Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0030305 (
pancreatitis
)
16,014
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Three radioimmunoassays (RIA) for the pancreas specific proteins TLI,
PASP
and CA 19-9 were evaluated in serum from normal control dogs (n = 40) and dogs with
pancreatitis
(n = 20). Statistically significant differences (P < 0.05) were found for serum TLI and
PASP
levels between the control and
pancreatitis
groups. However, only 3/20 dogs with
pancreatitis
had serum TLI concentrations greater than the highest concentration in control dogs. Concentrations of
PASP
in serum were higher in 15/20 dogs with
pancreatitis
than in the control dogs. The magnitude of the increase in concentrations of
PASP
in
pancreatitis
was small in the majority of cases. Thus these assays are of limited clinical value in the diagnosis of
pancreatitis
. There was no cross-reactivity with dog serum in the CA 19-9 assay.
...
PMID:Evaluation of three pancreas specific protein assays, TLI(trypsin-like immunoreactivity), PASP (pancreas specific protein) and CA 19-9 (glycoprotein) for use in the diagnosis of canine pancreatitis. 928 36
