Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 45-year-old man presented with what was thought to be a mass in the left upper lung and a pericardial friction rub. He was subsequently discovered to have a loculated pleural effusion and pericardial effusion associated with chronic pancreatitis. This is the first instance we were able to find of pancreatitis mimicking bronchogenic carcinoma with pericardial metastasis.
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PMID:Pancreatic pleuropericardial effusions presenting as tumor of the lung. 59 5

After a short description of the physical principles of ultrasound, the indications and usefulness of the real time B-scan technique in the non-invasive diagnosis of cardiac and abdominal diseases are discussed. A correct diagnosis was made in 90% of the cardiac cases (valve abnormalities, pericardial effusion, cardiac aneurysm, cardiomyopathy), whereas the diagnosis by ultrasound was correct in only 81.1% of the abdominal cases (diffuse and localized liver diseases, pancreatitis, pancreatic cyst, carcinoma of the pancreas, cholelithiasis, renal cyst, renal tumours, aortic aneurysm). The advantages of the real time B-scan technique lie in the two-dimenstional clear representation of intracardiac and intraabdominal structures with the possibility of undertaking quantitative measurements. Furthermore, it is a non-invasive and safe method, which can be repeated as often as necessary and can complete the diagnositic spectrum of radiology, endoscopy and nuclear medicine.
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PMID:[Ultrasonic diagnosis of cardiac and abdominal diseases using real time b-scan technique (author's transl)]. 65 98

Ascites and pleural effusions may complicate pancreatitis but pericarditis with pericardial effusion and tamponade is rare and necrosis of mediastinal fat has not been described before. All these complications occurred in the case reported here.
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PMID:Rare intrathoracic complications in acute pancreatitis. 206 4

Pericardial effusion as a complication of acute pancreatitis has been described in several isolated case reports. However, the prevalence of pericardial effusion in patients with acute pancreatitis has not been studied. Alcoholism and severe acute pancreatitis have been shown to cause left ventricular dysfunction. We studied 15 consecutive patients, hospitalized for the treatment of acute, alcohol-induced pancreatitis, and 28 control subjects by M-mode echocardiography to detect pericardial effusion and to assess left ventricular function. Seven patients (47%) with pancreatitis and three control subjects (11%) had pericardial effusion; the prevalence of pericardial effusion in patients with pancreatitis was significantly greater (Fisher's exact test) than in control subjects. There was no evidence of impairment of left ventricular function in the patients, all of whom had mild acute pancreatitis; the mean fractional systolic shortening of the left ventricle in patients was not significantly different from that of control subjects (38% +/- 8.5% vs 37% +/- 8.0%), and the mean velocity of left ventricular circumferential shortening in patients was significantly higher than in control subjects (1.58 +/- 0.34 circumferences per second vs 1.29 +/- 0.32 circumferences per second). We conclude that in patients with mild acute alcohol-induced pancreatitis, pericardial effusion occurs frequently and that left ventricular function is unimpaired.
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PMID:Pericardial effusion and left ventricular function in patients with acute alcoholic pancreatitis. 357 45

Four patients had pancreatitis associated with valproic acid therapy. Three patients received valproic acid at usual doses, and all were free of other symptoms of toxic reactions, with serum levels of valproic acid in the usual therapeutic range. Two patients underwent exploratory laparotomy prior to diagnosis. Complications included pseudocyst, pericardial effusion, laparotomy wound infection, and coagulopathy. All patients recovered with discontinuation of valproic acid therapy and enteral feeding and administration of intravenous fluids. After recovery, a valproic acid regimen was restarted uneventfully (in one patient). All were asymptomatic with normal serum amylase levels after five to 14 months. Pancreatitis is a serious complication of valproic acid therapy that must be considered in any patient receiving valproic acid who experiences severe abdominal pain and vomiting.
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PMID:Pancreatitis associated with valproic acid therapy. 620 16

Ascites and pleural and pericardial effusions can be observed during acute pancreatitis. The aims of this study were to evaluate their incidence, natural history, and prognostic role in patients with acute pancreatitis. One hundred patients consecutively admitted with a diagnosis of acute pancreatitis were prospectively submitted to abdominal, pleural, and cardiac ultrasonography at admission and during follow-up. Ascites was found in 18 patients, pleural effusion in 20, and pericardial effusion in 17. Twenty-four patients of this series had severe pancreatitis; three of them died. All effusions disappeared spontaneously in patients who survived pancreatitis up to two months after dismissal. At multivariate analysis ascites and pleural effusion were demonstrated to be accurate independent predictors of severity. The respective odds ratios were 5.9 [95% confidence interval (CI), 1.5-23.0%) and 8.6 (95% CI, 2.3-32.5%). Furthermore the presence of pleural effusion, ascites, and pericardial effusion were associated with an increased incidence of pseudocyst during follow-up. Ascites and pleural and pericardial effusions are frequent during acute pancreatitis. Pleural effusion and ascites are accurate predictors of severity in these patients.
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PMID:Ascites, pleural, and pericardial effusions in acute pancreatitis. A prospective study of incidence, natural history, and prognostic role. 862 53

A 47-year-old woman with acute necrotizing pancreatitis developed sudden cardiorespiratory arrest and needed resuscitation. A pericardial effusion was found, and 350 ml of a white nontransparent milky fluid was aspirated that contained 1020 mg triglycerides/100 ml. The diagnosis of chylous cardiac tamponade was made. Absence of amylase in the chylous effusion militates against the popular hypothesis that lymphatic transport of exocrine digestive enzymes from the inflamed pancreas produces the frequent intrathoracic serosal effusions in acute pancreatitis. The data of our patient rather suggest that these effusions result from the leakage of pancreatic inflammatory exudates through the diaphragm which, apparently, may even result in the loss of pericardial and adjacent thoracic lymph vessel integrity. Although pericardial tamponade is a rare complication, it should be considered if otherwise unexplained circulatory deterioration occurs in a patient with acute pancreatitis.
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PMID:Chylous cardiac tamponade in acute pancreatitis. 888 9

We report a well-documented case of relapsing chronic calcifying pancreatitis with recurrent pleural and pericardial effusions during episodes of clinical and biochemical relapse of the pancreatitis. Pericardial effusions in association with pancreatitis have been reported only very occasionally, almost exclusively in chronic alcoholic pancreatitis with pseudocyst formation. Our successful conservative treatment consisted of parenteral nutrition and a continuous infusion of somatostatin for 6 weeks. We discuss other reported cases and proposed mechanisms of pathogenesis.
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PMID:Recurrent pericardial effusion as a result of chronic pancreatitis. Successful treatment with somatostatin. 889 8

Authors report a case of relapsing chronic calcifying pancreatitis with pleural and pericardial effusions during an episode of acute exacerbation. A large multilocular pancreatic pseudocyst expanded into the mediastinal space resulting in pericardial effusion that caused cardiac tamponade with severe circulatory deterioration. After resuscitation and pericardiocentesis a successful surgical procedure was performed, which produced rapid clinical improvement. Authors discuss this uncommon complication and review the proposed pathogenic mechanisms and possible therapeutic interventions.
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PMID:Cardiac tamponade as a complication of pseudocyst in chronic pancreatitis. 1199 98

Cardiac complications from a pancreatic mediastinal pseudocyst are rare. Pericardial effusions associated with pancreatitis have been reported only very occasionally. To the best of our knowledge, the direct extension of a pancreatic pseudocyst into the pericardial sac causing tamponade has not been described before. We present a case in which a pancreatic pseudocyst masquerading as a pericardial effusion dissected into the mediastinum, eroding into the pericardial sac and causing a life-threatening pericardial tamponade. A pericardial catheter was placed producing rapid symptomatic relief. Surgery was avoided by the use of octreotide as an adjuvant to ultrasound guided catheter drainage of the pseudocyst and it resolved completely within 4 weeks of admission to hospital. The importance of rapid and accurate diagnosis of this life-threatening complication is reiterated and the management of pancreatic mediastinal pseudocyst is discussed.
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PMID:Cardiac compromise due to a pancreatic mediastinal pseudocyst. 1243 27


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