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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We present a case of osteolytic lesions secondary to medullary fat necrosis associated with pancreatitis. The bone lesions are usually secondary to pancreatic trauma and evaluation of possible child abuse is indicated. The roentgenographic findings may not be seen until three to four weeks after the onset of pancreatic disease, and must be differentiated from osteomyelitis and traumatic periostitis. The presence of multiple lesions in many bones without substantial clinical signs of infection should suggest the pancreas as the primary problem.
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PMID:Osteolytic lesions following traumatic pancreatitis. 87 10

One hundred and ninety-three nephrotic children with a total of 271 admissions during the past decade, from 1980 to 1989, were retrospectively reviewed for acute complications and unusual features of nephrotic syndrome. One hundred and forty-nine patients were male, 44 female. Hypertension was found in 41 children (21.2%). Nine patients (4.7%) had a total of 11 episodes of hypovolemic shock. These shock patients had a more severe hemoconcentration (mean hemoglobin concentration 19.6 +/- 1.5 g/dl) and hyponatremia (mean serum sodium 127.5 +/- 8.5 mmole/L). Bacterial infections occurred in 28 children (14.5%) with primary peritonitis in 13, sepsis in 6, cellulitis in 4, urinary tract infection in 4 and osteomyelitis in 1. Almost all infections were caused by gram-negative bacilli. Other complications or features included tetany in 4 (2.1%), thromboembolism in 2 (1.0%), pancreatitis in one (0.5%) and Fanconi syndrome in one (0.5%).
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PMID:Complications of nephrotic syndrome in children. 168 Oct 1

Case reports of 4 patients with combined pancreatic and bone marrow disease are presented. 3 of them were alcoholics and suffered from chronic pancreatitis and bacterial osteomyelitis, one showed lipolytic lesions of the bone marrow following an acute exacerbation of a chronic lithogenic pancreatitis. X-ray examination of the left hand, both feet and tibiae showed evidence of multifocal small osteolytic defects accompanied by periosteal reaction in the case of lipolytic bone lesions. The appearance resembles that of an osteomyelitis, however, lacking the extensive destruction and sclerotic reaction. These bone lesions were associated with neurological symptoms and subcutaneous nodules. In one patient histological investigation of the bone lesions showed osteomyelitic and lipolytic changes so that there might be an association between both diseases.
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PMID:[Bone lesions in chronic pancreatitis]. 284 60

Vertebral osteomyelitis rarely mimics pancreatitis. However, the potential consequences of longstanding unrecognized disease, including neurological impairment and bony deformity, should make it an item in the differential diagnosis of chronic pancreatitis. In the evaluation of our patient, four items were of particular importance: awareness of his previously documented S. aureus bacteremia, a markedly elevated ESR, an abnormal chest radiograph, and the positive bone scan.
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PMID:Vertebral osteomyelitis mimicking chronic pancreatitis. 868 35

Intrarenal abscesses remain a significant cause of morbidity and mortality as well as a diagnostic dilemma because a plethora of microorganisms can cause this condition. A definitive diagnosis is made by demonstrating the organisms from the aspirate and the success or failure of therapy depends upon the antimicrobial sensitivity pattern. Enteric fever is a multisystem disorder caused by invasive strains of salmonella. Salmonellosis continues to be a major public health problem, especially in developing countries. Classic enteric fever is caused by S. typhi and usually less severe enteric fevers are caused by S. paratyphi A, B, or C. However, at times S. paratyphi is capable of causing serious and often life-threatening infections like infective endocarditis, pericarditis, empyma, sino-venous thrombosis, osteomyelitis, meningitis, bone marrow infiltration, hepatitis and pancreatitis. There are anecdotal case reports in world literature of abscesses being caused by this organism. Renal involvement like bacteriuria, nephrotic syndrome and acute renal failure have been reported due to S. parayphi A. S. paratyphi A has never been implicated in renal abscess, we report one such case that was managed successfully with medical therapy.
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PMID:Isolation of Salmonella paratyphi A from renal abscess. 1913 4

A 50-year-old man with a history of alcohol-induced pancreatitis was admitted to a hospital with swelling and pain of the right ankle, and fever, and was suspected to have osteomyelitis. Radiographs of the fingers, ankles, and feet, in which pain and swelling were present, revealed multiple pathological fractures. The histological examination of the tissue sample in the right radius showed sequestrated fat necrosis. Bacterial culture test remained negative. Based on the findings mentioned above, a diagnosis of intraosseous fat necrosis associated with pancreatitis was made. Treatments proven to be effective in the literature for pancreatitis were started. Symptoms of the bones and joints gradually improved. However, pancreatitis relapsed, triggered by drinking, 4 months after discharge. He had complaints of back pain without any history of trauma. Radiographs showed fractures of the entire vertebral body from the 12th thoracic to 5th lumbar vertebrae. What was interesting about the present case was that, after the pathological fractures of the extremities were completely resolved, osteonecrosis relapsed as pancreatitis deteriorated, resulting in pancreatic cyst rupture into the intrathoracic cavity and vertebrae, differing from the previous lesions that were affected. There are very few cases of pathological fracture induced by pancreatitis that affect the vertebrae.
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PMID:Pathological fracture due to vertebral osteonecrosis associated with pancreatitis. 2023 71

Campylobacter jejuni is a common cause of gastroenteritis especially in childhood. However, extraintestinal manifestations of C. jejuni such as bacteremia, cholecystitis, pancreatitis and osteomyelitis are rare. Meningitis in newborns caused by this organism is unusually rare. We report a case of neonatal meningitis in a 15-day old term boy caused by Campylobacter jejuni.
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PMID:Campylobacter jejuni meningitis in a neonate: a rare case report. 2424 22

Pancreatic diseases can be accompanied by periarthritis with bone necrosis and panniculitis (PPP-syndrome). It is postulated that this is caused by systemic activity of pancreatic enzymes leading to microcirculatory disturbances and fat necrosis. The morbidity and mortality of the PPP-syndrome is high. Successful treatment of pancreatitis can lead to resolution of accompanying panniculitis and periarthritis without adverse sequelae, but weeks or months after pancreatitis, asymptomatic necrosis of the bone may become symptomatic by fracturing spontaneously. In this report, we also describe osteomyelitis as a severe septic complication of bone necrosis caused by pancreatitis, in one case as acute tissue necrosis and in another case months after pancreatitis spread haematogenously.
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PMID:Osteomyelitis: A rare complication of pancreatitis and PPP-syndrome. 2647 14