Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study was undertaken in order to compare the reliability of two acute reflux pancreatitis models in rats, one performed by positioning a silicon tube in the duodenum and the other by creating a gastro-jejunal anastomosis. In two groups (A = 10 and B = 10 rats) a silicon tube was positioned in the duodenum; in the remaining two groups (C = 12 and D = 6 rats) a latero-lateral antecolic anisoperistaltic gastro-jejunal anastomosis was performed 30 days before surgery. A closed duodenal loop was created for 12 hours in groups A and C but not in B and D. Rats in both groups A and C developed acute pancreatic inflammation of a mild degree. Sham operated rats with silicon tube placement had higher histological damage scores than those with gastro-jejunal anastomosis. The difference found between the two groups of rats which underwent gastro-jejunal anastomosis was more marked than that between the two groups which had silicon tube placement. It was concluded that the creation of a gastro-jejunal anastomosis is probably the safer procedure to allow gastro-intestinal flow in acute reflux pancreatitis in rats.
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PMID:Acute reflux pancreatitis in rats: a comparison between two experimental models. 138 50

For last 12 years 455 patients with an acute pancreatitis were treated in the clinic. In 29 (6.3%) of them purulent pancreatitis, originating from pancreonecrosis, was diagnosed. Operative intervention consisted of laparotomy conduction, bursa omentalis draining through lig, gastrocolicum, excision of purulent-necrotic foci in pancreas and retroperitoneal fat, draining purulent cavity using two silicon tubes, introduced via left and right epigastral regions, durable lavage of purulent cavity with antiseptic solutions. Five patients died.
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PMID:[Purulent pancreatitis]. 1037 Mar 7