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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clonorchis sinensis is an aften-cited but rarely reported cause of acute pancreatitis. We report a patient with Clonorchis infestation detected 24 years after leaving the endemic area, in whom the parasite is a likely cause of pancreatitis. Recognizing the popularity of the Cantonese style of Chinese cooking and noting relaxation of travel restrictions to the endemic areas, we feel Clonorchis should be sought in the obscure case of pancreatitis, especially in Orientals and travelers who have lived in the endemic area.
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PMID:Clonorchis sinensis and pancreatitis. Twenty-five after endemic exposure. 110 42

Infection with 100 Opisthorchis viverrini (OP) metacercariae prior to two injections of dihydroxy-di-n-propyl nitrosamine (DHPN) (1000 mg/kg body weight) brought about significant enhancement of resultant preneoplastic lesion development in Syrian hamster liver and pancreas tissue. Thus combined treatment with carcinogen and parasite was associated with pancreatic atypical (dysplastic) foci, hepatocellular nodules, cholangiofibrosis and cholangiocarcinomas. No such lesions were observed in carcinogen alone, parasite alone or untreated control groups. In addition, parasite induced hyperplastic gall bladder epithelium was found to include areas of putative preneoplastic cells only in the DHPN-OP combined group. The results strongly suggest that pancreatitis and biliary cirrhosis associated with liver fluke infestation are responsible for the observed enhancement of carcinogenesis, and that the resultant increased proliferation plays a major role in tumorigenesis.
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PMID:Enhancement of DHPN induced hepatocellular, cholangiocellular and pancreatic carcinogenesis by Opisthorchis viverrini infestation in Syrian golden hamsters. 283 5

Cholangitis and pancreatitis have resulted from migration of Ascaris lumbricoides up the biliary tree. We report our experience with the endoscopic management of 11 patients who presented with cholangitis and pancreatitis. Successful endoscopic worm extraction with or without sphincterotomy was achieved for worms located in the biliary tree but endoscopic worm extraction from the pancreas was technically difficult. Anthelminthic therapy is indicated to eradicate the gut infestation and prevent recurrent disease.
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PMID:Endoscopic management of biliary ascariasis. 341 Feb 42

Clonorchis Sinensis infestation can involve the pancreatic duct and induce attacks of acute pancreatitis. Ct findings in a case of Clonorchis Sinensis pancreatitis revealed significant enlargement of the pancreas with compression and obstruction of the common duct. Medical treatment leads to resolution of the clinical and CT findings. The patient experienced a second episode of pancreatitis 3 yr later. CT examination documented the development of chronic pancreatitis with an acute exacerbation.
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PMID:CT of Clonorchis Sinensis pancreatitis. 828 82

The most common infection of the hepatobiliary system and of the pancreas is the infestation with Ascaris lumbricoides. Pancreatobiliary ascariasis may present as recurrent biliary colic, acalculous cholecystitis, cholangitis, pancreatitis, or hepatic abscess. Although ultrasonography is a highly sensitive and specific method for the detection of the disease, endoscopy may have also therapeutical potential. The majority of these infections is registered in developing countries, but the number of reports from Europe and North America is increasing. So far there has not been any publication from Hungary. Both of the two reported patients were admitted the hospital with colic pain in the right hypochondrium. The laboratory parameters revealed cholestasis. The transabdominal ultrasonography was normal in one case, but suspected alien body in the choledochus in the other patient. Ascaris lumbricoides was identified with endoscopic procedure in the ductus choledochus in both cases. Endoscopic extraction of the worm resulted in cessation of the complaints in both patients, their cholestatic laboratory parameters became normal. Although the parasitic tests in the stool were negative in both patients and in their relatives, mebendazole therapy was administered.
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PMID:[Endoscopic treatment of cholestasis caused by Ascaris lumbricoides]. 1133 72

Pancreatitis is under appreciated during childhood although its diagnosis is simple and management straightforward in most cases. There is a range of possible causes, which is quite different to the situation in adults. The commonest underlying problems are probably structural abnormalities of the pancreatic and biliary ducts such as choledochal malformation, common pancreatobiliary channel and pancreas divisum. Other causes, which can be important in certain groups and geographical areas, are those due to drug reactions, viral infection and parasitic infestation, and blunt abdominal trauma. The diagnosis is established by showing a significantly raised plasma amylase level. Other diagnostic tools such as ultrasound, computed tomography (CT) scanning and endoscopic retrograde cholangiopancreatography (ERCP) have a major role in determining possible underlying causes, and hence selecting out those who require definitive corrective surgery. The pathophysiology of pancreatitis remains to be fully elucidated and, in the acute phase can affect other organs such as the renal and respiratory systems. Later complications include sepsis, pancreatic abscess and typically pseudocyst formation. Most of these can be treated using minimally invasive techniques such as percutaneous aspiration although open surgical techniques such as cystgastrostomy may be required in a few.
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PMID:Acute and chronic pancreatitis. 1242 Sep 14

Jaundice and pancreatitis are serious complications in post renal transplantations; hepatotropic viruses and drugs are commonly implicated. We describe ascaris infestation causing pancreatitis and obstructive jaundice in a renal transplant patient.
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PMID:Ascariasis as a cause of obstructive jaundice in a renal transplant patient. 1536 70

It is a prospective study was done in the department of surgery of Sher-E-Bangla Medical College hospital from September 2004 to June 2005. Twenty cases selected for the study. Among 20 cases 16 is female & 4 is male. The age range of the patient was between 20 years to 65 years. Ultrasonography is the main tool of diagnosis. ERCP is not available in this regional hospital. CT scan not done because it is expensive for the poor patient who are the mainly the subject in this study. Eighty percent (16) of the cases present with recurrent upper abdominal pain. Thirty percent (6) with acute Cholecystitis, 25% (5) with obstructive jaundice, 25% (5) with Cholangitis 5% (1) with mild pancreatitis, 5% (1) with perforation of hollow viscus and 5% (1) with hepatolithiasis. Seventy percent (14) of the cases treated conservatively 25% (5) cases have under gone routine elective operation and 5% (1) cases have under gone emergency operation. Females are the common victims (M:F-1:4). Provision of safe drinking water, regular deworming and improvement of personal hygiene can largely reduces the dreadful consequences due to infestation by worm.
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PMID:Varied presentation of biliary ascariasis and its consequences. 1687 95

Parasitic infestations of the biliary tract are a common cause of biliary obstruction in tropical countries and can lead to such serious complications as cholangitis and cholangiocarcinoma. Endoscopic therapy has helped in the management of biliary complications caused by these parasites. Ascaris lumbricoides organisms, which normally reside in the jejunum, are actively motile and can invade the papilla, thus migrating into the bile duct and causing biliary obstruction. Endoscopic retrograde cholangiopancreatography is a useful diagnostic tool with potential for therapeutic management of biliary ascariasis. Infestation with Clonorchis sinensis organisms can cause such complications as intrahepatic stones, recurrent pyogenic cholangitis, cirrhosis, cholelithiasis, pancreatitis, and cholangiocarcinoma. Opisthorchis viverrini, Opisthorchis felineus, and Dicrocoelium dendriticum are closely related to C. sinensis and can also cause serious biliary complications. Fascioliasis, caused by Fasciola hepatica and F. gigantica, is a zoonotic helminthiasis that can present as acute hepatic or chronic biliary tract infection. CT, MRI, and ultrasound guidance are useful imaging tools for identifying these parasites and their complications.
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PMID:Parasitic infestations of the biliary tract. 1741 62

A leading cause of biliary tract disease and pancreatitis worldwide is parasitic disease. In the United States, increased global travel and the AIDS epidemic has led to a rise in the frequency of parasitic disease. Biliary disease and pancreatic disease secondary to parasitic infestation is relatively new in this country, with the first case being described in 1977. These diseases are no longer the exclusive realm of infectious disease specialists and require general practitioners and gastroenterologists to be well versed in the spectrum of parasitic pancreatic and biliary disease.
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PMID:Parasitic causes of pancreatic and biliary tract disease: a growing concern in a highly mobile population. 2005 32


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