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Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This work was done to evaluate the transcutaneous oxygen tension (TcPO2) in ischaemic legs introducing two variables: O2 breathed at 40% and heating with an electric blanket (HEB). Forty nine legs were studied and divided into three different groups: Normal (N) 19 legs, Intermittent Claudication (IC) 12, and Rest Pain (RP) 13. The transcutaneous sensor was placed on the Anterior Chest Wall (AChW), High thigh (HT), Anterior Tibial Compartment (ATC) and Dorsum of the Foot (DF). Measurements were done at each area with and without 40% O2 and with and without HEB. The TcPO2 readings increased significantly (P less than 0.05) in the three groups (N, IC, RP) at all leg levels (HT, ATC, DF) when the patient breathed 40% O2 with and without HEB. In the N group no significant differences were noted between the three leg levels whether the 40% O2 or the HEB was used or not (P less than 0.05). In the RP group significant differences were obtained when the HEB was used whether the patient was breathing ambient O2 or at 40%. On the contrary, when the HEB was not used, the differences between HT and ATC disappeared but persisted at the DF (P less than 0.05). There was a good correlation at the DF and at the AChW (DF/AChW) (r: 0.8012; P less than 0.001). From these results, we conclude that the TcPO2 is a good method of differentiating different degrees of leg ischemia in vascular patients.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Assessment of transcutaneous oxygen tension in ischaemic legs by means of using an electric blanket and 40% O2. 406 35

We treated 107 adults with spinal tuberculosis. The average age was 41.8 years (range, sixteen to seventy-five years). Diagnosis was difficult: bone scans were negative in 35 per cent; gallium scans, negative in 70 per cent; and results of tuberculin skin tests, negative in 14 per cent. Five neurologically impaired patients had no discernible bone lesions when they were first seen but were found to have either intradural or extradural tuberculomas or tuberculous arachnoiditis. Our indications for a spinal operation were neurological impairment, spinal instability, or failure of medical management, and an operation was required in fifty-three of the 107 patients. Anterior decompression and fusion was the surgical procedure of choice. Ninety-four per cent of neurologically impaired patients recovered normal neurological function after anterior decompression; 79 per cent, after non-surgical treatment; and 55 per cent, after laminectomy. Neurological recovery and relief of pain occurred more rapidly in the surgically treated group. Kyphosis did not worsen in any patient, whether treated medically or surgically. There were no organisms that were resistant to isoniazid, rifampin, or ethambutol, and there was neither progression nor reactivation of disease after twelve months of adequate chemotherapy.
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PMID:Tuberculous spondylitis in adults. 407 12

Twenty-one patients suffering from cervical spondylosis and peripheral symptoms underwent uncomplicated anterior interbody fusion of the cervical spine and were re-examined clinically and radiologically at 27 +/- 15 months (mean +/- SD) after the operation. Translatory displacement of the segment adjacent to the fusion level was noted in 14 patients. Its incidence could not be related to the age and sex of the patient, to extent of the fusion, or to postoperative time. Anterior slippage did not correlate with persistent or recurring pain.
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PMID:Instability of the cervical spine after anterior interbody fusion. A study on its incidence and clinical significance in 21 patients. 408 40

Anterior dislocation of the proximal interphalangeal joint is a complex injury involving specific pathomechanics. Progression of this injury to a chronic stage is associated with considerable morbidity in the form of pain, instability, and loss of motion in the involved joint. Surgical reconstruction is complicated and results of delayed intervention are compromised. Two cases of anteriorly dislocated interphalangeal joints, unrecognized as such early and allowed to progress to a chronic stage, presented to us as boutonniere deformities. Descriptions of clinical presentation, surgical findings, and treatment results in these cases attest to the disabling potential of this injury. Emphasis is therefore placed on early recognition of the anteriorly dislocated proximal interphalangeal joint so that appropriate treatment can be initiated and progression to a chronic stage prevented.
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PMID:Chronic anterior dislocation of the proximal interphalangeal joint. 409 81

Anterior interbody fusion of the lumbar spine by the extraperitoneal technique was performed in 47 patients with incapacitating low-back pain due to spondylolisthesis (26 patients) or disc degeneration (21 patients). The mean age was 38.2 years. Forty-five patients were re-examined 2--6 years postoperatively. According to the patients' own evaluation at follow-up, 53 per cent were free or almost free of back pain, 29 per cent were improved, 11 per cent unchanged and 7 per cent felt that the condition had deteriorated. Non-union occurred in nine patients, but among these three were free of pain, four were better and two were worse than before operation. The results do not seem to be correlated with age, sex, duration of pain before operation, degree of slipping in spondylolisthesis or the length of time out of work before surgery. It is concluded that this method may be worth continuing, but the patients should be selected with care.
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PMID:Anterior interbody fusion of the lumbar spine. 621 35

Age-related differences in sensitivity to pain as induced by heat and electrical shock were seen among groups of rats; 2-3, 6-12, and 24 months of age. These are differences were at least partially obliterated by naloxone treatment, suggesting that changes may occur in the endogenous opioid system during aging. In contrast to higher pain thresholds in older animals, however, are decreased concentrations of opiate receptors in the frontal poles, striatum and hippocampus. Anterior cortex and amygdala exhibit a trend toward decreased concentration with increased age, but this is not significant. No age changes in binding affinity occur in any of the brain regions examined. Possible explanations for the apparent discrepancy between altered receptors and response include: higher endogenous opioid levels in aged rats, mediation of pain sensitivity by brain regions other than those examined, difficulties inherent in attempting to localize age changes at a single step in such a complex process, and possibly differential spinal pathways mediating the various types of pain.
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PMID:Effect of age on sensitivity to pain and brain opiate receptors. 626 93

Pain is the major cause for surgical intervention in adults with scoliosis and it accounts for 65% of cases. With improved techniques of surgery, including anterior approaches, and better diagnostic methods, including the use of diskography, the satisfactory results of surgical correction have improved from 65-75% to 85-90% of the reported cases. Anterior instrumentation has resulted in decreased pseudarthrosis rates and reduction of lumbar lordosis deformities.
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PMID:Recent advances in the treatment of painful adult scoliosis. 644 51

We reviewed the cases of forty-eight patients who were treated surgically for symptomatic post-traumatic kyphosis of the thoracic or lumbar spine six months or longer after the initial injury. Presenting signs and symptoms included pain in 94 per cent, progression of kyphosis in 46 per cent, instability in 36 per cent, and increasing neural deficit in 27 per cent. Twenty-four patients had had a prior laminectomy. Posterior fusion (sixteen patients) and combined anterior and posterior fusion (twenty patients) always resulted in primary fusion. Anterior fusion alone was attempted in twelve patients, but failed in six. The average final correction of the deformity was 26 per cent. Pain was reduced significantly in 31 per cent of the patients and was relieved completely in 67 per cent. Fourteen of the forty-eight patients also had an anterior decompression, of whom five were neurologically improved, four were unchanged or stabilized, and four were immediately worse after operation. One patient was neurologically stable for twenty-three months postoperatively and then deteriorated again. No patients were neurologically improved following posterolateral decompression or repeat exploratory laminectomy.
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PMID:Post-traumatic kyphosis. A review of forty-eight surgically treated patients. 645 78

Eighty young athletes with weight training-related injuries were seen from August 1976 to August 1980. In 37 of the 80 athletes, it was difficult to pinpoint the cause of injury since the history revealed, in addition to weight training, either a program of running excessive mileage or participation in repetitive lap running in the gymnasium. The injuries of the remaining 43 athletes had a direct causal relationship to the weight training program. Twenty-nine developed lumbosacral pain. Seven of the 29 were hospitalized, and four required surgical treatment. Anterior iliac spine avulsion occurred in six cases, and laceration of the knee meniscus occurred as an initial injury in four athletes who required surgery. Four athletes developed a cervical sprain. Universal Gym (Cedar Rapids, IA), Leaper (Strength/Fitness Systems, Independence MO) Orthotron (Lumex Inc., Bay Shore, NY), and free weights were used either singly or in combination by these young athletes in weight training.
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PMID:Weight training-related injuries in the high school athlete. 645 35

Lateral transcranial TMJ radiographs are duplicable within +/- 0.2 mm and are cross-sectional views of the lateral third of the condyle and fossa. The innate asymmetry of humans, when the right and left sides of the fossa and condyle are compared, was clinically insignificant. Tomograms are not indicated because they lack appropriate resolution and detail to evaluate qualitative bone changes; and because they are not an in-office procedure, the condylar position in the fossa is completely unreliable. A correlation was reported between condylar position in the fossa and TMJ dysfunction in over 320 patients. This observation suggests that a new definition of centric relation is indicated, a definition that differentiates whether it is functional or dysfunctional. The criterion is the correlation between the occlusal findings and the condylar position in the fossa as recorded by the lateral TMJ radiographs (when the teeth are in maximum occlusion). Stress response was found to be greater in males than in females (in all vertebrates, including humans); therefore stress cannot be a direct cause of craniomandibular pain since more women have the disorder. It was concluded that stress is an indirect contributing factor that usually works through the medium of clenching. The role of the neuromuscular mechanism in craniomandibular pain was discussed. Proprioception reflex activity forms the basis for muscle length, mandibular positional sense, as well as masticatory function. Occlusal disharmonies increase noxious input to the neuromuscular system, as well as stress-induced clenching, causing increased muscle activity and spasm-pain. Condylar displacement also contributes to TMJ dysfunction-pain, depending on its direction. Anterior condylar displacement can initially affect the muscles by inducing overfunctional response in the proprioceptive system. Posterior condylar displacement usually results in an intrajoint response consisting of a disk derangement, reciprocal clicking, possible anterior disk dislocation, possible pathologic swallowing pattern, and noxious stimulation to the proprioceptive system. These factors contribute to subsequent trismus, muscle spasm and pain, and long-term pathologic remodeling of the joint. A detailed history is necessary to evaluate the role of stress. The physical occlusal findings are correlated with the condylar displacement observed in the TMJ radiographs to diagnose and plan corrective treatment.
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PMID:The role of stress, occlusion, and condyle position in TMJ dysfunction-pain. 657 1


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