Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Retroperitoneal abscess with multiple organ failure, after traumatic duodenal rupture followed by dehiscence of duodenal sutures, is a condition associated with a very high mortality. We report on a case treated by retroperitoneal laparostomy, a technique proposed as treatment for pancreatic abscess after an acute necrotizing pancreatitis. The retroperitoneal laparostomy creates a wide open cavity in a gravity-favorable position, allowing drainage and daily debridement of necrotic collections.
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PMID:Retroperitoneal laparostomy as an effective emergency treatment of abscess and multiple organ failure after blunt duodenal trauma: report of a case. 774 66

Retroperitoneal abscess is a rare condition which is difficult to diagnose and treat because of its insidious onset. Herein, we present a case of retroperitoneal abscess secondary to a perforation that occurred during an ERCP. A 54-year-old female patient was admitted to an outside hospital with gallstone pancreatitis and underwent ERCP with sphincterotomy followed by laparoscopic cholecystectomy. An abdominal CT scan was performed at the outside hospital 10 days later for worsening abdominal pain which showed multiple loculated pockets in the right upper and lower quadrant. Her condition improved after IV antibiotics and percutaneous drainage. Her symptoms recurred a month later and she presented to our hospital. Repeat abdominal CT scan at our hospital revealed recurrence of her abscesses. Multiple drains were placed and the abscess cavity was washed out without much improvement. EGD revealed a small mucosal defect in the distal portion of the duodenal bulb which was closed successfully using an over-the-scope clip. Repeat CT scan after 8 weeks from the endoscopic closure showed near complete resolution of the abscess. ERCP-associated perforation is a rare complication and can be challenging to diagnose and treat; prompt recognition is mandatory for favorable prognosis. Our patient was managed successfully via nonsurgical approach.
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PMID:A Case of Unresolved and Worsening Retroperitoneal Abscess. 2959 17