Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

As many as 348 courses of psychotropic and antianginal chemotherapy were performed for coronary disease confirmed angiographically. Hypochondriac patients were resistant to the drugs, depressive states and anxiety showed the best response. Tranquilizers and neuroleptic agents proved effective in anxiety, neuroleptics in cardiophobia and hypochondria, antidepressants in depression and asthenia. The addition of psychotropic drugs to antianginal therapy produced a positive effect on cardiac pain with antidepressants benefit ranking first, neuroleptics second and tranquilizers third. Being moderate and transient, treatment-related side effects did not cause the treatment discontinuation.
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PMID:[Comparative effectiveness of psychotropic drugs in patients with chronic ischemic heart disease]. 167 31

Cardiophobia, a clinical syndrome that affects hundreds of thousands of individuals in the USA, is characterized by abrupt, recurrent sensations and pain in the chest in the absence of physical pathology. This conceptual article seeks to address the significance of cardiophobia in western culture and to distinguish it from related disorders. In addition, a model of cardiophobia that highlights the role of heart-focused anxiety and interoceptive conditioning in the generation of limited-symptom panic attacks and acute chest pain is presented and vulnerability factors for cardiophobia are discussed. Future research directions relevant to the assessment and treatment of this clinically significant phenomenon are reviewed.
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PMID:Cardiophobia: a critical analysis. 1856 94