intracranial circulation was also followed up by non-invasive methods, making use of spectral-analysis of the Doppler signal with pulsed wave on TC-2 64-B apparatus. The cases studied by us, which present pathogenic situations more rarely encountered, have shown that none of them observed a 'mathematical model' of compensation of blood flow (BF). More exactly, 2 patients with the same type of lesions and topography did not have a unique model of compensation of BF. It seems that both the possibilities of individual self-regulation of cerebral BF and the extracerebral factors, especially those belonging to cardiac activity, are decisive in the compensatory activity of cerebral circulation, while the modalities in which this is accomplished depend chiefly upon the functional condition of the collateral arteries as a whole.
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PMID:Modalities of compensation of cerebral circulation through the circle of Willis in stenoses and occlusions of extracranial arteries. 135 74

We prospectively examined 11 patients with magnetic resonance imaging-documented infarction in the paramedian thalamopeduncular region, which is supplied by the superior mesencephalic and posterior thalamosubthalamic arteries. Variations in the size and rostral-caudal extent of infarction correlated with the following three clinical patterns: (1) With unilateral paramedian mesencephalic infarction, an ipsilateral third nerve paresis was accompanied by mild contralateral hemiparesis or hemiataxia. Contralateral ptosis and impaired upgaze were observed in two patients; one of them showed additional damage to the posterior commissure. (2) With bilateral infarction in the thalamopeduncular junction, involving the mesencephalic reticular formation, supranuclear vertical gaze defects were accompanied by impaired consciousness or memory, and mild aphasia in some patients. Persistent amnesia was observed only when the dominant anterior nucleus or mamillothalamic tract was damaged. (3) With larger thalamopeduncular infarcts, partial or complete third nerve paresis was combined with supranuclear gaze disturbance and delayed contralateral tremor. An unusual gaze disorder, a variant of the vertical "one-and-a-half syndrome," occurred with a small strategically placed lesion at the thalamopeduncular junction, best explained by selective damage to supranuclear pathways or partial nuclear involvement. The primary cause of these infarctions was embolism to the basilar apex or local atheroma at the origin of the posterior cerebral artery.
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PMID:Paramedian thalamopeduncular infarction: clinical syndromes and magnetic resonance imaging. 151 Mar 56

The intracranial cerebral circulation was studied in 6 patients with bilateral ischemic lesions due to lesions of the internal carotid artery in the extracranial segment (2 significant bilateral stenosis cases; 1 case with bilateral thrombosis and 3 cases of unilateral thrombosis and significant controlateral stenosis). All the patients were males their age ranging between the 5th and 8th decades of life. In a single case, the neurological examination showed secondary left hemiplegia and recent right paresis of remittent type whereas the other 5 patients had only transient ischemic attacks with hemiparesis or transient aphasia. The lesions were revealed by duplex system echotomography (Aloka-Hellige Model SSD-630) and spectral analysis of Doppler signal (Vasoscan-Sonicaid) and were later confirmed by bilateral carotid arteriography in all patients. The intracranial circulation was also watched by noninvasive methods using the spectral analysis of the Doppler signal with pulsed wave on TC-2 64-B apparatus. As for the modalities of blood flow compensatory mechanisms by the circle of Willis, it may be noted that in none of the patients investigated did the collateral supply observe a "mathematical model".
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PMID:Modalities of collateral supply of cerebral circulation through the circle of Willis in stenoses and occlusions of extracranial carotid arteries. 163 3

We reported a 62-year-old male with cerebral thrombosis presenting global aphasia without hemiparesis. The patient had an episode of aphasia 15 years ago, but recovered within 6 months. This time he had transient right sided mild hemiparesis, then he became aphasia next morning. When we examined at day 10 and day 15, his consciousness was clear, nothing he could speech, he could not understand or repeat. We diagnosed him global aphasia, but he had no hemiparesis except for right facial mild paresis and was able to walk. CT scan showed low density area in left and right posterior, left anterior watershed and left terminal zone. Cerebral angiography disclosed thrombotic occlusion of main trunk of left middle cerebral artery, and ambient segment of right posterior cerebral artery. Global aphasia without hemiparesis has been said a sign of embolic encephalopathy. This case was considered a very rare case, because he revealed global aphasia without hemiparesis by thrombotic occlusion.
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PMID:[A case of cerebral thrombosis presenting global aphasia without hemiparesis]. 169 61

A retrospective investigation was undertaken to investigate which factors are of significance in recommendation of patients with cerebral apoplexy in geriatric departments to nursing homes. The investigation includes 116 patients admitted during a period of two years. Thirty-five (30%) were recommended for nursing homes. Sixty-seven (58%) remained severely handicapped (corresponding to Rankin's groups IV and V). Logistic regression analysis revealed that marital status, dementia, lack of motivation and inability to walk were associated with recommendation for nursing homes whereas sex, degree of paresis, aphasia, focal cognitive disturbances, incontinence of urine and hemianopsia did not show any association. Sex was, similarly, of no significance for the functional result of rehabilitation. On the basis of the regression analysis, the probability of recommendation to a nursing home may be calculated with knowledge of the predisposing factors in any given patient.
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PMID:[Referral of elderly patients with cerebral apoplexy to nursing homes]. 239 77

In 10 out of 63 patients with intracerebral haematomas treated conservatively the authors measured approximately the volume of haematomas by means of serial CT examinations during observation of their resorption. These were large and medium-size haematomas, from 20 to 70 ml in volume. The mean rate of resorption was from 0.7 to 1.0 ml daily. Gradual regression of mass effects was noted. All patients were on admission in a relatively good condition, conscious or only somnolent, with focal neurological signs. In some cases signs of increased intracranial pressure were present. Improvement of the general condition and neurological status was relatively rapid, even pronounced paresis and aphasia regressed in most cases. Two patients (3%) died of non-cerebral causes. It is believed that most intracerebral haematomas may be treated conservatively. The presence of mass effects, increased intracranial pressure or even a major neurological syndrome are not regarded as indications to operation if the state of consciousness is good and is not deteriorating. Even large and deeply situated haematomas may be resorbed without leaving a gross neurological deficit. A careful observation of the state of the patient, control CT investigations and the possibility of carrying out emergency operation in case of deterioration of the level of consciousness are indispensable for safe conservative treatment of these patients.
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PMID:[Conservative treatment of intracranial hematomas and the dynamics of their resorption]. 258 5


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