Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030305 (pancreatitis)
16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chronic idiopathic intestinal pseudo-obstruction is a syndrome with substantial morbidity and mortality associated both with the syndrome and with its therapy. Standard therapy has included prokinetic agents and intravenous nutritional support when oral feedings are inadequate to maintain nutriture. We report three children with chronic intestinal pseudo-obstruction who experienced one or more attacks of pancreatitis. Two patients developed pseudocysts. One patient died. All three patients underwent cholecystectomy; one had stones, one had acalculous cholecystitis, and one had a normal gallbladder. All patients received prokinetic agents and total parenteral nutrition as therapy for their pseudo-obstruction. Candidate mechanisms to explain the etiology for pancreatitis in chronic intestinal pseudo-obstruction include biliary dysmotility associated with pseudo-obstruction and excessive cholinergic stimulation due to therapy with prokinetic agents.
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PMID:Recurrent pancreatitis in three patients with chronic idiopathic intestinal pseudo-obstruction. 191 56

To evaluate the likelihood that patients can be discharged from the hospital the day after open cholecystectomy, a prospective study of 500 consecutive patients undergoing cholecystectomy was undertaken. The study group included patients with associated acute and gangrenous cholecystitis, biliary pancreatitis and choledocholithiasis as well as those with diabetes, hypertension and obesity. Approximately one-fourth of the total group were discharged within 24 hours and over one-half in 48 hours. There was a significant correlation between advancing age and increasing length of stay. Almost one-half of the patients less than 35 years of age without acute or complicated disease were discharged within 24 hours, more than 80 per cent within 48 hours, and the mean length of postoperative stay (MLS) for these patients was 1.9 days. The presence of choledocholithiasis and fever greater than 101 degrees F. increased MLS, while acute cholecystitis, hyperamylasemia and leukocytosis did not. Early discharge from the hospital after open cholecystectomy, even in sick patients, is safe and cost-effective.
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PMID:Twenty-four hour hospitalization after cholecystectomy. 194 86

This study reviewed the findings from ultrasound reports and medical notes of 303 patients examined by ultrasound between January 1985 and December 1987. It established the accuracy with which ultrasound could diagnose the cause of obstructive jaundice at 49.5%. A correlation was discovered between the actual pathology causing the obstruction and biliary dilatation and the degree to which the common duct became dilated. Further research into this area using a greater number of statistics is required before this can be applied in a clinical situation, but generalisations were formulated and could be used as guidelines to suggest, rather than state, the possible cause of the common duct obstruction. The following mean diameters for seven pathologies were established: duodenal (8.4 mm); cholecystitis (8.7mm); cholecystectomy (9.5mm); lymph nodes (9.5mm); pancreatitis (9.8mm); duct stones (11.0 mm); and pancreatic carcinoma (14 mm).
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PMID:Biliary dilatation--the accuracy of ultrasound in determining the cause. 200 74

Sonographic identification of thickening of the gallbladder wall that consists of multiple striations (alternate hypoechoic and hyperechoic layers) has been considered strong evidence of the presence of acute cholecystitis. We studied 27 patients in whom sonograms showed striated thickening of the gallbladder wall to determine the diagnostic significance of this finding. Striations were classified as focal or diffuse. Sonograms were correlated with pathologic findings in 16 patients and with clinical diagnoses and laboratory findings in 11. Patients were categorized as having cholecystitis with or without gangrene or edema of the gallbladder wall unrelated to gallbladder disease. Striated thickening of the gallbladder wall was due to cholecystitis in 10 patients, and all 10 had gangrenous changes at surgery or at pathologic examination. Striations were focal in eight of these patients and diffuse in two. Striated thickening of the gallbladder wall was due to edema of the wall unrelated to gallbladder disease in 17 patients. Causes included congestive heart failure (n = 4), renal failure (n = 5), liver disease (hepatic failure [n = 1], hepatitis [n = 6]), ascites (n = 2), hypoalbuminemia (n = 3), pancreatitis (n = 1), blockage of the lymphatic/venous drainage of the gallbladder (n = 2), and prominent Rokitansky-Aschoff sinuses (n = 1). More than one abnormality was present in five patients. Striations were focal in 11 of these patients and diffuse in six. The sonographic finding of striated gallbladder wall thickening is no more specific for cholecystitis than the observation of gallbladder wall thickening by itself, and it may occur in a variety of diseases. However, in the clinical setting of acute cholecystitis, the presence of striations suggests gangrenous changes in the gallbladder. The extent of the striations (focal or diffuse) is not useful in predicting the cause of the striated gallbladder wall thickening.
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PMID:Sonography of the gallbladder: significance of striated (layered) thickening of the gallbladder wall. 201 56

Extracorporeal shock wave lithotripsy (ESWL) has been reported to be a safe and relatively effective non-invasive treatment for radiolucent gallbladder calculi in selected patients. Ideally, the goal of successful treatment is the passage of all fragments from the gallbladder into the intestinal tract. Biliary colic has been reported in up to 35% of treated patients, although complications such as cholecystitis, cholangitis, common bile duct obstruction, and pancreatitis are surprisingly infrequent. Cholescintigraphy is the procedure of choice in patients with biliary colic and suspected acute cholecystitis. It has proven to be more sensitive than ultrasound in detecting acute common bile duct (CBD) obstruction, since functional obstruction precedes morphologic dilatation of the CBD. This report reviews two cases of post-lithotripsy cystic and common duct obstruction and discusses the role of Tc-DISIDA scintigraphy following gallstone ESWL.
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PMID:Biliary complications of gallstone lithotripsy detected by Tc-99m DISIDA scintigraphy. 203 26

With the introduction of ultrasonic examination (USE) and computed tomography into practice, nonparasitic cysts of the liver are recognised much more frequently. They were revealed by USE in 0.99% and by computed tomography in 2.3% of cases. The author analyses 90 patients with hepatic cysts, 13 of them had oncological diseases, 15 had cholecystitis and pancreatitis, and 26 had ischemic heart disease and hypertension. A complicated course and rapid growth of the structures were the indications for operation. Percutaneous puncture was conducted in 5 cases, 3 patients were operated on for cysts of the liver, in 5 patients the operation on the cysts was performed during cholecystectomy. The most expedient palliative intervention is excision of the external wall of the cyst and tamponade of the remaining cavity by a part of the greater omentum on a pedicle.
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PMID:[Diagnosis and treatment of non-parasitic cysts of the liver]. 204 21

Intraoperative cholangio-manometry with a miniature tensor sensor and graphic recording of the results were conducted to study the function of the major duodenal papilla in 53 patients. A periodical activity of the ampulla of the papilla was revealed, which was characterized by certain values of the peak and basal pressure, and duration of contraction and relaxation periods. The numerical values and the pattern of the pressure curve differed in patients with obstructive cholecystitis, biliary pancreatitis, and a concrement incarcerated in the ampulla of the papilla. The informativeness of the study increases with the use of the glucagon test.
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PMID:[Prospects of intraoperative dynamic cholangio-manometry by tensor detectors with graphic recording of pressure function]. 204 46

The author describes the results of examining 120 patients with chronic recurrent pancreatitis, 110 patients with chronic non-calculous cholecystitis and 70 patients with duodenal ulcer to detect the abdominocardial syndrome (ACS). Shows the rate and the most characteristics complaints of patients with the indicated syndrome, gives the detailed characterization of the main clinical manifestations of the ACS. Provides the data on microcirculation and ECG studies at the polyclinical stage and results of studying myocardial contractility, peripheral hemodynamics and immunological parameters under inpatient conditions. Notes the greatest degree of changes among patients with chronic pancreatitis and cholecystitis associated with the ACS.
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PMID:[The abdominocardial syndrome. Detection and treatment before hospitalization]. 205 8

Experiments on dogs demonstrated the role of chronic disorders of duodenal patency (ChDDP) in the development of immediate and late-term postoperative complications of gastric and duodenal ulcer, like incompetence of the duodenal stump, reflux gastritis, progression of duodenostasis existing before the operation, the afferent loop syndrome, postresection cholecystitis and pancreatitis, the dumping syndrome. The formation of valvar anastomoses and early recognition and correction fo ChDDP in resection of the stomach (554 patients) made it possible to reduce significantly both the mortality rates (0.18%) and the percentage of other complications.
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PMID:[Correction of chronic disorders of duodenal patency in the prevention of postoperative complications of peptic ulcer]. 207 14

Of 570 ERHP performed in patients with biliary tract and pancreas diseases, duodenal diverticuli were found in 67 (11.8 per cent). Diverticuli were more frequently diagnosed in patients beyond 60 years of age (67.2 per cent). In 83.6 per cent the diverticuli were single, mostly measuring 15-30 mm and localized in the peripapillary area (70 per cent). ERHP was successful in 85 per cent. Diverticuli were most frequently accompanied by stenosing papillo-odditis (82 per cent), cholecystitis (67 per cent), common bile duct calculosis (58 per cent), followed by pancreatitis (37 per cent) and cancer of the bile ducts (4.5 per cent). Endoscopic treatment was conducted in 46 cases: endoscopic sphincterotomy, hydrostatic balloon dilation of narrowed segments, hydrostatic balloon extraction of calculi, mechanical lithotripsy, nasolabial drainage and endoprosthesis. Significantly lower was the technical success of endoscopic sphincterotomy (78 per cent) when compared with its performance in patients without diverticuli (99 per cent). In spite of this, complex endoscopic treatment resulted in significant fall of bilirubin level (t = 6.58; p less than 0.0001), of AP (t = 8.15; p less than 0.001), of GGJP (t = 6.99; p less than 0.0001), of AcAT (t = 7.14; p less than 0.01). The incidence of complications (6.5 per cent) was not higher than the one observed in patients without diverticuli. In conclusion, endoscopic treatment of bile duct diseases is recommended to be performed also in patients with diverticuli, especially in adult patients and in those exposed to increased operative risk.
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PMID:[The relationship between duodenal diverticula, biliary tract and pancreatic diseases and their endoscopic treatment]. 212 48


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