Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Acute chylous ascites is of idiopathic origin in 50 per cent of cases, the remainder being accounted for by trauma and intestinal obstruction. It usually presents with acute abdominal pain. Neoplastic disease is much more common in chronic cases, and lymphomas comprise about half of these. Chronic chylous ascites usually presents without pain but with inanition and hypoproteinaemia. This report describes acute chylous ascites following trauma in a patient who was subsequently found to have a pancreatic carcinoid, the lymphangiographic findings being of particular interest.
 ...
PMID:Acute chylous ascites with carcinoid of the pancreas. 401 65

The neurosurgeon has many approaches to pain control, depending on the location of the cancer and its tissue characteristics. By far, the most common procedure to be employed is percutaneous chordotomy, which is relatively risk-free and easy for the patient to undergo. It is most important to recognize that pain relief should be effected early in the course of the disease before the ravages of drug addiction and the complications of directed therapy like radiation or chemotherapy have taken their toll. Inanition, under these circumstances, may well be the result of treatment and drugs, rather than the disease itself. We have often seen patients, once given pain relief, make sudden weight gains and go on to a comfortable existence for a surprisingly long period of time thereafter. It is urged that pain relief be considered early, as a major contribution to enhanced quality of living and longevity of survival.
 ...
PMID:Surgical approaches to pain control. 619 74

Anorexia is a symptom seen in the majority of patients with cancer or the acquired immunodeficiency syndrome (AIDS) who experience involuntary weight loss. It is frequently not seen as a symptom requiring management in the same proactive manner as pain, nausea, or constipation. Progressive inanition or wasting is a fundamental component of the complex phenomenon known as the anorexia/cachexia syndrome (ACS) of malignancy or AIDS. Weight loss can be seen in the full spectrum of patient care settings: as a presenting complaint, defining condition, treatment-related toxicity, or as a hallmark of impending death. Primary pharmacologic management of ACS includes use of orexigenic agents (appetite stimulants), anticatabolic agents (antimetabolic and anticytokine), and anabolic agents (primarily hormonal). In addition to these specific categories of pharmacologic intervention, broad aspects of symptom management need to be addressed and are complementary. The available literature evaluating pharmacologic management of ACS in both malignancy and AIDS is reviewed.
 ...
PMID:Pharmacologic management of anorexia/cachexia. 962 82