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Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among the most important coronary risk factors are a diet rich in saturated fatty acids, cholesterol and calories, hypercholesterolemia, high blood pressure and excessive smoking. The typical pain can be elicited by putting a strain on the patient, e.g. climbing stairs. The disappearance of the pain after treatment with nitroglycerine is one of the most important pointers. Treatment is with nitroglycerine which, moreover, remains the drug of choice, also with nitrates such as pentaerythritol tetranitrate and with betablockers like propranolol. Favorable results have also been reported with a combination of isosorbide dinitrate and propranolol.
MMW Munch Med Wochenschr 1976 Sep 17
PMID:[Angina pectoris. Results of investigations to date (author's transl)]. 0 84

Volume-pulse digital plethysmography performed under ideal conditions on relatively fit adults has shown that lorazepam 4 mg intravenously abolishes the vasoconstriction of fear and restores the digital vasodilatation of the tranquil mind. The sedative effect of the drug is prolonged and is associated with several hours of anterograde amnesia from the time of its administration. The drug has no effect on the vasoconstrictor reaction to cold, pain, noise or other forms of adrenergic stimuli. Lorazepam seems to modify or prevent the psychomotor reactions which may complicate ketamine anaesthesia.
Anaesthesia 1976 Sep
PMID:The effect of lorazepam on the vasoconstriction of fear. 0 38

A single-blind non-crossover method for assessing the potential effectiveness of antirheumatic drugs has been described. The method employs entirely subjective indices and incorporates a daily pain chart for measuring the pain response over the duration of the trial. In addition, the mean number of days withdrawn and patients' satisfaction rating are measured. The statistical method can correct for initial imbalances between groups and allows for the valid comparison of drugs from separate trials. Ten antirheumatic medications were evaluated using this technique in 684 patients with rheumatoid arthritis, and the results are in agreement with those of previous studies using standard clinical methods. The new method is simple, rapid in performance, economical in terms of cost and time, and has been shown to be sensitive and reproducible. The results indicate that there are no significant differences in efficacy between the currently available non-steroidal, anti-inflammatory analgesic drugs, in the treatment of rheumatoid arthritis.
J Rheumatol 1976 Sep
PMID:Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis. 1 Apr 39

A comprehensive treatment program for chronic disability related to back disease has been presented. This program has used not only more traditional methods of medical care for the structural disabilities of chronic mechanical back disorders, but has used principles of active patient participation in the improvement process. The patients are educated in the manifestations of pain behavior in the phase II treatment program emphasis on pain sources is downgraded to allow positive reinforcement for healthy behavior to develop. By use of an organized team approach, a significant number of patients can be processed; and an overall reduction in use of alternative medical resources has occurred.
Pain 1976 Sep
PMID:A comprehensive treatment approach to chronic low back pain. 1 90

Eighteen patients with irritable colon syndrome were treated with a new anticholinergic drug (prifinium bromide) and with a placebo in a 6-wk, randomized, double-blind cross-over study. The drug was orally administered in a daily dose of 90 mg before meals. Three manifestations (pain, flatulence, constipation, and/or diarrhea), scored weekly, were used as assessment criteria. Mean over-all ratings showed a difference in favor of the drug, and were statistically significant. Side effects were rare and mild. We have come to the conclusion that this anticholinergic drug may be of benefit to patients with pain-predominant forms of irritable colon syndrome.
Gastroenterology 1979 Sep
PMID:Prifinium bromide in the treatment of the irritable colon syndrome. 3 42

Fourteen women with primary dysmenorrhea were administered four sessions of systematic desensitization (SD) by either a male or a female therapist. The following measures were taken during the flow periods before and after treatment and at a 6-month follow-up: menstrual symptom checklist, medication usage, invalid hours, and menstrual attitudes. At pretreatment, menstrually distressed women had significantly higher scores on all measures compared to a normative group and an explicitly nondistressed group. At posttreatment, treated women's scores on the dependent variables were significantly reduced. All indices were reduced to a "nondistressed level" at posttreatment and at 6-month follow-up. Type of dysmenorrhea (congestive vs. spasmodic), trait anxiety level, and therepist sex did not predict differential responsiveness to SD. SD did not affect frontailis EMG, peripheral blood flow, or pain threshold. A Retrospective Symptom Scale of menstrual distress was found to be highly reliable, valid, and sensitive.
J Behav Med 1978 Sep
PMID:Behavioral treatment parameters with primary dysmenorrhea. 4 34

The authors studied normal human skin reactions to two different rapid radiotherapy schedules of 2 sessions per day and evaluated their effectiveness in relief of pain and local tumor control. Patients were randomized to three treatment groups: SCHEDULE A (control): conventional one treatment per day regimen totalling 3,760 rads in 22-23 days; SCHEDULE B: 2 sessions per day totalling 3,440 rads in 10-11 days; and SCHEDULE C: 2 sessions per day totalling 3,568 rads in 10-11 days. The pattern and magnitude of skin reactions in the three schedules are nearly identical but tumor regression and pain relief were achieved faster in the rapid fractionation schedules.
Radiology 1975 Sep
PMID:Evaluation of rapid radiation treatment schedules utilizing two treatment sessions per day. 5 Jun 11

A review of necrotising external otitis, a relatively unknown and dangerous disease, brings out that, initially, it has three characteristics: a granulating necrotising ostitis of the external meatus, extreme pain and a yellowish green secretion. It is always caused by a pseudomonas infection and in almost all cases the patients suffer from diabetes mellitus. If the condition is not recognized in good time and an extensive debridement of the bone involved not performed promptly, ostomyelitis of the base of the skull may follow with involvement of cranial nerves. Severe chronic osteomyelitis of cervical vertebrae occurred in one of our cases. The neurologist must bear this disease in mind in the differential diagnosis when cranial nerves are affected because the nerve disturbances may become evident only after the local condition has subsided or the nerve deficits may be more prominent than and obscure the local ear condition. The most commonly involved nerve is the facial although there may be multiple cranial nerves involved including the third through the twelfth. If the cervical vertebrae become affected there may be nerve root lesions. A torpid meningoencephalitis may also occur. Close cooperation between otologists and neurologists is necessary to recognize and treat these conditions properly.
J Neurol 1975 Sep 22
PMID:[To the differential diagnosis of cranial nerve lesions: the progressive necrotising external otitis (author's transl)]. 5 Oct 78

The effects of human urogastrone (0-25 mug. per kg. per hour intravenously) in four male patients with proven Zollinger-Ellison syndrome (z.e.s.) and in four healthy control subjects have been studied. After urogastrone in z.e.s. patients gastric acid volume and concentration decreased and basal acid output was reduced by 50-82%; the concentrations of intrinsic factor and pepsin in gastric juice increased by 60-300%; and peak plasma-gastrin concentration increased by 127-164% of basal concentration. A significant negative correlation between increase in plasma-gastrin concentration and decrease in acid output was observed (r=-0-72, P less than 0-01). Ulcer pain was relieved 30-60 minutes after the beginning of urogastrone infusion. These results suggest that urogastrone can inhibit the endogenously stimulated acid hypersecretion in z.e.s.
Lancet 1975 Sep 06
PMID:Effect of urogastrone in the Zollinger-Ellison syndrome. 5 Dec 36

Four cases of a painful abdominal syndrome are presented, the pain occurring in the distribution of the medial cutaneous branch of the 7th--12th intercostal nerves. The diagnosis presents difficulties because of severe abdominal pain. In 2 cases the clinical observations were corroborated by EMG findings. The symptoms, physical manifestations, mode of development and therapy are described. The term proposed for the condition is: Syndrome of the Rectus Abdominis Muscle.
J Neurol 1975 Sep 01
PMID:Syndrome of the rectus abdominis muscle: A peripheral neurological condition causing abdominal diagnostic problems. 5 16


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