Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030305 (pancreatitis)
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Human Gene/Protein
protein disulfide isomerase-associated 2 11.0
CTRL protein 11.0
CCDC132 11.0
protease serine 1 10.6
cationic trypsinogen 10.2
PRSS1 10.2
RIPPLY1 10.0
PDA2 9.4
ACTB protein 9.4
dnaK-type molecular chaperone 9.4
FRMD4 9.4
ECRP 9.4
PRSS2 9.3
CTRC 9.3
elastase 2A 9.2
pancreatic secretory trypsin inhibitor 9.1
Pancreatic elastase 9.1
PAP-I 9.0
RAB6B 9.0
minichromosome maintenance complex component 3 9.0
pancreatitis-associated protein 8.9
trypsinogen 8.9
lipase maturation factor 1 8.9
ATP6V1D 8.6
ATP synthase 8 8.5
CTFR 8.5
PSTI 8.5
anionic trypsinogen 8.5
lithostathine 8.4
PCPB 8.4
RAB8B 8.4
trypsinogen 4 8.4
MORC4 8.4
fucosyltransferase 3 8.4
expressed in pancreatic carcinoma 8.4
LMF1 8.3
marapsin 8.2
5-hydroxytryptamine (serotonin) receptor 2C 8.2
elastase 3B 8.2
RABL2A 8.2
HO68 8.2
Mis5 8.2
elastase 1 8.0
AIP2 8.0
FRMD4B 8.0
PAPOLA 8.0
REG III 8.0
mesotrypsinogen 8.0
INGAP 7.9
pancreatic stone protein 7.8
Adapter protein 7.8
REG1B 7.8
RAB26 7.8
amylase 7.7
VMP1 7.7
pancreatic elastase 1 7.7
serine protease 1 7.7
mesotrypsin 7.7
PAP-II 7.6
S100 calcium binding protein P 7.6
CPA1 7.6
MIST1 7.5
WWC2 7.5
synaptosomal-associated protein 23 7.5
RAB32 7.5
RABL2B 7.5
GKD 7.5
CELP 7.5
GPIHBP1 7.4
ATP6V1H 7.4
FAP protein 7.4
APOC2 7.4
CBL-B 7.3
CTRB1 7.3
ABCF1 7.2
MPPED2 7.2
CPSF1 7.2
KIAA1967 7.2
AIP-1 7.2
apolipoprotein A-V 7.1
more...
Disease
Aneurysm of gastroduodenal artery 11.0
Ischemic pancreatitis 11.0
Other chronic pancreatitis 11.0
Pancreatic haemorrhage 11.0
Benign islet cell tumor 11.0
Chronic fibrosing pancreatitis 11.0
Interstitial pancreatitis 11.0
pancreatitis 11.0
Pancreatic and peripancreatic necrosis 11.0
Necrotizing panniculitis 11.0
Stomach obstruction 11.0
Pancreatic phlegmon 11.0
Idiopathic chronic pancreatitis 11.0
Hemorrhagic conjunctivitis 11.0
EC cell carcinoid 11.0
Idiopathic acute pancreatitis 10.6
Edematous pancreatitis 10.5
Gallstone pancreatitis 10.5
Hemorrhagic pancreatitis 10.5
Chylomicronemia syndrome 10.4
Obstructive chronic pancreatitis 10.4
Acute necrotizing pancreatitis 10.3
Acute and chronic pancreatitis 10.3
Infected pancreatic necrosis 10.2
Acute recurrent pancreatitis 10.2
Sump syndrome 10.2
Drug-induced acute pancreatitis 10.2
Hereditary chronic pancreatitis 10.1
Acute intestinal pseudo-obstruction 10.0
Basal pneumonia 10.0
mumps pancreatitis 10.0
Peripancreatic necrosis 10.0
Pancreatic duct stricture 10.0
Pancreatic enlargement 10.0
Duodenal necrosis 10.0
Subacute myocarditis 10.0
Courvoisier's gallbladder 10.0
alcoholic pancreatitis 9.8
Pancreatic necrosis 9.8
pancreatic abscess 9.7
acute pancreatitis 9.7
Sphincter of Oddi dysfunction 9.7
Pancreatic pseudocyst 9.7
Hyperamylasemia 9.5
Splenic vein thrombosis 9.5
Pancreatolithiasis 9.4
Renal proteinuria 9.4
Acute nephropathy 9.4
Dry beriberi 9.4
Carcinoid tumor of the pancreas 9.4
Adenoma and adenocarcinoma 9.4
Cholangiohepatitis 9.4
pancreolithiasis 9.4
Choledochocele 9.2
Pancreatic ascites 9.2
Cholecystitis and cholelithiasis 9.2
Eruptive xanthomas 9.2
head neoplasm 9.2
chronic pancreatitis 9.1
Pancreatic duct 9.0
Lactobacillus infection 9.0
Duodenal disease 9.0
Suppurative cholangitis 9.0
Lupus hepatitis 9.0
choledochitis 9.0
Splenic hemorrhage 9.0
Drug-induced hypoglycaemia 9.0
Inferior vena cava stenosis 9.0
Recurrent cholangitis 9.0
Iodine allergy 9.0
Diabetic gastropathy 9.0
pancreatic fibrosis 8.9
Pancreatic duct obstruction 8.8
Secondary hyperlipidemia 8.8
Macroamylasemia 8.7
Hypocalcemic tetany 8.6
Epstein-Barr viremia 8.6
Calculous cholecystitis 8.6
Hemorrhagic pleural effusion 8.6
Chronic cholangitis 8.6
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Symptom
Malaise and fatigue 11.0
Hepatocellular jaundice 11.0
Drug-induced xerostomia 11.0
Pancreatic pain 10.5
Right hypochondrial pain 10.0
pain in the umbilical region 10.0
abnormal bruising 9.0
digestive problem 9.0
Cullen's sign 8.9
autodigestion 8.7
Kehr's sign 8.6
decreased bowel sounds 7.5
Intermittent fever 7.3
gastrointestinal gas 7.1
epigastric pain 7.0
Organ failure 7.0
swollen scrotum 6.9
GI pain 6.7
Upper abdominal pain 6.6
Visceral pain 6.4
intestinal pain 6.4
right upper quadrant pain 6.3
abdominal pain 6.3
Localized pain 6.3
Osler's nodes 6.3
acute abdominal pain 6.2
Murphy's sign 6.0
localized erythema 6.0
Abdominal tenderness 6.0
generalized abdominal pain 5.9
intestinal angina 5.9
Tissue sensitivity 5.8
breast hyperplasia 5.8
acute abdomen 5.7
ketonuria 5.7
left upper quadrant pain 5.5
Urticarial vasculitis 5.5
musculoskeletal disability 5.4
stomach cramps 5.4
koilonychia 5.3
No pain 5.2
Chronic abdominal pain 5.1
abdominal cramps 4.9
renal pain 4.9
abdominal discomfort 4.9
hyperemesis gravidarum 4.7
vomiting 4.6
Gastrointestinal symptoms 4.6
colic 4.5
hyperemesis 4.3
abdominal fullness 4.3
nerve pain 4.2
Physical findings 4.2
nausea 4.1
hypoproteinemia 4.1
prostration 4.0
bloating 3.8
dark urine 3.8
oliguria 3.8
nausea and vomiting 3.7
polydipsia 3.7
anorexia 3.6
physical exhaustion 3.6
acid regurgitation 3.6
polyuria 3.6
livedo 3.5
testicular pain 3.5
emaciation 3.5
Flare 3.5
lethargy 3.4
Neurologic symptoms 3.4
splenomegaly 3.4
decreased appetite 3.4
aphagia 3.4
flank pain 3.3
intestinal bleeding 3.3
renal colic 3.3
belching 3.3
abnormal breathing 3.2
inanition 3.2
more...
Drug
Oragrafin calcium 11.0
Lexipafant 9.2
Pro-Banthine 9.1
E.E.S. 9.0
Gabexate mesilate 8.5
Camostat mesilate 8.5
Tripamide 8.0
Caraway 7.8
Loxiglumide 7.8
Nafamostat mesilate 7.8
Ulinastatin 7.7
Oncaspar 7.6
Bindarit 7.4
Pegaspargase 7.4
Fialuridine 7.4
Asparaginase 7.3
Januvia 7.3
Edetate disodium 7.1
Compazine 6.9
L-Asparaginase 6.7
Dazmegrel 6.6
CFPM 6.6
Garamycin 6.5
Garamycin 6.4
Hetrazan 6.4
Compazine 6.4
ddI 6.3
Bisolvon 6.2
Prostigmin 6.1
Sandostatin 6.0
Sandostatin 6.0
Hexabrix 320 6.0
Metolazone 6.0
LMOX 6.0
Sodium thiosulfate 5.9
Garamycin 5.8
Liraglutide 5.8
Arduan 5.7
Mercaptopurine 5.6
Ocrelizumab 5.6
Secretin 5.5
Epivir 5.5
Exenatide 5.4
Aprotinin 5.4
Paraplatin 5.4
Platelet Activating Factor 5.4
Pancreatin 5.2
Proglumide 5.0
OctreoScan 5.0
Maalox 4.9
Beraprost sodium 4.9
Gemfibrozil 4.9
Dextran sulfate sodium 4.9
Keppra 4.9
Pramlintide 4.9
Amoxapine 4.9
Ceruletide 4.8
Tegaserod 4.8
Timentin 4.8
Propentofylline 4.6
Pentostam 4.6
Omniscan 4.6
Tegaserod 4.5
Sandostatin LAR 4.5
Anagrelide 4.5
Cidofovir 4.5
Emodin 4.4
Ovulen 4.4
Emodin 4.4
Mizoribine 4.4
Imuran 4.3
Bactrim 4.3
Ipilimumab 4.3
Prednisone 4.3
Lipiodol 4.3
Mirtazapine 4.3
Gelfoam 4.2
Nexavar 4.2
Sodium valproate 4.2
Aztec 4.2
more...
Enzyme
chymotrypsin C 9.7
isoamylase 7.4
L-fucose dehydrogenase 7.4
CYP39A1 6.8
lipase 6.4
enterokinase 6.4
asparaginase 6.3
EPT 5.6
thiopurine methyltransferase 5.4
cathepsin B 5.4
CBPP 5.3
beta-D-fucosidase 5.0
lipoprotein lipase 4.8
trypsin 4.7
histidase 4.7
ADH3 4.5
elastase 4.5
LPL 4.2
LMT 4.2
2A protease 4.1
alpha-amylase 4.1
CYP7B1 4.0
asparagine synthetase 4.0
C3b inactivator 3.9
methylmalonyl-CoA mutase 3.9
S-adenosyl-L-homocysteine hydrolase 3.9
phospholipase A2 3.9
tissue kallikrein 3.8
CGT 3.8
prostasin 3.7
lactic acid dehydrogenase 3.7
carboxypeptidase B 3.7
deoxyhypusine synthase 3.7
STK11 3.7
lactic acid dehydrogenase 3.6
chymotrypsin 3.6
kallikrein 3.4
neutrophil elastase 3.3
aminopeptidase P 3.2
aminopeptidase B 3.2
glycerol dehydrogenase 3.1
glycerol dehydrogenase 3.1
3-mercaptopyruvate sulfurtransferase 3.1
phosphomannomutase 3.1
lactic acid dehydrogenase 3.0
caspase-2 3.0
TGT 2.9
caspase-2 2.9
xanthine oxidase 2.8
cathepsin L 2.8
diacylglycerol acyltransferase 2.8
gamma-glutamyl transpeptidase 2.6
ribonuclease 2.6
ribonuclease 2.6
beta-glucuronidase 2.6
propionyl-CoA carboxylase 2.5
methionine adenosyltransferase 2.5
propionyl-CoA carboxylase 2.5
caspase-11 2.5
diamine oxidase 2.5
caspase-11 2.5
E-2 2.5
AST 2.5
alpha-L-fucosidase 2.4
catechol 1,2-dioxygenase 2.4
legumain 2.4
cathepsin C 2.4
alanine aminotransferase 2.3
aspartate aminotransferase 2.3
alkaline phosphatase 2.3
phospholipase A1 2.3
peroxidase 2.3
lactate dehydrogenase 2.2
DNase II 2.2
ALDH 2.1
polyamine oxidase 2.1
tryptase 2.1
cholesterol esterase 2.1
deoxyribonuclease 2.0
3C protease 2.0
more...
Compound
Asperlicin 8.6
Di-n-butyltin dichloride 8.5
Didanosine 8.2
Bilopaque 8.0
Dunnione 7.8
Sennoside 7.8
Glycodeoxycholate 7.4
Hexamethyldisiloxane 7.3
Visnagin 7.3
Compazine 7.1
Stains-all 6.5
HM-4 6.5
Thiocolchicoside 6.4
MMPR 6.4
3,4-D 6.3
Neoprene 6.2
Azodicarbonamide 6.2
Potassium bromide 6.1
EDAP 6.1
Gentiopicroside 6.0
6-Keto-PGF1a 5.9
Olsalazine 5.8
C6H8O7 5.8
1-methylpyrrolidine 5.8
Norethisterone acetate 5.7
Trimethadione 5.7
Oxypurinol 5.7
PAMBA 5.6
Azathioprine 5.6
Octreotide 5.6
Taurocholate 5.6
Salicin 5.5
Salicin 5.5
HM-3 5.5
Secretin 5.5
Lubiprostone 5.4
Valproic acid 5.4
SC-58125 5.4
Daphnetin 5.3
Clindamycin phosphate 5.3
Pentamidine 5.3
Tanakan 5.3
Ethionine 5.2
3-Deazaneplanocin 5.2
Telepaque 5.2
Dithizone 5.1
TCAP 5.1
Grepafloxacin 5.1
Guggulsterone 5.0
Meglumine 4.9
Vidarabine 4.8
Methylmalonic acid 4.8
Cucurbitacin B 4.7
Solu-Medrol 4.7
Z-Gly-Pro 4.7
Carbimazole 4.7
cephalotaxine 4.6
Cromolyn 4.6
Cidofovir 4.6
propionyl-coenzyme A 4.5
Resiniferatoxin 4.5
Cypridina luciferin 4.5
Ursodeoxycholic acid 4.5
cephalotaxine 4.5
Homoharringtonine 4.4
Emodin 4.4
PTMA 4.4
Mesalamine 4.4
Calcium carbonate 4.4
Diazinon 4.3
PSP 4.3
PEP 4.3
Trypsin 4.3
Danshensu 4.3
Diatrizoate 4.2
Diatrizoate 4.2
Reticulin 4.2
Chenodeoxycholic acid 4.2
DPP 4.1
Ethyl pyruvate 4.1
more...