Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030193 (pain)
261,466 document(s) hit in 31,850,051 MEDLINE articles (0.10 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 16176
MRI 3345
She 3284
Mol 3255
opioid receptor 1966
substance P 1787
cytokine 1409
calcitonin 1366
TNF 1190
TRPV1 981
collagen 926
axonal 924
GABA 919
tumor necrosis factor 907
IL-6 874
COX-2 849
Hip 823
insulin 798
NMDA receptor 785
ATP 783
gut 780
bradykinin 767
beta-endorphin 740
cyclooxygenase 734
C-reactive protein 719
Pol 704
hemoglobin 696
reserved 670
nerve growth factor 656
ASA 594
ankylosing spondylitis 578
cyclooxygenase-2 555
CO2 524
alkaline phosphatase 519
ANOVA 518
transient receptor potential vanilloid 1 506
sodium channel 500
calcium channel 463
cage 457
lipopolysaccharide 457
more...
Disease
chronic pain 14578
cancer 13058
depression 9782
tumor 7664
osteoarthritis 7193
arthritis 4530
cold 4267
migraine 4149
rheumatoid arthritis 3888
diabetes 3351
fibromyalgia 2963
metastases 2896
neuropathy 2682
pruritus 2566
ischemia 2131
hypertension 2106
carcinoma 1844
arthrodesis 1782
stroke 1757
breast cancer 1757
addiction 1589
osteoporosis 1558
Frey 1508
arthropathy 1493
peripheral neuropathy 1449
trigeminal neuralgia 1395
endometriosis 1354
obesity 1229
irritable bowel syndrome 1227
HIV 1191
epilepsy 1156
myocardial infarction 1149
multiple sclerosis 1143
bone metastases 1125
hernia 1122
sickle cell disease 1063
postherpetic neuralgia 1049
chronic pancreatitis 1016
prostate cancer 1010
dysphagia 991
more...
Symptom
pain 261466
analgesia 14242
anesthesia 10421
headache 10057
discomfort 5569
discomfort 5315
fatigue 4991
low back pain 4304
nausea 3806
back pain 3796
weakness 3572
vomiting 3117
abdominal pain 3033
acute pain 2978
cancer pain 2630
numbness 1862
paresthesia 1686
diarrhea 1642
dyspnea 1598
nausea and vomiting 1553
constipation 1520
arthralgia 1477
neck pain 1472
chest pain 1461
myalgia 1409
erythema 1395
Neuropathic pain 1349
angina 1247
pelvic pain 1244
cough 1197
shoulder pain 1148
seizures 1092
knee pain 1086
facial pain 1014
neuralgia 919
sleepiness 914
spasticity 912
dizziness 900
Postoperative pain 862
insomnia 813
more...
Drug
Dermatol 1498
Cardiovasc 901
CSF 454
Gabapentin 358
Fentanyl 344
caffeine 334
nitroglycerin 317
Monit 255
Pregabalin 245
Bupivacaine 228
ENT 197
lysine 187
Propofol 173
Ketorolac 157
Indomethacin 155
Clonidine 144
Spectrum 137
MAP 137
Posture 137
Domperidone 130
Duloxetine 121
ascorbate 112
CTX 112
Nephron 104
Ranitidine 100
vitamin E 92
Leaf 91
BoNT/A 90
Dial 90
Histamine 89
Oxaliplatin 86
9-THC 86
IL-2 85
Codeine 83
Diclofenac sodium 83
Asthma 81
ampicillin 80
Xylocaine 80
Tapentadol 79
Codeine 78
more...
Enzyme
mitogen-activated protein kinase 923
ERK 701
protein kinase 609
alkaline phosphatase 519
protein kinase C 515
creatine kinase 437
peroxidase 339
ACS 232
superoxide dismutase 223
catalase 208
focal adhesion kinase 204
alanine aminotransferase 190
lactate dehydrogenase 183
aspartate aminotransferase 183
botulinum neurotoxin 153
NO synthase 143
prostate-specific antigen 138
phospholipase C 134
tyrosine hydroxylase 131
trypsin 130
collagenase 127
luciferase 127
phosphodiesterase 121
lipase 114
thrombin 114
acetylcholinesterase 113
hyaluronidase 111
MEK 108
phospholipase A2 107
hyaluronidase 106
ACE 103
reverse transcriptase 102
ATPase 97
tissue plasminogen activator 95
MDP 94
CD10 92
caspase-3 92
calcineurin 90
guanylate cyclase 90
proteasome 88
more...
Compound
Clin 19856
Dec 17578
calcium 3373
water 2910
sodium 2737
oxygen 2525
glutamate 1578
glucose 1204
TNF 1190
Morphine 1173
nitric oxide 1127
acetic acid 1089
His 1084
5-HT 947
GABA 940
GABA 927
potassium 889
CO2 888
ASA 861
DNA 826
Cardiol 815
phosphate 802
ATP 790
ethanol 773
sulfate 747
NMDA 664
APAP 643
noradrenaline 639
acetate 608
creatinine 567
arginine 553
hyaluronic acid 465
titanium 442
tyrosine 409
Capsaicin 405
vitamin D 403
Lidocaine 386
Naloxone 372
tryptophan 360
PGE2 353
more...