Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0030193 (
pain
)
261,466
document(s) hit in 31,850,051 MEDLINE articles (0.10 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
16176
MRI
3345
She
3284
Mol
3255
opioid receptor
1966
substance P
1787
cytokine
1409
calcitonin
1366
TNF
1190
TRPV1
981
collagen
926
axonal
924
GABA
919
tumor necrosis factor
907
IL-6
874
COX-2
849
Hip
823
insulin
798
NMDA receptor
785
ATP
783
gut
780
bradykinin
767
beta-endorphin
740
cyclooxygenase
734
C-reactive protein
719
Pol
704
hemoglobin
696
reserved
670
nerve growth factor
656
ASA
594
ankylosing spondylitis
578
cyclooxygenase-2
555
CO2
524
alkaline phosphatase
519
ANOVA
518
transient receptor potential vanilloid 1
506
sodium channel
500
calcium channel
463
lipopolysaccharide
457
cage
457
brain-derived neurotrophic factor
448
DRG
443
P2X
431
Mot
424
p38
422
TRPA1
415
glial fibrillary acidic protein
413
CSF
413
Gen
409
interleukin-6
404
CB1
374
fused
360
COX-1
358
IL-10
353
nitric oxide synthase
352
cannabinoid receptor
339
5-hydroxytryptamine
333
CB2
329
cholecystokinin
326
short form
325
chemokine
324
creatine kinase
323
dynorphin
320
Mal
317
oxytocin
316
somatostatin
314
c-fos
304
osteosarcoma
291
CGRP
286
inducible nitric oxide synthase
282
CRP
275
ERK
274
PCA
268
ESR
268
P2X3
260
T12
259
MAPK
258
OFQ
257
IL-1
254
T10
248
more...
Disease
chronic pain
14578
cancer
13058
depression
9782
tumor
7664
osteoarthritis
7193
arthritis
4530
cold
4267
migraine
4149
rheumatoid arthritis
3888
diabetes
3351
fibromyalgia
2963
metastases
2896
neuropathy
2682
pruritus
2566
ischemia
2131
hypertension
2106
carcinoma
1844
arthrodesis
1782
stroke
1757
breast cancer
1757
addiction
1589
osteoporosis
1558
Frey
1508
arthropathy
1493
peripheral neuropathy
1449
trigeminal neuralgia
1395
endometriosis
1354
obesity
1229
irritable bowel syndrome
1227
HIV
1191
epilepsy
1156
myocardial infarction
1149
multiple sclerosis
1143
bone metastases
1125
hernia
1122
sickle cell disease
1063
postherpetic neuralgia
1049
chronic pancreatitis
1016
prostate cancer
1010
dysphagia
991
sepsis
964
diabetic neuropathy
961
anemia
921
Parkinson's disease
890
synovitis
881
sepsis
870
AIDS
866
herpes zoster
856
osteomyelitis
851
claudication
851
radiculopathy
845
pancreatitis
839
regional pain syndrome
816
psychological distress
802
uterus
800
dysplasia
799
cognitive impairment
791
rash
785
adenocarcinoma
773
dementia
767
carpal tunnel syndrome
699
myelopathy
670
tuberculosis
670
lung cancer
669
ankylosing spondylitis
666
acute myocardial infarction
660
infertility
654
Best
654
chronic disease
648
infectious diseases
646
incontinence
646
Alzheimer's disease
642
scoliosis
637
myocardial ischemia
634
gangrene
634
sleep disturbances
633
confusion
631
deep vein thrombosis
630
suicide
624
asthma
615
more...
Symptom
pain
261466
analgesia
14242
anesthesia
10421
headache
10057
discomfort
5569
discomfort
5315
fatigue
4991
low back pain
4304
nausea
3806
back pain
3796
weakness
3572
vomiting
3117
abdominal pain
3033
acute pain
2978
cancer pain
2630
numbness
1862
paresthesia
1686
diarrhea
1642
dyspnea
1598
nausea and vomiting
1553
constipation
1520
arthralgia
1477
neck pain
1472
chest pain
1461
myalgia
1409
erythema
1395
Neuropathic pain
1349
angina
1247
pelvic pain
1244
cough
1197
shoulder pain
1148
seizures
1092
knee pain
1086
facial pain
1014
neuralgia
919
sleepiness
914
spasticity
912
dizziness
900
Postoperative pain
862
insomnia
813
bone pain
809
distraction
801
leg pain
794
anorexia
793
collapse
792
spasm
782
functional recovery
680
agitation
676
orofacial pain
668
sciatica
621
dental pain
597
hip pain
575
tingling
511
dystonia
498
tremor
488
paresis
463
chronic back pain
440
Ill
422
photophobia
409
dysesthesia
384
dysuria
372
ataxia
361
breakthrough pain
355
colic
353
limb pain
338
tinnitus
325
bloating
312
vertigo
295
hypothermia
290
wrist pain
288
overweight
287
chills
284
groin pain
280
epigastric pain
273
shortness of breath
272
sore throat
260
Sedation
253
syncope
240
asthenia
239
heartburn
234
more...
Drug
Dermatol
1498
Cardiovasc
901
CSF
454
Gabapentin
358
Fentanyl
344
caffeine
334
nitroglycerin
317
Monit
255
Pregabalin
245
Bupivacaine
228
ENT
197
lysine
187
Propofol
173
Ketorolac
157
Indomethacin
155
Clonidine
144
MAP
137
Posture
137
Spectrum
137
Domperidone
130
Duloxetine
121
ascorbate
112
CTX
112
Nephron
104
Ranitidine
100
vitamin E
92
Leaf
91
BoNT/A
90
Dial
90
Histamine
89
9-THC
86
Oxaliplatin
86
IL-2
85
Codeine
83
Diclofenac sodium
83
Asthma
81
ampicillin
80
Xylocaine
80
Tapentadol
79
Codeine
78
THA
74
lactose
73
ICI
70
ROC
68
EE2
66
Norplant
65
Botox
64
Zoledronic acid
64
Voltaren
63
EHDP
62
SNL
62
CAM
61
Check
60
PTH
59
p75
58
ROS
57
Denosumab
56
FLP
56
Acyclovir
54
Ziconotide
54
Ketorolac tromethamine
53
Zoledronic acid
53
Gel
51
Portal
51
Xylocaine
51
Butorphanol
49
Xylocaine
48
IFN-gamma
47
G-CSF
46
Ethanol
46
CTX
45
CFS
44
CTX
44
Nimesulide
44
Prednisolone
43
Norplant
42
Triad
42
IL-1ra
41
Prednisone
41
Misoprostol
40
more...
Enzyme
mitogen-activated protein kinase
923
ERK
701
protein kinase
609
alkaline phosphatase
519
protein kinase C
515
creatine kinase
437
peroxidase
339
ACS
232
superoxide dismutase
223
catalase
208
focal adhesion kinase
204
alanine aminotransferase
190
aspartate aminotransferase
183
lactate dehydrogenase
183
botulinum neurotoxin
153
NO synthase
143
prostate-specific antigen
138
phospholipase C
134
tyrosine hydroxylase
131
trypsin
130
luciferase
127
collagenase
127
phosphodiesterase
121
lipase
114
thrombin
114
acetylcholinesterase
113
hyaluronidase
111
MEK
108
phospholipase A2
107
hyaluronidase
106
ACE
103
reverse transcriptase
102
ATPase
97
tissue plasminogen activator
95
MDP
94
CD10
92
caspase-3
92
calcineurin
90
guanylate cyclase
90
proteasome
88
lipoxygenase
87
alpha-galactosidase
83
renin
82
NOS
82
adenylate cyclase
74
kallikrein
73
monoacylglycerol lipase
73
thromboplastin
72
monoamine oxidase
72
glutathione peroxidase
70
urokinase-type plasminogen activator
68
CPT
67
cholinesterase
66
CYP3A4
64
prostaglandin synthetase
64
soluble epoxide hydrolase
63
CPT
62
CPT
62
MCS
60
APC
59
CaMKII
56
MAP
55
AST
55
acid phosphatase
52
CAD
51
CAD
51
CAD
51
P-glycoprotein
50
SCS
49
AMPK
47
caspase-1
47
tryptase
45
heme oxygenase
45
AMP-activated protein kinase
45
NADPH oxidase
44
NADPH oxidase
43
MIP
43
phosphatidylinositol 3-kinase
42
aldose reductase
42
PKG
40
more...
Compound
Clin
19856
Dec
17578
calcium
3373
water
2910
sodium
2737
oxygen
2525
glutamate
1578
glucose
1204
TNF
1190
Morphine
1173
nitric oxide
1127
acetic acid
1089
His
1084
5-HT
947
GABA
940
GABA
927
potassium
889
CO2
888
ASA
861
DNA
826
Cardiol
815
phosphate
802
ATP
790
ethanol
773
sulfate
747
NMDA
664
APAP
643
noradrenaline
639
acetate
608
creatinine
567
arginine
553
hyaluronic acid
465
titanium
442
tyrosine
409
Capsaicin
405
vitamin D
403
Lidocaine
386
Naloxone
372
tryptophan
360
PGE2
353
caffeine
346
copper
329
salt
326
Tramadol
322
iron
314
PGE
314
nitrogen
314
barium
313
hydrogen
312
Substance P
312
Phe
302
cAMP
296
gamma-aminobutyric acid
290
Ketamine
289
formaldehyde
283
lysine
282
Optimal
279
DSM
266
urea
264
silver
263
AMPA
249
Gly
249
T10
248
methionine
240
phenol
235
ACS
234
ACS
232
glycerol
229
Buprenorphine
222
iodine
222
N2O
221
HCl
221
Ibuprofen
219
Bupivacaine
219
zinc
218
galactose
217
Neuronal
212
cysteine
211
serine
210
Calcitonin
205
more...