Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

With a varied presentation and a difficult preoperative diagnosis, schwannoma accounts for only a small percentage of retroperitoneal tumors. Moreover, malignant schwannoma of the adrenal gland, kidney and renal pelvis has previously been described. We report the first case of benign schwannoma causing obstruction by external compression of the ureteropelvic junction. A case report of a male patient who complained of a 3-month history of dull lumbar pain on the right side is reported. Using intravenous pyelogram, sonography and computed tomography a benign tumor of the retroperitoneum was suspected. Upon exploration, the suspected diagnosis of the tumor's retroperitoneal origin was confirmed. After the histological and immunohistochemical studies the diagnosis was verified. The diagnosis, treatment and histological features of benign schwannoma are discussed. A brief review of the literature is also included.
 ...
PMID:Benign schwannoma surrounding and obstructing the ureteropelvic junction. First case report. 926 44

We describe the case of a 46-year-old male patient who presented with pain in the left thigh, often accompanied by lumbar pain. These symptoms were sustained by a neoplasm, which was located in the sympathetic ganglia, at the level of the 3rd left lumbar spinal root and which was completely excised. Immunohistochemical positivity for S100, HMB45, and NSE antibodies suggested that the lesion was a melanotic schwannoma (MS), with both schwannian and melanocytic differentiations, the latter containing melanosomes at ultrastructural examination. Non-recurrence after 16 months of follow-up further supports our diagnosis of MS.
 ...
PMID:Melanotic schwannoma of the sympathetic ganglia: a histologic, immunohistochemical and ultrastructural study. 926 52

Epidermoid cysts are rare intradural extramedullary tumors. There are two types of lesions: congenital spinal cysts frequently associated with other bone or skin malformations (spina bifida aperta, dermal sinus ...) and iatrogenic spinal cysts resulting from lumbar puncture. In both situations, clinical and the radiologic findings are similar. We describe an epidermoid cyst in a 52-year-old female affected with a lumbar pain and recent urinary disorders. Symptoms were slow to appear and dependent on the location of the cyst. Epidermoid cyst contained keratin, cholesterol crystals and desquamed epithelial cells. On CT, epidermoid cyst was a hypodense lesion on MR. On T1 weighted images the tumor was hypointense. The signal appeared heterogeneous. There was no enhancement after Gadolinium DTPA injection. Differential diagnosis included: ependymoma, hemangioblastoma, neurinoma, meningioma and metastasis, but all these lesions are enhanced by contrast injection.
 ...
PMID:[Intraspinal epidermoid cyst]. 930 46

A case of a 46-year-old woman with a left cavernous sinus hemangioma is reported. The onset of symptoms consisted in left orbital pain and ocular diseases. The suspected diagnosis were among Tolosa-Hunt syndrome and, after neuroimaging researches, cavernous sinus meningioma, trigeminal neurinoma, craniopharyngioma and adenoma with extrasellar extension. The lesion was partially removed with additional neurological deficit of the left 3rd cranial nerve. The patient underwent 7 months later focal radiation therapy of 45 Gray and a 19 months follow-up showed the complete disappearance of the mass and partial recovery of the 3rd cranial nerve function.
 ...
PMID:Cavernous hemangioma of the cavernous sinus. Complete disappearance of the neoplasma after subtotal excision and radiation therapy. Case report. 938 72

Neurinomas are the most common intradural extramedullary tumors of the spine. Together with meningeoma they account for 80% to 90% of all tumors in this compartment. Radicular pain is the initial symptom in the majority of cases while motor disorders are less common and occur later in the course of the disease. We report a patient with spinal neurinoma and calf pain as the only presenting complaint. The differential diagnosis in this case required an interdisciplinary approach.
 ...
PMID:Lumbar spinal neurinoma presenting with nocturnal pain. A case report. 942 58

The authors present a patient who had long-term improvement of a severe upper limb action tremor after chronic cortical stimulation. A 40-year-old woman complained of facial pain and tremor of the left arm after removal of an acoustic neurinoma. A motor cortex stimulation was performed to treat the deafferentation facial pain in 1993. Chronic cortical stimulation induced complete relief of both pain and tremor and allowed the patient to recover functional capacity of the limb. These effects persisted throughout a 32-month follow up. Differential effects on pain and tremor were observed when parameters of stimulation were varied, suggesting different mechanisms for the relief of pain and tremor. Attention was focused on control of the tremor. This effect could be the result of the inhibition of subcortical structures which are involved in tremor. Chronic cortical stimulation appears to be an effective treatment for controlling severe action tremors.
 ...
PMID:Improvement of action tremor by chronic cortical stimulation. 945 31

Forty-one patients with a symptomatic digital mass or swelling of suspected ganglionic origin were examined by ultrasound. Findings were classified into 4 groups: group 1, solitary cyst appearing as a well-defined solitary oval anechoic mass (27 digits); group 2, multiple cysts having multiple oval anechoic masses (3 digits); group 3, solid tumor indicating a heterogeneous hypoechoic mass (6 digits); and group 4, tenosynovitis with no abnormal echoic mass (5 digits). Treatment was determined by lesion classification. In group 1, 26 of the 27 solitary cysts were punctured, and a jellylike material was aspirated from 24 cysts. Postaspiration ultrasound examination revealed that a cyst was still present in 2 cases, and these were excised surgically. In group 2, all the cysts were surgically removed. A ganglion with multiple cysts was confirmed on pathological examination. In group 3, the lesions were removed surgically; among the diagnoses were tendon sheath ganglion, giant-cell tumor of tendon sheath, neurilemmoma, and hemangioma. In group 4, no abnormal masses had appeared at follow-up examination. The 24 patients whose ganglions were treated by aspiration, as well as the 8 patients whose ganglions were excised, were monitored for more than 12 months. None of these 32 patients experienced residual pain or lesion recurrence. These results indicate that ultrasound is useful, in cases in which flexor tendon sheath ganglion are suspected, for assisting in diagnosis and determining whether patients should undergo aspiration or surgical excision.
 ...
PMID:Treatment of flexor tendon sheath ganglions using ultrasound imaging. 947 Oct 71

We present a patient with protracted hypertrophy of the left calf, light triceps suralis weakness, and mild inconstant left foot pain. The clinical picture evolved slowly throughout more than eight years, and lately slight weakness in anterior right leg musculature appeared. The magnetic resonance examination revealed the existence of an intrarachideal extraspinal tumor adjacent to the conus medullaris that histologically was a neurinoma. Although the neurogenic pseudohypertrophy has diverse etiology, the present association is unpublished.
 ...
PMID:[Muscular pseudohypertrophy and intraspinal neurinoma]. 947 Nov 66

Intratumoural bleeding into a trigeminal neurinoma is rare. The authors describe a case which had an apoplectic presentation with subsequent persistent unilateral ptosis, hemifacial pain and sensory loss. This proved to be due to a haemorrhage into a large trigeminal neurinoma.
 ...
PMID:Trigeminal neurinoma with an apoplectic onset. 947 76

A rare case of malignant schwannoma is described. The patient's main presentation was that of pain. The patient had no other symptom, particularly that related to the space-occupying lesion in the skull base that also was filling the pterygoid space. A 5-year cure was achieved by combined therapy of radiation and radical surgery. The rarity of these cases makes it impossible to do a comparative analysis including randomized clinical trials for outcome studies to find the optimal treatment for each patient.
 ...
PMID:Malignant epithelioid schwannoma of the mandible and the skull base. 948 85


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>