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 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Developmental Orthopaedic Disease (DOD) in limb joints of horses is frequent and is a common cause of pain and lameness. DOD is a multifactorial disease involving genetics, growth, feeding practices and exercise conditions leading to joint injuries. However, there is no clear understanding of the contribution of each factor. The aim of this cohort study was to assess the adjusted effects of breed and gender, growth, feeding practices and exercise conditions on the prevalence of DOD in the limbs of foals at weaning and on the prevalence restricted to osteochondrosis (OC). Twenty-one farms in Normandy, France, were convenience sampled and enrolled in a cohort study. The study sample consisted of 401 foals from 3 breeds, followed from the 8th month of pregnancy of the mares until weaning period at approximately 6 months of age of the foals. Stud farms were regularly visited to collect growth, feeding practices and exercise conditions data. The carpus, the front and hind digits, the hock and the stifle of the foals were X-rayed at the end of follow-up. Foals were categorised as affected or unaffected by DOD or by OC. Two mixed-effects logistic regression models were used to determine risk factors for DOD or OC, adjusting for clustering by farm. Of the 378 foals with complete data, 47% (95% CI: 42-52) were affected by DOD and 36% (95% CI: 31-41) by OC. Risk was significantly increased for DOD and for OC in Warmblood foals compared to Thoroughbreds (OR 2.8; 95% CI: 1.2-6.5 for DOD, OR 2.9; 95% CI: 1.1-7.5 for OC), in foals with a high wither height at 30 days of age, and in foals with a rapid increase of wither height (for DOD only). Exercise conditions such as large area of pasture, some irregular exercise, or some batch changes were also significant risk factors for DOD or OC. No association was found with quantitative feeding practices; it was likely due to the limited variability of horse regimens and to the partial inclusion of nutritional effects in other factors such as breed and growth. In order to reduce the prevalence of DOD or OC in foals, following the growth and reducing nutritional supply in subjects growing fast, limiting the pasture areas offered and providing a regular exercise to foals seems appropriate. To our knowledge, to date the assessment of adjusted effects of potential risk factors for DOD has never been proposed.
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PMID:Association of growth, feeding practices and exercise conditions with the prevalence of Developmental Orthopaedic Disease in limbs of French foals at weaning. 1932 2

Two young adult male castrated German Shepherd Dogs were referred for evaluation of intermittent episodes of hindlimb pain. Physical examination suggested lumbosacral stenosis, and plain radiographs and computed tomography revealed lesions consistent with sacral osteochondrosis. One dog had osteochondral fragments removed surgically; the other was managed conservatively. The surgically treated dog had complete resolution of clinical signs whereas the dog managed conservatively had repeated episodes of mild pain and received one short course of non-steroidal anti-inflammatory medication in 18 months. Sacral osteochondrosis has not been previously reported in Australia.
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PMID:Sacral osteochondrosis in two German Shepherd Dogs. 1948 84

The article deals with an investigation of therapeutic efficiency combined with applications of biological preparations and special medical-improving gymnastic exercises at treatment of a vertebral cervical osteochondrosis on the one hand, traditional means on the other hand. 76 patients aged 31-62 have taken part in the given research. The basic group was made by 47 patients and the control group - by 29. The patients of the basic group applied a special complex of medical-improving gymnastic exercises, and also paravertebral injections of biological preparations Traumeel S, Neuralgo-Rheum-Injeel. The patients of the control group received traditional therapy of a vertebral osteochondrosis. Injections of Voltaren (Diclofenac) intramuscularly, MIG400 (Ibuprophen) tablets, phonophorez with Indometacin ointment, a traditional complex of physiotherapy exercises. Duration of the treatment in all groups has made 28 days. Obtained data testify that by the end of treatment full knocking over of a pain syndrome in the basic group is noted at 71,2 % of patients, in control group only in 41,4 % of patients the pains have completely disappeared in a cervical spine. Thus, therapy by biological preparations in a combination to a complex of special medical-improving gymnastic exercises allows to reduce terms of knocking over of sharp clinical displays of an osteochondrosis of a cervical spine, to raise efficiency of restoration of sensitive, vascular, muscular-tonic frustration, and also allows to avoid neuro-surgical intervention at patients with hernias interspine disks.
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PMID:[The complex approach to treatment of pain syndrome of cervical vertebral osteochondrosis]. 1955 39

A total of 136 patients with clinical symptoms of thoracic osteochondrosis and reflex vertebrocardiac disorders were examined. 100 of them presented with vertebrogenic cardialgia and CHD, 36 had no CHD. 56 patients with clinical symptoms of thoracic osteochondrosis and CHD received traditional therapy and a course of intraosseous blockade (IOB). 56 patients with clinical symptoms of thoracic osteochondrosis and CHD received traditional therapy and a course of paravertebral blockade (PVB). 36 patients with clinical symptoms of thoracic osteochondrosis without CHD received a course of IOB. Efficiency of therapy was assessed from dynamics of pain syndrome parameters, data of the visual analog scale, McGill and body diagram questionnaires, changes of cardiac function and heart rhythm recorded by 24-hr Holter monitoring. Therapeutic efficiency of IOB in patients with vertebrogenic cardialgia with and without CHD was higher than that of PVB in patients with clinical symptoms of thoracic osteochondrosis and CHD. It is concluded that osteogenic factor plays a key role in the mechanism of development of vertebrogenic cardialgia.
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PMID:[Osteogenic factor in pathogenesis of vertebrogenic cardialgia]. 1956 26

Freiberg's infraction is not widely seen but can occur among young athletes. Its symptoms and radiographic signs may mimic stress fractures, as in the 12-year-old female dancer described here. This condition, an osteochondrosis that most commonly affects the second metatarsal, is diagnosed with plain radiography. Treatment typically involves immobilization or off-loading to eliminate pain, use of orthoses, and a gradual return to weight-bearing activity.
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PMID:Freiberg's Infraction in an Adolescent Dancer: Condition Often Mistaken for a Stress Fracture. 2008 55

Osteochondritis dissecans of the humeral capitellum is an unusual, but not rare, complication of repetitive stress to the skeletally immature elbow. This case report of a Little League player demonstrates how untreated underlying osteochondrosis resulted in permanent disability. Radiographs are essential. The differential diagnosis includes infection, cysts, and Panner's disease. For nondisplaced fragments, rest is indicated until pain resolves and range of motion returns; surgery or arthroscopy may be needed to remove or repair displaced fragments.
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PMID:Osteochondritis dissecans in a young pitcher: why early recognition matters. 2008 94

Osteochondral lesions in children mainly occur in the physeal and epiphyseal cartilage. Osteochondritis dissecans and osteochondrosis (apophysitis) are common and clinically important chronic disorders. These etiology and pathogenesis have also been well investigated in the Veterinary medicine in recent years. One of the most likely causes is proposed as a failure of blood supply to growth cartilage and following focal disturbance of endochondral ossification. Mechanical stress, trauma, rapid growth, anatomic conformation, and dietary imbalances would modify this initial step and break down the normal structure. In human, above-mentioned pathological changes can be detected using recent MRI technology, which contribute quite much in the early diagnosis of lesions in clinic. Another problem in children is acute traumatic growth plate injury, which increases the risk of the early closure of growth plate and following deformity of bone and joint. Early diagnosis and precise treatment are extremely important for children to prevent residual deformity and pain and growth disturbance. In future, less-invasive as well as effective treatments for the focally disturbed or accelerated ossification should be developed.
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PMID:[Bone and joint diseases in children. Etiology and pathogenesis of osteochondral lesions in children. Osteochondritis dissecans and osteochondrosis]. 2051 42

We report two cases with radiographic appearances of osteochondrosis in the proximal phalanx of the big toe in adolescent footballers. The radiological findings were those of initial fragmentation with subsequent healing of the epiphysis. This is the first report of osteochondrosis at this site. Local pain was accompanied by swelling with restriction of dorsiflexion of the metatarsophalangeal joint of the big toe. The condition was self-healing over a 2-4-year period. It needs to be included in the differential diagnosis of painful hallux in adolescent footballers.
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PMID:Osteochondrosis of the proximal phalanx of the hallux in adolescent footballers. 2054 53

The effect of two methods of the treatment (traditional and in combination with lascropuncture infrared radiation and manual therapy) on clinical symptoms of vertebral refractory pain syndroms was studied in 120 patients with neck-pectoral osteochondrosis. The empirical knowledge confirmed the necessity of expediency of these methods in the treatment of this pathology.
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PMID:[Infrared laser puncture and manual therapy in the treatment of cervical and thoracic osteochondrosis and neurological manifestations of this disease]. 2060 35

This paper deals with the problems of pelvic girdle asymmetry in patients with spinal osteochondrosis. Effectiveness of medicamentous and rehabilitative treatment of such patients is compromised by destructive changes in the vertebrae. Analysis of locomotor disturbances and their dynamics under effect of remedial gymnastics prescribed on an individual basis showed that the main factor limiting success of osteochondrosis therapy is muscular disbalance in the pelvic girdle. This dictates the necessity to start prevention or treatment of the disease and rehabilitation of the patients from the correction of muscular asymmetry. The muscular corset should be formed so as to ensure dynamic equilibrium of muscular tone (between antagonist muscles) bearing in mind that disbalance in the tone of flexor and extensor muscles (both homo- and contralateral ones) contributes to recurring pain syndrome and further aggravates pelvic asymmetry. Its correction in due time constitutes a major condition for the prevention of diseases affecting not only joints of the lower extremities but also lumbar spine especially in patients subject to intense occupational and sports exertion.
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PMID:[Problems of pelvic girdle asymmetry in patients with spinal osteochondrosis and remedial gymnastics]. 2108 9


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