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Query: UMLS:C0030305 (pancreatitis)
 16,014 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We present a case of osteolytic lesions secondary to medullary fat necrosis associated with pancreatitis. The bone lesions are usually secondary to pancreatic trauma and evaluation of possible child abuse is indicated. The roentgenographic findings may not be seen until three to four weeks after the onset of pancreatic disease, and must be differentiated from osteomyelitis and traumatic periostitis. The presence of multiple lesions in many bones without substantial clinical signs of infection should suggest the pancreas as the primary problem.
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PMID:Osteolytic lesions following traumatic pancreatitis. 87 10

Two cases of pancreatitis associated with the trauma of child abuse are reported. In the first case the skeletal survey was initially negative but the child later showed widespread roentgen evidence of intramedullary necrosis and periosteal new bone reaction. These lesions healed without treatment. In the second patient, the pancreatitis was accompanied by ascites and subsequently by bile peritonitis, duodenal obstruction, and a bile-filled abscess in the pancreas. This patient had skeletal fractures. The clinical problems of these 2 patients emphasize the need not only to relate pancreatitis to the battered child syndrome but also to distinguish between the bone changes due to direct trauma and those related to pancreatitis.
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PMID:Pancreatitis and the battered child syndrome. Report of 2 cases with skeletal involvement. 120 Feb 46

Pancreatitis in children is not common but can be associated with severe morbidity rates. We have treated 49 children with pancreatitis over the past 12 years ranging in age from 1 month to 18 years. One third of the patients had biliary tract disease as an etiology, with nearly half of these being related to underlying hematologic disease, usually sickle cell anemia. Another third of the pancreatitis was due to trauma, and one third of these were related to child abuse. Other etiologies were systemic disease (6 patients), congenital anomalies (8 patients), and idiopathic (3 cases). Eighty-two per cent of the patients presented with abdominal pain, but four children, all less than 4 years old, presented with an abdominal mass. Twenty-nine patients required 33 operations for pancreatitis. Fifteen of the 16 patients with biliary tract disease and all patients with congenital anomalies required operation. Six of the 16 patients with trauma required operation and none of those with systemic disease. As in adults ultrasonographic examination and CT scan are most important in the diagnosis; medical treatment consists of intravenous (I.V.) fluids, nasogastric suction, and total parenteral nutrition (TPN), and risk factors can help predict the severity of the disease while amylase alone is not related to severity. Different from adults, in children an etiology can usually be determined. The common etiologies, biliary tract disease, trauma, and congenital anomalies frequently require operation.
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PMID:Pancreatitis in childhood. Experience with 49 patients. 334 13

In a nine year old girl pancreatitis was suspected after roentgenologic demonstration of osteolytic lesions in the short bones of her hands and feet. Similar to the 18 cases found in the literature she had upper abdominal trauma in her history, and as in 6 other cases there was a history of child abuse and battering. There was complete remission of the lesions following operation of the pancreatic pseudocyst. In this disease pseudocysts develop very often, they were found in 12 of the 18 cases reported. There is no valid explanation of the pathogenetic mechanism leading to osteolytic lesions. Intracapillary coagulation might contribute to the development of necrotic areas in the bone. It is concluded that especially in patients with only slight upper abdominal pain roentgenologic examination of part of the skeleton might be helpful in establishing the diagnosis.
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PMID:[Traumatic pancreatitis with peripheral osteolysis suggesting child abuse]. 401 Jun 75

Blunt trauma to the abdomen is the main cause of pancreatic injury in childhood. One of the most common causes of injury is child abuse. Pancreatitis, pancreatic pseudocyst, and loculated peripancreatic effusion are sequellae of this trauma. The diagnosis of these lesions is aided by ultrasound. Pancreatic injury in children may require different methods of management than it does in adults. Persistently elevated serum amylase levels and increasing cyst size are indications for surgical intervention. However, the natural history of a pseudocyst in an otherwise normal child may lead to spontaneous resolution. In this report, three cases of pancreatic pseudocyst caused by child abuse are presented. In two of the patients, the cysts underwent spontaneous resolution.
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PMID:Sonography in the diagnosis and management of pancreatic pseudocysts and effusions in childhood. 615 10

A case of pancreatitis associated with trauma of child abuse is reported. Skeletal changes secondary to pancreatitis developed and the distribution of the bony lesions included both metaphyseal and epiphyseal growth centers. The coexistence of pancreatitis, child abuse, and subsequent skeletal lesions is again emphasized, as well as the unique occurrence of lesions in the epiphyseal centers.
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PMID:Pancreatitis, child abuse, and skeletal lesions. 722 Jan 34

The purpose of this manuscript is to provide an overview of the normal development of the pancreas as well as pancreatic pathology in children. Diagnostic imaging plays a major role in the evaluation of the pancreas in infants and children. Familiarity with the range of normal appearance and the diseases that commonly affect this gland is important for the accurate and timely diagnosis of pancreatic disorders in the pediatric population. Normal embryology is discussed, as are the most common congenital anomalies that occur as a result of aberrant development during embryology. These include pancreas divisum, annular pancreas, agenesis of the dorsal pancreatic anlagen and ectopic pancreatic tissue. Syndromes that can manifest pancreatic pathology include: Beckwith Wiedemann syndrome, von Hippel-Lindau disease and autosomal dominant polycystic kidney disease. Children and adults with cystic fibrosis and Shwachman-Diamond syndrome frequently present with pancreatic insufficiency. Trauma is the most common cause of pancreatitis in children. In younger children, unexplained pancreatic injury must always alert the radiologist to potential child abuse. Pancreatic pseudocysts are a complication of trauma, but can also be seen in the setting of acute or chronic pancreatitis from other causes. Primary pancreatic neoplasms are rare in children and are divided into exocrine tumors such as pancreatoblastoma and adenocarcinoma and into endocrine or islet cell tumors. Islet cell tumors are classified as functioning (insulinoma, gastrinoma, VIPoma and glucagonoma) and nonfunctioning tumors. Solid-cystic papillary tumor is probably the most common pancreatic tumor in Asian children. Although quite rare, secondary tumors of the pancreas can be associated with certain primary malignancies.
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PMID:Disorders of the pediatric pancreas: imaging features. 1553 62