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Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 52-year-old man presented with an extremely rare case of synovial chondromatosis in the temporomandibular joint (TMJ) with extension into the middle cranial fossa manifesting as swelling and exacerbation of pain. He had a long history of right TMJ disorders. Computed tomography and magnetic resonance imaging showed a mass in the right TMJ with extension into the intracranial part through the destroyed temporal skull base. The preoperative diagnosis was chondrosarcoma or osteosarcoma. The patient underwent surgery via combined trans-zygomatic temporal skull base and pre-auricular approaches and the mass was totally removed. Histological examination found an enormous number of closely packed loose bodies of various sizes, consisting of hyaline chondrocytes. The histological diagnosis was synovial chondromatosis. This rare lesion is difficult to discriminate from chondrosarcoma, so total removal is essential for correct diagnosis and cure.
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PMID:Synovial chondromatosis of the temporomandibular joint with intracranial extension. 1857 34

Synovial chondromatosis is an uncommon disorder characterized by the formation of multiple cartilaginous nodules within the synovium and most commonly affects large joints, such as the knee and hip. Diagnosis in synovial chondromatosis is generally confirmed by histology after clinical and radiologic examination. Diagnosis may sometimes be difficult because synovial chondromatosis resembles a soft-tissue mass and may give no radiologic findings. We describe a case of synovial chondromatosis stemming from the subtalar joint, in which diagnosis was difficult clinically and radiologically. The patient presented with pain in the ankle and with a soft-tissue mass. This case is presented with a review of the literature on subtalar joint involvement of synovial chondromatosis.
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PMID:Synovial chondromatosis of the subtalar joint: a case report and review of the literature. 1868 54

A 62-year-old female patient suffered from numbness and resting pain in the right ring and little fingers for 3 years. We confirmed cubital tunnel syndrome with electrodiagnostic study and performed the operation. We found seven firm consistent nodules, compressing the overlying the ulnar nerve, proximal to the medial epicondyle in the operation field. Histological finding showed synovial chondromatosis. We report a rare case of a patient with cubital tunnel syndrome caused by synovial chondromatosis.
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PMID:Cubital tunnel syndrome, associated with synovial chondromatosis. 1909 14

We describe a case of primary articular synovial chondromatosis in a metacarpophalangeal (MCP) joint of a 48-year-old male. The patient initially presented with MCP joint swelling and pain with normal plain radiographs. Following a fourteen month course of conservative management, surgical debridement of the joint revealed multiple loose bodies consistent with primary articular synovial chondromatosis. Though synovial chondromatosis rarely occurs in hand joints, the diagnosis should be considered in cases of metacarpophalangeal pain when common etiologies have been excluded.
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PMID:Metacarpophalangeal joint synovial osteochondromatosis: a case report. 1922 57

Synovial chondromatosis is an uncommon lesion of unknown etiology, characterized by progressive metaplasia associated with the formation of cartilage in the synovial membranes of joints, tendon sheaths, or bursae. Synovial chondromatosis is typically monoarticular and affects large joints such as the knee and hip, although it has also been described in the ankle, elbow, and shoulder. However, it rarely occurs in the wrist. Our literature review showed only 28 cases with wrist involvement, 13 cases with distal radioulnar joint involvement, 12 cases with midcarpal joint involvement, and 3 cases with radiocarpal joint involvement. This article presents a case of synovial chondromatosis of the radiocarpal joint. A 45-year-old right-handed woman presented with a 4-year history of a palpable mass and pain in her right wrist. On physical examination, 2 masses were palpable on the volar and radial aspect of the joint. Plain radiographs of the right wrist demonstrated well-defined radiopaque calcified mass lesions. Cortex and subcortical bone on the radial aspects of the radius and scaphoid were eroded. T1-weighted magnetic resonance imaging (MRI) showed a low-signal-intensity lesion, and T2-weighted MRI showed a heterogeneous high-signal-intensity lesion in the radiocarpal joint, which was consistent with synovial chondromatosis. Operatively, 2 glistening white lobulated masses were removed together with attached synovia. A histologic examination confirmed synovial chondromatosis with dystrophic calcification. At the time of the most recent examination (3 years postoperatively), the patient was pain-free, had no residual motion deficit, and showed no radiographic evidence of recurrent disease.
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PMID:Synovial chondromatosis of the radiocarpal joint. 1929 8

A case of synovial chondromatosis originating from the synovium of the anterior cruciate ligament (ACL) resulting in a mechanical block to knee extension is reported. A 36-year-old man complained of a restricted range of left-knee motion and pain when walking. Plain roentgenograms showed normal appearance, however, magnetic resonance imaging showed intensity changes in the ACL. Arthroscopically, numerous small free bodies were observed. Proliferation of synovium and cartilaginous tissues were identified around the ACL. There were no significant findings in the synovium except around the ACL. The synovium around the ACL was resected and free bodies were washed out. This is the first report of synovial chondromatosis originating from the synovium of the ACL.
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PMID:Synovial chondromatosis originating from the synovium of the anterior cruciate ligament: a case report. 1938 35

Chondromyxoid fibroma is a rare benign bony tumor classically occurring in the metaphyseal region of the long bones surrounding the knee, but also found with relative frequency in other long bones, the pelvis, ribs, and small foot bones. The small bones of the hand, however, are rarely involved. The tumor is considered a physeal plate remnant and may involve the epiphysis, diaphysis, or both along with its metaphyseal origin. It may cause cortical expansion and destruction, but consistently respects the periosteal boundary. We report a case of histopathologically confirmed chondromyxoid fibroma involving a metacarpal, proximal phalanx, and synovial tissues of the metacarpophalangeal joint. A 29-year-old woman presented with pain, weakness, and a mass of the right ring finger metacarpophalangeal joint that had persisted since prior surgery to remove an extraosseous chondroma. Prominent soft tissue swelling and limited range of motion were noted, corresponding to magnetic resonance imaging findings of lytic changes in the right ring finger metacarpal and proximal phalanx, surrounded by an irregularly enhancing mass with soft tissue extension. Open biopsy revealed calcified cartilaginous synovial deposits suspicious for synovial chondromatosis, with erosion into surrounding bones. Histologic examination revealed an unusual chondromyxoid fibroma with joint involvement. The patient is >15 months out from synovectomy, intralesional curettage, and placement of demineralized bone matrix and allograft cancellous chips, and is without signs of recurrence. This benign, curable lesion should be included in the differential diagnosis of a bony lesion, even when a joint and adjacent bones are involved.
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PMID:Chondromyxoid fibroma involving the metacarpophalangeal joint. 1938 7

This article reports a rare case of a temporomandibular joint (TMJ) chondrosarcoma in a child. Chondrosarcoma is a malignant cartilaginous neoplasm that resembles synovial chondromatosis. In the head and neck region, chondrosarcoma is uncommon, corresponding to 6.4% to 12% of all reported cases. The majority of patients with chondrosarcoma are in the third to fourth decades of life. A Pubmed search showed that 20 TMJ chondrosarcoma cases had been reported up to 2008. The present case was of an 11-year-old girl referred to an Oral Disease Center and presenting with a preauricular swelling on the right side and normal ENT evaluation. The patient was healthy. Discrete pain and mild limitation of mouth opening were observed. A panoramic radiograph as well as computed tomography (CT), ultrasound, and magnetic resonance imaging (MRI) revealed an osteolytic lesion in the right TMJ. The skull base and adjacent spaces were preserved but adjacent anatomic structures were displaced. After an incisional biopsy, the patient underwent high condylectomy. Microscopic findings showed a tumor exhibiting cartilaginous tissue proliferation with cellular pleomorphism, nuclear hyperchromasia, and mixoid changes in the matrix. The immunohistochemical analysis of the expression of Ki-67 and Cyclin B1 proteins (cellular proliferation markers) revealed a very low proliferative cell index. The 3.5 years of clinical and imaging follow-up have shown no evidence of recurrence or metastasis, but signs of myofascial disorders could be observed. It is concluded that cartilaginous lesions in the jaws must be regarded with suspicion, since benign and malignant lesions may show similar clinical features. This case emphasized the importance of interdisciplinary approaches to minimize the possibility of misdiagnosis.
J Orofac Pain 2009
PMID:Chondrosarcoma of the temporomandibular joint: a case report in a child. 1963 7

Background. This article describes a case of chondromatosis of the elbow in a 33-year-old male patient. An arthroscopic method was used to remove multiple loose bodies from the joint.<br /> Case history. The patient complained of pain in the right elbow. He presented with edema in the elbow joint, pain during movement, occasional slippage, and a 300 functional reduction in elbow extension.<br /> Procedure. After the arthroscope was introduced into the joint, numerous loose bodies were detected, covered with cartilage, pale pink synovial membrane with hyperthropied villi. The cartilage of the joint surfaces bent slighty under pressure: however, there was no sign of decay, destruction, or deep deficits. Using a punch and Pean forceps we removed ca. 20 loose chondral and condro-osseous bodies ranging in diameter from 0,3 to 2,0 cm.<br /> Outcome. There were no post-surgical complications. After several days the patient was discharged. Within a week he recovered a full range of motion in the joint and no pain. The patient continues to work in a job demanding physical exertion and plays volleyball.<br /> Conclusion. Arthroscopy of the elbow is a good solution for the problem of loose bodies in the elbow joint, especially when they occur in both sections of the joint, where classical surgical techniques require two routes of surgical access or two-phase surgery.
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PMID:Arthroscopic management of chondromatosis of the elbow: a case report. 1977 42

Synovial chondromatosis is a chronic, progressive disease of the synovial tissue where free chondral loose bodies are formed after metaplasia. It is mostly seen as a monoarticular disease in the knee, hip, shoulder, ankle, and elbow joints. To our knowledge, isolated synovial chondromatosis of the proximal tibiofibular joint has not been reported. A 36-year-old male patient presented with a complaint of pain on the lateral side of the right knee, whose severity gradually increased within the past two years. Radiological findings were suggestive of synovial chondromatosis of the proximal tibiofibular joint. The patient was treated with resection of the fibular head, including the satellite lesions. Histopathological examination confirmed the diagnosis. At one-year follow-up, the patient was symptomless, had full range of motion of the knee without pain, and had no problems in maintaining daily activities. Pathologies of the proximal tibiofibular joint must be kept in mind in patients with lateral knee pain.
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PMID:[Isolated synovial chondromatosis of the proximal tibiofibular joint]. 1988 28


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