Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A variety of alexia has been demonstrated that can be distinguished from the two classically recognized types of alexia. This reading disorder is seen in patients with a dominant frontal lobe pathologic condition that has produced a motor language disturbance (Broca aphasia) and is sufficiently disabling to deserve consideration as a variety of alexia. Functionally, the frontal reading disturbance differs from the other two types in that the patient comprehends meaningful content words better than relational or syntactic structures. Four factors that may underly frontal alexia have been noted: (1) gaze paresis, (2) inability to maintain verbal sequences; (3) inability to comprehend syntactic structure, and (4) literal alexia.
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PMID:The third alexia. 86 Sep 35

A 69-year-old, right-handed, Japanese male patient presented with pure agraphia with topographical disorientation after hemorrhage in the right parietal lobe. Upon developing cerebral hemorrhage, he was referred to our hospital for close examination of agraphia. There was no paresis or clumsiness in his extremities. His speech was fluent and well-articulated. Neither aphasia nor reading impairments was found, although there was a clear writing impairment with effort and hesitation. His writing of both kanji and kana letters contained additional, absent or deformed strokes or parts. No hemianopia, prosopagnosia, constructional disturbances and dressing apraxia were found. He could recognize familiar buildings or landscapes, but often lost his way around well-known areas. MR images revealed subcortical lesions of precuneus, superior and inferior parietal lobules in the right hemisphere, around the posterior horn of the lateral ventricle. He revealed pure agraphia and topographical disorientation after the right brain haemorrhage, without dementia or personality change. These findings indicate that the right parietal lobe participates in the kinesthetic movements of writing. Some authers have been documented cases of aphasic agraphia or alexia with agraphia caused by right hemisphere damage in dextrals, but pure agraphia caused by the lesion in the right hemisphere is very rare.
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PMID:[Pure agraphia with topographical disorientation caused by right hemisphere lesion]. 1871 86

Abstract A 69-year-old right-handed man developed alexia with agraphia after resection of a brain tumor in the left parietal lobe. After the operation, neurological examination revealed right lower quadrantanopia, mild paresis and sensory disturbance on the right side. He showed marked alexia with agraphia, very mild aphasia, acalculia, and constructional disability. In reading tasks, he was able to read kanji word and kana words but not a single kana character or nonword. After he traced a single kana character or kana nonword, he was able to read it. In writing tasks, he could write kana but not kanji characters, except simple kanji characters that involved less than 4 strokes. These findings indicated that kinesthetic traces may enable such patients to read and write. We propose that processes of reading and writing may include kinesthetic route in addition to the meaning, phonological, and orthographical routes.
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PMID:[Meaning, phonological, orthography and kinestic route of reading and writing: a case with alexia and agraphia due to the left parietal lesion]. 2084 10