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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection was treated in an 8-year-old girl. She experienced acute pancreatitis during treatment for M. pneumoniae. Contrast-enhanced computed tomographic scan revealed necrotizing pancreatitis. The computed tomographic severity index was 8 points (grade E). A protease inhibitor, ulinastatin, was provided via intravenous infusion but was ineffective. Continuous regional arterial infusion therapy was provided with gabexate mesilate (FOY-007, a protease inhibitor) and meropenem trihydrate, and the pancreatitis improved. This case suggests that infusion therapy is safe and useful in treating necrotizing pancreatitis in children.
Cardiovasc Intervent Radiol 2009 May
PMID:Continuous regional arterial infusion therapy for acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection in a child. 1895 23

Orbital atherectomy represents a newly developed technology for the endovascular treatment of peripheral artery disease. There is currently limited data with regards to the safety and efficacy of this treatment. Herein, we describe a case where orbital atherectomy was utilized to treat a heavily calcified superficial femoral artery, and describe a previously unreported side effect of orbital atherectomy, hemolysis induced pancreatitis.
Catheter Cardiovasc Interv 2008 Dec 01
PMID:Hemolysis induced pancreatitis after orbital atherectomy in a heavily calcified superficial femoral artery. 1902 Dec 78

Glucocorticoids are used as anti-inflammatory agents and are associated with many side effects including hyperglycemia, hypertension, pancreatitis, peptic ulcer, and so on. Hyperglycemia is a common side effect, but ketoacidosis is observed rarely. We present a girl who developed diabetic ketoacidosis after the administration of methylprednisolone during the treatment of acute rheumatic fever. She did not have diabetes and was not obese. She developed ketoacidosis after glucocorticoid therapy. Glucocorticoid-induced insulin resistance, lipolysis, and ketogenesis were likely to have precipitated ketoacidosis. During the treatment of ketoacidosis, the insulin need of the patient was gradually decreased by reducing glucocorticoid dose. In addition to the gradual reduction in glucocorticoid dose, salicylate therapy could be considered the treatment for insulin resistance. In this patient, screening for blood gases and urine was diagnostic in the diagnosis of ketoacidosis. The risk of ketoacidosis as well as hyperglycemia should be considered in the course of glucocorticoid therapy.
J Cardiovasc Pharmacol Ther 2008 Dec
PMID:Glucocorticoid-induced diabetic ketoacidosis in acute rheumatic fever. 1908 51

Cardiac surgery is commonly associated with gastrointestinal complications. The incidence of severe abdominal pathology ranges from 0.5% to 3% and is associated with a 30% risk of mortality. Frequently occurring complications include splanchnic infarction, perforated bowel, pancreatitis, upper intestinal bleeding and diverticulitis. Systemic and localised infections are also common after open heart surgery. Plasma proteins, neutrophils, monocytes, endothelial cells and lymphocytes are all altered by cardiopulmonary bypass (CPB). Cell mediated immunity is depressed following exposure to the extra-corporeal circuit leading to an increased susceptibility and vulnerability to pathogens. Typhoid fever is the systemic manifestation of Salmonella typhi septicaemia. Its presentation can be similar to that of abdominal ischaemia making the diagnosis of this potentially fatal multi-systemic illness challenging. We report a fatal case of salmonella septicaemia convincingly masquerading as mesenteric ischaemia following routine CPB.
Interact Cardiovasc Thorac Surg 2011 Feb
PMID:Salmonella sepsis simulating gastrointestinal ischaemia following cardiopulmonary bypass. 2110 65

An adolescent female was admitted to the pediatric intensive care unit in septic shock. She developed multisystem organ dysfunction including pancreatitis with myocardial dysfunction and hemodynamic instability unresponsive to medical management necessitating veno-arterial extracorporeal support. Streptococcus Constellata and Fusobacterium necrophorum were isolated from blood cultures. This is the first report of extra-corporeal cardiac support in fusobacterium sepsis.
Ann Thorac Cardiovasc Surg 2011
PMID:Extra-corporeal membrane oxygenation in a patient with Fusobacterium sepsis: a case report and review of literature. 2188 29

Abdominal complications following cardiac surgery remain unusual, but are associated with high mortality. The most common abdominal surgical complications are mesenteric ischaemia, diverticulitis, pancreatitis, gastrointestinal bleeding and cholecystitis. We describe a case of a 73-year old woman with acute abdominal pain mimicking cholecystitis on day 10 after aortic valve replacement. An abdominal examination showed tenderness of the right upper quadrant with Murphy's sign. Complete blood count, blood chemistries and urinalysis were normal as were the abdominal and chest X-rays and abdominal ultrasonography. The abdominal computed-tomography (CT) scan enabled us to rule out cholecystitis, as it demonstrated the typical appearance of epiploic appendagitis on the right colon, 1 cm below the gallbladder. Epiploic appendagitis results from twisting, kinking or venous thrombosis of an epiploic appendage. Depending on its localization, it mimics many diagnoses requiring surgery: colitis, diverticulitis, appendicitis and cholecystitis. An abdominal CT scan is the diagnostic imaging tool of choice. All physicians involved in post-cardiac surgery care should be aware of this self-limiting disease that usually resolves with non-steroidal anti-inflammatory drugs and watchful waiting, and to avoid unnecessary surgery because the spontaneous evolution of epiploic appendagitis is usually benign.
Interact Cardiovasc Thorac Surg 2012 Aug
PMID:An unusual cause of acute abdominal pain after cardiac surgery: acute epiploic appendagitis. 2254 60

Acute respiratory distress syndrome (ARDS) poses a major challenge in intensive care settings. The main underlying causes of ARDS are trauma, pancreatitis, and pulmonary manifestation of systemic inflammatory response syndrome/sepsis.Lemierre syndrome represents a nearly forgotten entity arising from oropharyngeal infections with Fusobacterial species, and it is of renewed and increasing interest because of evolving antibiotic resistances.We report two cases of young female patients afflicted by Lemierre syndrome with additional severe ARDS and present an overview of the current literature.
Thorac Cardiovasc Surg 2013 Dec
PMID:Severe ARDS induced by fusobacterial infections: a rare clinical presentation of Lemierre syndrome. 2356 39

The most severe complication of ischemia-reperfusion injury following lower limb arterial surgery is reperfusion syndrome. Therefore, our aim was to describe the extent of muscle damage and the reperfusion syndrome-related remote organ lesions in detail, through a well-documented case of long-lasting infrarenal aorta thrombosis. After urgent revascularization, several clinical signs of multiple organ dysfunction were detectable, including the circulatory, urinary, respiratory, gastrointestinal, and hemostatic systems. Upon histological examination, intraoperative muscle biopsy showed severe muscle damage. Muscle fiber viability was assessed with a special nitroblue tetrazolium staining-based viability test developed by our team; the obtained results indicated significant degree of muscle damage before this was confirmed by conventional histological methods. Thorough postmortem examination confirmed the presence of remote organ damage. The pathological findings included acute tubular necrosis, myocardial and jejunal infarctions, ischemic pancreatitis, and diffuse alveolar damage with hyaline membrane formation in the lungs and focal centrilobular liver necrosis. By using special staining techniques, the presence of myoglobin and lipofuscin deposits was confirmed in the kidney samples. In this paper, we present a patient who developed all major complications following long-lasting arterial occlusion. We also introduce a novel method to assess the degree of ischemic injury, which may be suitable in the near future for the rapid detection of irreversible muscle injury. Therefore, the mortality of the disease might be reduced.
Cardiovasc Pathol
PMID:Rapidly progressing fatal reperfusion syndrome caused by acute critical ischemia of the lower limb. 2385 Jan 81

Pleuropulmonary complications of pancreatitis are well known. Less commonly encountered is pancreaticopleural fistula. We describe the case of a 15-year-old boy with a presumed episode of pancreatitis, complicated by pseudocyst and development of a pancreaticopleural fistula. Successful medical management was achieved, and he made a full recovery. This case demonstrates that the rarity of such a condition leads to delay as well as challenges in diagnosis and management.
Asian Cardiovasc Thorac Ann 2014 Jan
PMID:Pancreaticopleural fistula: an overlooked entity. 2458 55

A 41-year-old male smoker presented with choking and coughing up food associated with repeated vomiting. Four years previously, following recurrent episodes of pancreatitis, he required percutaneous necrosectomy. He subsequently had a cholecystectomy and mesh repair of the abdominal wall, and later developed multiple problems including a gastrobronchial fistula. Computed tomography revealed a fistulous connection for which he had a combined procedure. Through a thoracolaparotomy approach, the left lower lobe and fistulous connection were removed along with the surrounding diaphragm and the associated fundus of the stomach. The diaphragm defect was repaired without mesh.
Asian Cardiovasc Thorac Ann 2014 Oct
PMID:Management of a rare gastrobronchial fistula following recurrent pancreatitis. 2488 78


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