Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among 81 hospitalized patients with enteritis due to Campylobacter fetus ssp. jejuni, abdominal pain was found to be an outstanding symptom, being observed in half the patients on admission. In 16 patients pain was the main reason for admission and in 5 prompted laparotomy. In 4 cases appendicitis was suspected, but in only 2 was slight inflammation seen; in 1 of these, however, the inflammation could not be verified by microscopic examination. One patient was operated on because of intestinal occlusion, presumably due to Campylobacter enteritis. In 10 further cases a surgeon was consulted because the abdominal pains were at first suspected to be due to cholecystitis, pancreatitis or other abdominal emergencies. Thus, acute phase of Campylobacter infection may mimick acute abdominal emergency. The diagnosis is sometimes hampered by the late onset of diarrhoea or even by its total absence, as well as by the usual presence of abdominal tenderness and severe abdominal pains.
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PMID:Campylobacter enteritis mimicking acute abdominal emergency. 734 86

Campylobacter jejuni and Salmonella spp are the most frequently cultured micro-organisms in infectious gastroenteritis among patients hospitalized at the departments of gastroenterology and geriatrics. As a whole, the hospitalized patient population with Campylobacter gastroenteritis is a younger one, compared to the Salmonella-infected group. Both pathogens can be associated with a biochemical pancreatitis, which is usually without clinical importance. However, serious complications can occur, with a predominance of visceritis for C. jejuni, and renal function impairment for Salmonella spp. Finally, an asymptomatic carrier state is well known in the Salmonella infection spectrum, whereas C. jejuni might cause a recurrent disease in some patients.
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PMID:Infectious gastroenteritis: are they all the same? 853 26

A 25-year-old man was admitted with the chief complaints of right flank pain, watery diarrhea, and fever. Blood tests revealed high levels of inflammatory markers, and infectious enteritis was diagnosed. A stool culture obtained on admission revealed no growth of any significant pathogens. Conservative therapy was undertaken with fasting and fluid replacement. On day 2 of admission, the fever resolved, the frequency of defecation reduced, the right flank pain began to subside, and the white blood cell count started to decrease. On hospital day 4, the frequency of diarrhea decreased to approximately 5 times per day, and the right flank pain resolved. However, the patient developed epigastric pain and increased blood levels of the pancreatic enzymes. Abdominal computed tomography revealed mild pancreatic enlargement. Acute pancreatitis was diagnosed, and conservative therapy with fasting and fluid replacement was continued. A day later, the blood levels of the pancreatic enzymes peaked out. On hospital day 7, the patient passed stools with fresh blood, and Campylobacter jejuni/coli was detected by culture. Lower gastrointestinal endoscopy performed on hospital day 8 revealed diffuse aphthae extending from the terminal ileum to the entire colon. Based on the findings, pancreatitis associated with Campylobacter enteritis was diagnosed. In the present case, a possible mechanism of onset of pancreatitis was invasion of the pancreatic duct by Campylobacter and the host immune responses to Campylobacter.
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PMID:Case of acute pancreatitis associated with Campylobacter enteritis. 2496 23