Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors report the results of treatment with a modification of acupuncture associated with chemical stimulation in 144 patients with painful radicular syndromes and headaches. In 57 cases sciatic pains were present, in 21 cases shoulder pains, in 20 migraine and in 46 vasomotor headaches. Permanent disappearance of pain, that is disappearance of pain during the procedure and lack of recurrence within several successive days, was obtained in about 40% of cases of radicular syndromes and in 62% of cases of headaches, early disappearance of pain for 3 to 48 hours after the procedure was obtained in 14% of radicular syndromes and nearly 26% headaches, while improvement, that is reduction of pain intensity, was achieved in 29.5% of radicular pains and 3% of headaches, while in 15.3% of cases of radicular syndromes and 9% of cases of headaches no improvement was observed. Both vasomotor headaches and neuralgias belong to the group of nervous system diseases in which pain is the basic and sole symptom, while treatment includes its removal. In these cases acupuncture is a valuable analgesic method. The presently reported results agree with those in the literature on the use of classical acupuncture and its modifications. It is worth stressing that insertion of needles into the traditional points used in classical acupuncture is without any greater importance was shown by the presently reported experiences (various points were used in the same case) as well as by the reports of other authors. The modification of acupuncture with addition of chemical stimulation has been tried by the authors for 4 years. A weak stimulus resulting from insertion of the needle and irritation of the nerve endings with concentrated sodium chloride acts similarly as mechanical or electrical irritation. The method is simple and completely safe.
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PMID:[Modified acupuncture in the treatment of pain]. 68 27

CBF was studied in 15 cases of vascular headache by the 135Xe intra-arterial injection method. The mean CBF was found to be increased during the headache phase of the migraine attacks in half the cases, mainly due to an increase in the rapid component (CBFg). After the attack there could be an increase or a decrease of the slow component (CBFw). Reactivity to anaesthetic depression was studied in 8 migraine cases and on the whole it was found not to be much altered in most cases. Finally, no modifications of CBF were found in any of 3 cases of cluster headache who were studied during attacks of severe pain.
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PMID:Cerebral blood flow in migraine and cluster headache. Compartmental analysis and reactivity to anaesthetic depression. 72 60

The relief of acute migraine attacks with an analgesic/antihistamine combination containing paracetamol, codeine phosphate, doxylamine succinate and caffeine (Mersyndol) compared with that achieved with a placebo has been studied in a double-blind, crossover trial. Mersyndol emerged as significantly better than placebo in the complete relief of migraine pain, and was clearly superior to placebo in partially relieving the pain of migraine. These results suggest that it could be a useful alternative to ergotamine, and a comparative trial with ergotamine is suggested. Side effects with this combination were fairly common but mild, and consisted mainly of drowsiness caused by the antihistamine component.
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PMID:Treatment of migraine attacks with an analgesic combination (Mersyndol). 78 38

In migraine patients a considerable metabolic disturbance characterised by a decrease in bicarbonate and in increase in lactate was demonstrated during the migrainous status. Measurements of the cerebral circulation were taken by means of radioactive isotopes and showed a distinct decrease in blood supply to the entire brain during the migraine attack. Following forced hyperventilation during the attack-free interval a pathological reactivity with decreased blood flow was found in the hemisphere which had been indicated as the usual site of the migrainous pain.
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PMID:[Cerebral blood flow (measured by means of isotopes) and base-acid-equilibrium of the CSF in migraine (author's transl)]. 81 Jun 79

35 patients suffering from different painful conditions were treated with transcutaneous application of a slightly painful electrical stimulus. The effect was manifested in complete relief in six patients treated during an attack of migraine and in a relatively high number of other cases of headache with relief of pain. In some cases there was a long-lasting favourable effect for periods up to 8 months. For the theoretical explanation the 'gate control' theory is referred to. With respect to the practical application, the special indication in cases of chronic headache is emphasised, especially since this method avoids the risks of habit-formation or other damaging effects of drug therapy.
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PMID:[Transcutaneous nerve stimulation for the treatment of migraine and other head pain (author's transl)]. 81 29

The new migraine preparation Migraeflux has been subjected to clinical trial in a double-blind cross-over study in 32 single tests. Compared with other products, the 2-phase-preparation Migraeflux is distinguished--due to its antihistaminic ingredient--by the capacity of preventing in 2/3 of the cases the formation of a migraine attack if applied soon during the prodromal phase. If the attack is not prevented, the intensity of pain is lessened in 70% of the remaining cases and the duration of attack is markedly reduced. The preparation proved to be tolerated very well.
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PMID:[Therapy of migraine. Clinical experience with Migraeflux, a new migraine drug]. 83 30

We describe seven patients with vascular headaches. Five of them had cluster headaches, which were preceded by migrainous scotamata (two patients), weakness contralateral to the pain (one), accompanied by ipsilateral photopsias (one), or by contralateral paresthesias (one). The other two patients had "clusters" of daily common migraine headaches separated by long free intervals. The symptoms of these patients suggest a common root for cluster and migraine headaches.
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PMID:The clinical link between migraine and cluster headaches. 88 78

This paper indicates that the sources of migraine have always been in doubt, from ancient times when physicians first described the syndrome of migraine without clarifying it sources to the present day when physicians, still in some doubt, contend that excess of such substances as acetylcholine or serotonin may trigger the migraine. This paper argues that dynamic binocular seeing, normally a stress function, excites the migraine headache, primarily, howver, among visual pain sensitive individuals. Cases are offered whose migraine is relieved by creating a finer binocular seeing balance through fusion-eye movement training with the V.T. Reading Aid.
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PMID:Migraine: fusional-eye movement stress. 90 28

The effect of cephalic vasomotor response (CVMR) and frontalis electromyographic (EMG) feedback on control of temporal arterial vasoconstriction and frontalis muscle activity in migraine and muscle contraction headache patients was investigated. A single subject multiple baseline design (across subjects and responses) was introduced to evaluate (1) patterning in the two physiological systems and (2) the effects of CVMR and EMG feedback on headache activity. The data indicated that (a) all four patients demonstrated an ability to control CVMR activity during CVMR feedback and EMG during EMG feedback, (b) idiosyncratic patterns of physiological activity emerge during feedback training, and (c) learned control of the pain mechanism for muscle contraction and migraine headaches was related to reduced frequency and duration of these headaches.
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PMID:Cephalic vasomotor feedback in the modification of migraine headache. 92 58

In migraine patients a considerable metabolic disturbance characterised by a decrease in bicarbonate and an increase in lactate was demonstrated during the migrainous state. Measurements of the cerebral circulation were taken by means of radioactive isotope and showed a distinct decrease in blood supply to the entire brain during the migraine attack. Following forced hyperventilation during the attack-free interval a pathological reactivity with decreased blood flow was found in the hemisphere which had been indicated as the usual site of the migrainous pain.
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PMID:[Cerebral circulation (measured by isotopes) and acid-base equilibrium of the cerebrospinal fluid during migraine]. 93 48


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