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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

22 out of 180 patients with chronic relapsing pancreatitis showed an acute hemorrhagic-necrotizing exacerbation. in 11 out of these there was an indication for operative management of the chronic pancreatitis before onset of the acute exacerbation. The clinical picture is similar to that of the acute hemorrhagic-necrotizing pancreatitis. The surgical procedure consisted in digital removal of necrotic tissue and left-sided resection. 13 out of the 22 patients survived.
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PMID:[Treatment of chronic recurrent necrotic pancreatitis]. 61 85

A case of retroperitoneal fibrosis causing pancreatitis is reported; another case is reported as well, where chronic pancreatitis caused secondary symptomatic retroperitoneal fibrosis. Differential diagnosis of the 2 diseases is discussed. Surgical therapy has to eliminate complications and reduce retroperitoneal fibrous tissue structures; this has to be followed by continuous drug therapy aimed at slowing proliferation of fibrous tissue.
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PMID:[Retroperitoneal fibrosis and pancreatitis (author's transl)]. 63 6

Thirty cases of pancreatitis in children are reviewed. Diagnosis is based on the clinical findings of pancreatic inflammation, laboratory confirmation with elevated serum and/or urinary amylase values, and in some cases surgical or postmortem tissue substantiation. Four major classes of pancreatitis are defined in children: (1) traumatic; (2) systemic-disease associated; (3) drug-induced, caused by drug therapy for various life-threatening diseases, and (4) chronic pancreatitis, with or without an anatomic abnormality. If cases of traumatic pancreatitis are excluded, females outnumber males 5 to 1. A high index of suspicion is necessary to make the diagnosis, and this is very important if the mortality for pancreatitis in children is to be lowered. Awareness and consistent early aggressive intervention should increase the salvage rate.
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PMID:Pancreatitis in childhood. 65 Mar 64

When studying the leucocytic index of intoxication (LII) in 94 pancreatitis cases the highest values of it were found in case of destructive forms of the disease. In patients with edematous and chronic pancreatitis LII values were smaller. No correlation between LII and urine diastase was found. LII permits to assess impartially the degree of intoxication in various forms of pancreatitis.
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PMID:[Changes of the leukocytic index of intoxication in pancreatitis]. 65 75

The application of two retrograde pancreato-cholangiographies is reported in patients with papillo-oditis and chronic pancreatitis. The advantages of the method for the diagnosis of the diseases of bile and pancreatic duct systems are stressed upon. Temporary and rapid transitory diastases elevation in serum and urine was observed without pancreatitis manifestations.
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PMID:[Endoscopic retrograde pancreatocholangiography (ERPC) (a preliminary report of 2 cases)]. 65 39

The clinical and pathological features of 132 patients of North-Eastern Italy with proven chronic pancreatitis (presence of radiological pancreatic calcification and/or surgical and histological data) have been studied. The disease appeared to be associated with chronic and regular alcoholic habits in most cases. Histo-pathological examinations showed calcifying pancreatitis also in patients without radiological pancreatic calcification. Chronic pancreatitis in North-Eastern Italy seems to be similar to that described in France, except for a high frequency of associated gallstones.
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PMID:Chronic pancreatitis in north-east Italy: a clinical and pathological study. 65 45

Endoscopic retrograde cholangiopancreatography (ERCP) is essential in the diagnosis of pancreatic disease, jaundice and in post-cholecystectomy syndromes, as well as in cases where cholecystography and i.v. cholangiography fail to explain disturbances that strongly suggest bile duct involvement. Its confirmation of clinically established pancreatic disease is much more positive than that given by scintiscanning and multiple superselective arteriography. Unlike the latter, it also permits the differential diagnosis of chronic pancreatitis, cancer of the pancreas, pseudocysts, etc. and distinguishes medical and surgical pancreatitis (stenosis, proteinaceous calculi, and obstructing pseudocysts). Differential diagnosis of progressive jaundice on clinical grounds or with the aid of ordinary means of examination is sometimes unsatisfactory. ERCP clearly distinguishes medical and surgical forms, so that exploratory laparotomy is not needed in subjects with liver-cell forms. It also shows the nature, site and extent of extrahepatic obstruction, and points to the organic cause in 79% of cases of postcholecystectomy syndrome. Right hypochondrial pain or intermittent jaundice and negative cholecystography and i.v. cholangiography is a further indication, since ERCP will reveal disease of the pancreas or bile ducts (cholelithiasis, choledocholithiasis, sclerosing cholangitis, etc). It is also useful in the diagnosis of cirrhosis, abscess, echinococcus cyst and primary or secondary cancer in cases where needle biopsy and-or arteriography are either contra-indicated or inconclusive.
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PMID:[Diagnostic value of retrograde cholangiopancreatography by transendoscopic route]. 66 74

A review of abdominal radiographs of 50 patients with the clinical diagnosis of chronic pancreatitis showed calcific pancreatitis in 27 patients. Ten patients had severe pain associated with weight loss. Five had obstruction of the duct of Wirsung: one by a pseudocyst and four by large stones near the ampulla of Vater. The radiologic workup presented emphasizes the need to study the duct of Wirsung in patients with chronic pancreatitis to guide the surgical approach for relief of intractavle pain. Theories regarding the pathophysiology of calcium deposition and stone formation and migration are reviewed.
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PMID:Calcifications within the duct of Wirsung in calcific pancreatitis. 66 83

An analysis of 89 cases with chronic pancreatitis revealed 56% of chronic alcoholic pancreatitis (AP). The sex ratio was 47 males to 3 females and the mean age at onset was 42.4 years in AP and 49.3 years in chronic non-alcoholic pancreatitis (NAP). The 'total amount' of alcohol consumption was correlated to the onset. In AP, the abdominal pain was apt to relapse and severe in nature, furthermore painless pancreatitis was seen in 6%. The association with diabetes or calcification (38%) were more frequently seen in AP. The calcifications in AP appeared to be smaller in size and distributed diffusely or localized in cephalic portion. A striking frequency of liver dysfunctions (39 cases) were demonstrated, however, cirrhosis was rare in AP. The P-S test dysunctions in NAP were frequently reversible in the follow up study, while even some of chronic asymptomatic alcoholics developed clinical signs of pancreatitis during the observed period and proceeded to definite AP, of whom pancreatic dysfunctions showed fluctuation and eventual progression. In other words, even pain free intervals the pancreatic inflammation in susceptible persons may proceed to ultimated destruction of the pancreas. The fatality from chronic pancreatitis was rare (12.3%), which was related diabetes mellitus.
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PMID:A clinical investigation of chronic pancreatitis--comparative study between alcoholic pancreatitis and non-alcoholic pancreatitis--. 66 97

Information from 72 patients from 7 families in England and Wales confirms that hereditary pancreatitis is inherited as an autosomal dominant conditions with limited penetrance. The degree of penetrance is approximately 80%. These patients have had recurrent attacks of abdominal pain starting from childhood or young adult life. The mean age of onset in the 7 families studied was 13.6 years. There were two peaks, with maximum numbers at 5 years and 17 years. The second peak was thought to represent genetically susceptible individuals having pain brought on by alcohol rather than representing evidence of genetic heterogeneity. Five of the 7 families had members with both childhood and adult ages of onset. Only 4 patients out of 72 had life-threatening disease and in the majority of cases the attacks of pain were of nuisance value only. Hereditary pancreatitis was implicated in only 1 patient's death and this was not definite. Patients appear to get better after a period of symptoms usually as they approach middle age, or after a severe attack. In older patients alcohol, emotional upsets, and fatty food appear to precipitate attacks. Pancreatic insufficiency (5.5%), diabetes mellitus (12.5%), pseudocysts (5.5%), and haemorrhagic pleural effusion are uncommon complications. Portal vein thrombosis occurred definitely in 2 patients and was suspected in 3 others. Carcinoma of the pancreas was not found in any of 72 patients studied in detail; however, 2 members from a family not visited personally had chronic pancreatitis and malabsorption going on to carcinoma. They may have suffered from a different disease. Genetic linkage information was too slight for many definite conclusions. However, there was no suggestion of linkage with any of the markers tested.
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PMID:Hereditary pancreatitis in England and Wales. 67 83


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