Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty episodes of serious gastrointestinal complication occurred in 14 of 85 (16%) consecutive patients less than 17 years old who underwent renal homograft transplantation. These complications consisted of small-bowel obstruction, ulceration, pancreatitis, hepatitis, ascites, and severe gastroenteritis. Only 1 patient died as a consequence of the complication--a much lower mortality rate than that reported for gastrointestinal complications of renal transplantation in adults. Radiographic findings were diagnostic in the majority of cases and aided in the prompt administration of therapy.
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PMID:Gastrointestinal complications of renal transplantation in children. 36 63

Two cases of acute pancreatitis in pregnancy occurred among Vietnamese evacuees in Arkansas. In both cases, Ascaris lumbricoides seemed the likely cause. In endemic areas including the rural southeastern United States, a high index of suspicion for ascariasis is needed because these worms may cause a variety of abdominal disorders including pancreatitis, cholecystitis, and bowel obstruction. In appropriate settings, a therapeutic trial with antihelminthics is indicated.
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PMID:Acute pancreatitis in pregnancy with Ascaris infestation. 83 Nov 88

Forty-two cases of progressive systemic sclerosis were reviewed. A compression defect of the duodenum was found at the site where the superior mesenteric artery crossed the duodenum in all patients with duodenal dilatation. A similar observation was made in patients with small-intestinal obstruction and pancreatitis. Both the defect and dilatation may spontaneously disappear and return. The author concludes that in the cases studied, the compression produced by the superior mesenteric artery is secondary to dilatation and loss of muscle tone of the duodenum. It does not cause obstruction, and its presence per se does not warrant a diagnosis of "superior mesenteric artery syndrome."
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PMID:Duodenal compression defect and the "superior mesenteric artery syndrome" 1. 87 Sep 33

Low-frequency impulse currents (Bernar current) are suggested for treatment of paralytic intestinal obstruction. The method was used in 108 patients, in whom the cause of paresis was as follows: acute purulent peritonitis, pancreatitis, operations on the abdominal aorta and its branches. In 102 patients the stimulation proved to be effective, in 6 cases of progressive purulent peritonitis no effect was gained. In a number of patients the procedure had to be repeated during 2--3 days. Generally, diadynamic currents were employed in a complex with other measures: syphon enema, paranephral blockade, cholinergics, etc. A grave cardiac pathology and oncological diseases are considered as contraindications.
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PMID:[Use of low-frequency currents in the treatment of severe intestinal paralysis]. 108 58

Of 126 renal allograft recipients, 34 were found to have gastrointestinal and hepatic complications. In order of frequency, these included: mild liver dysfunction, severe hepatitis usually associated with cytomegalovirus infection, peptic ulceration complicated by bleeding, intestinal obstruction, and pancreatitis. These complications did not appear to influence the long-term survival or function of the renal allograft, but proved to be fatal when massive infection of cytomegalovirus affected the gastrointestinal tract and especially the liver. Gastrointestinal and pancreatic complications occurring in renal allograft recipients can be managed in the same manner as in patients who are not receiving immunosuppression. When surgical intervention is required, it should be performed promptly. The fact that these patients are receiving immunosuppressive therapy should not be a contraindication to early surgical intervention. When the presence of ulcerative lesions of the gastrointestinal mucosa, pancreatitis, or hepatitis is confirmed, the possibility of these lesions being caused by viral agents, especially cytomegalovirus, should be considered and attempts to confirm this diagnosis should be made. If cytomegalovirus infection is confirmed and the patient is experiencing rejection of the allograft, careful consideration should be given to immediate discontinuation of immunosuppressive therapy followed by removal of the renal allograft. In this way the relentless and fatal course of the cytomegalovirus infection seen in some of the patients reported in this study may be avoided.
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PMID:Gastrointestinal and hepatic complications affecting patients with renal allografts. 109 Nov 74

Fourty-nine patients (21 female, 28 male) with ulcerative colitis underwent formation of an J-ileal pouch and construction of a direct stapled pouch-anal anastomosis (IPAA) without rectal cuff. 16 patients had previously undergone surgical interventions. Overall after IPAA 7 patients (14%) experienced 11 major complications. Gastrointestinal complications included hemorrhage in 1 patient, pelvic sepsis and ileus in 3 patients, respectively. Pancreatitis and urinary infection occurred in 2 patients, sexual dysfunction in 3 patients. After closure of the ileostomy 3 patients developed late pouch-vaginal or pouch-vesical fistulas, leading to excision of the pouch. During the long-term follow-up small bowel obstruction developed in 3 patients, pouchitis in another 6 patients. After 3 months 84% of our patients were continent during daytime, 67% during nighttime. 24 months postoperatively these data concerning continence increased to 92% and 83%, respectively. We conclude that direct IPAA is a reliable procedure achieving its purpose in 96%.
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PMID:[Direct ileum pouch-anal anastomosis in ulcerative colitis. Technique and complications]. 131 74

In recent ten years, physicians and surgeons in Beijing Tong Ren Hospital cooperated well in the treatment of acute hemorrhagic necrotic pancreatitis. Twenty four cases were chosen to determine whether medical conservative or surgical operative treatment should be given. In the surgical operation group there were fourteen cases. Twelve cases survived and the remaining two died. In the medical conservative group only one of the ten cases died. The overall mortality of the twenty four cases of acute hemorrhagic pancreatitis was 12.5%. In our study, the indications for operation were as follows: (1) Presence of more than five positive diagnostic criteria. (2) Accompaniment of gall stone. (3) Inability to differentiate with other acute surgical abdominal emergencies such as intestinal obstruction.
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PMID:[The choice of treatment in acute hemorrhagic necrotic pancreatitis: medical or surgical?]. 136 95

From 1986 to 1990, 46 patients with blunt liver trauma were hospitalized and operated on in Kuang Tien General Hospital. Included were 33 males and 13 females with a mean age of 31 years (range: 2 to 62). The mean duration of the follow-up was 43 months. We classified the severity of liver injury with the liver injury scale which was published by the Organ Injury Scaling (O. I. S.) Committee of the American Association for the Surgery of Trauma (A. A. S. T.) in 1989. According to the operative findings, the liver injury of the 46 cases were classified as follows: grade I 4 cases, grade II 18 cases, grade III 16 cases, grade IV 2 cases, grade V 4 cases, and grade VI 2 cases. Among the patients, 4 cases were treated with drainage. Four cases underwent simple repair. Twenty-seven cases were treated with repair and drainage. Three cases underwent debridement and selective ligation of bleeding vessels. Four cases underwent partial resection of liver, and 3 cases required repair of the inferior vena cava. One case was packed with gauze for hemostasis. The mortality rate was 15.2%, and the morbidity rate 30.3%. The most frequent postoperative complications related to the hepatic injury in the patients who survived the initial operation were wound infection (8.7%), intra-abdominal abscesses (6.5%), pancreatitis (6.5%), pulmonary infection (4.3%), and small bowel obstruction (4.3%).
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PMID:[Surgical management of blunt liver trauma]. 143 43

An individual who has cystic fibrosis (CF) may suffer from gastrointestinal problems related to inadequately controlled intestinal absorption secondary to the pancreatic insufficiency. These include neonatal meconium ileus, distal intestinal obstruction syndrome (DIOS), constipation and acquired megacolon, rectal prolapse and rarely pancreatitis. If the intestinal malabsorption is well controlled with an effective pancreatic enzyme preparation, DIOS, constipation and rectal prolapse are infrequent. Persisting gastrointestinal symptoms should be investigated thoroughly to exclude other disorders not directly related to the cystic fibrosis; these include cows' milk intolerance, coeliac disease, giardiasis, Crohn's disease and intra-abdominal malignancy. Both appendicitis and intussusception may cause difficult diagnostic problems particularly in patients who may also have distal ileal obstruction syndrome.
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PMID:Cystic fibrosis: gastrointestinal complications. 145 4

From 1986 to 1990, 94 patients with blunt splenic trauma were hospitalized and operated on in the Kuang Tien General Hospital. Included were 74 males and 20 females with a mean age of 33 years (range: 5 to 78). The mean duration of the follow-up was 40 months. We classified the severity of the injury according to the splenic injury scale which was published in 1989 by the Organ Injury Scaling (O.I.S.) Committee of the American Association for the Surgery of Trauma (A.A.S.T.). Based on the operative findings, the splenic injuries of the 94 cases were classified as follows: grade I--4 cases, grade II--14 cases, grade III--24 cases, grade IV--41 cases, and grade V--11 cases. Twelve of the patients were treated with splenorrhaphy, and 82 cases underwent splenectomy. The mortality rate was 5.3%, and the morbidity rate, 12.8%. The most frequent postoperative complications in the patients who survived the initial operation were wound infections (4.2%), small bowel obstruction (3.2%), pulmonary infection (3.2%), intra-abdominal abscesses (1.1%), and pancreatitis (1.1%).
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PMID:[Surgical management of blunt splenic trauma]. 146 43


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