Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030193 (pain)
 261,466 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A comparison of the outcome of the treatment of fissure in ano by a lateral subcutaneous sphincterotomy (LSS) and by an anal dilatation (AD) has been made retrospectively through a questionnaire sent to patients who were operated upon between three months and five years beforehand. The questionnaire was completed by 86 patients who underwent the LSS, and 74 patients who underwent the AD. The two groups were comparable in age, but there were slightly more males in the LSS group. The results appear to favour the LSS, the patients in this group recording a recurrence of pain and problems of incontinence significantly less often than those in the AD group.
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PMID:Comparison of lateral subcutaneous sphincterotomy with anal dilatation in the treatment of fissure in ano. 52 73

When we die, it is only very rarely that we do so without days, weeks, or months of illness in which the suffering may be very great, sometimes from pain, often from breathlessness, impairment of consciousness, depression, anxiety, vomiting, bedsores, and incontinence. If we were able to choose our own time to die, there would be no need to suffer any of this. There should be a "right to die". It should be ethically and legally possible for the doctor attending a terminally ill patient, who asks him for help to take his own life, to put the means within his reach.
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PMID:Assisted suicide: some ethical considerations. 93 27

A case of chronic prostatitis where conventional chemotherapy and repeated transurethral resections failed to relieve pain is described. A cutaneous uretero-entero anastomosis was performed for troublesome pain and incontinence and only a permanent sympathetic block with phenol at the level of L4 achieved complete pain relief.
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PMID:Chemical sympathectomy with phenol for chronic prostatic pain. 97 80

One hundred and thirty-three subarachnoid phenol blocks were performed in 90 patients with intractable pain secondary to gynecologic cancer at the University of Iowa Hospitals in the period 1961 to 1975. Excellent to moderate pain relief was obtained in 77% of 117 evaluable blocks. Fifty-two percent of the blocks gave relief of over 1 months' duration and 27% over 2 months. Fourteen patients had a second contralateral block and 11 obtained 4 to 8 weeks' relief. Complications were temporary and occurred in 71% of the blocks, the most common being urinary and rectal incontinence. Subarachnoid phenol block is an effective method for relief of intractable pain; its use in gyneclogic oncology is discussed.
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PMID:Subarachnoid phenol block for pain relief in gynecologic malignancy. 98 20

Impact between the brain and the cristae of the base normally results as a consequence of inertia when an obstacle is hit, followed by contusion, or intra-, sub- or extradural haematoma. The skull itself may be briken (usually at the interpilasters or the weak points of the pilasters) or dented. Denting resulted in the depression of a circular fragments or fragments, with compression of the dura mater or brain; this, in turn, may be contused, lacerated or even crushed. Spinal crash fractures usually involve the lumbar region. Neck fractures are rare. The picture may be one of clinical silence (local pain) or marked neurological involvement. Damage to the cord is expressed in the form of shock, complete flaccid para- or tetraplegia, complete loss of sensation below the lesion, loss of deep and superficial reflexes, urinary retention and rectal incontinence. Treatment is rendered complicated by profuse scalp haemorrhages, respiratory insufficiency requiring orotracheal intubation and assisted respiration, convulsions, which should be handled with care, since ordinary anti-epilepsy products may mask the onset of hypertension and haematoma. Swelling should be reduced with cortisones. Diuretics may be too brusque and lead to intracerebral haematoma. In the case of spinal injuries, particular care should be excercised in shifting the patient and conveying him to hospital. Where high neck lesions are suspected, the possibility of damage to the originating segments of the phrenic nerve must be borne in mind.
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PMID:[Aeromedical problems in cranio-vertebral injuries]. 112 65

Lateral sphincterotomy is probably the operation of choice for most cases of intractable anal fissure in children. The lower half of the sphincter is divided in the left or right lateral position through a small external incision at the anal verge. An incision in the anal canal itself is avoided, postoperative pain is minimal and the risk of secondary hemorrhage is eliminated. The operation can be done as an outpatient procedure. Only one patient developed minor anal incontinence.
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PMID:Lateral subcutaneous internal sphincterotomy for anal fissure. Technic and experience with 22 cases in children. 112 73

A series of 90 patients with intussusception of the rectum (internal procidentia) has been studied. In 11 per cent of the patients there was also an enterocele and in 3 per cent, a large proctocele. Forty patients were operated upon by the Ripstein procedure. Indications for operation were, in most cases, incontinence for gas and/or feces. Seventy-five per cent of the preoperatively incontinent patients were, at follow-up 2 to 10 years after operation, continent. When indications for surgery were pain and or a sensation of obstruction, the results were poor; most of these patients had unchanged symptoms postoperatively, and some even had increased symptoms. There was one postoperative death. Of 50 patients treated conservatively during a period of 2 to 10 years, only two had to be operated upon: one due to the development of a rectal prolapse and the other due to severe pain and an increased sensation of obstruction.
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PMID:Intussusception of the rectum-internal procidentia: treatment and results in 90 patients. 114 81

The urogenital tuberculosis has undergone a change in form and clinical assessment. The absolute proportion of urogenital tuberculosis cases has fallen off sharply since 1967. The nmber of surgical interventions is also remarkably reduced. The cases exhibiting a milder stage have significantly increased, while the severe cases have decreased. This change of tuberculosis has made a conservative therapy favorable; therefore the current operative indication is somewhat different than 15 years ago. The time of release from the stationary treatment depends first on the animal experiment and bacterial findings; furthermore, tests are necessary to determine the status of immunity. It was revealed with urogenital tuberculosis, through regular examination of the menstrual blood of women, that the number of positive cases among women was considerably higher, than among men. In contracted bladder a surgical intervention is often necessary due to intense pain and incontinence. We prefer the rectal bladder with sigmoid pull-through inside the sphincter ani, whereby excellent success can be achieved. The study shows that the clinical assessment of tuberculosis is somewhat different today than is was earlier. Tuberculosis underwent a change in form that must be taken into consideration with respect to operative indication.
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PMID:Recent changes in the assessment of urogenital tuberculosis. 120 3

Medical complications of female circumcision/genital mutilation were studied among 290 Somali women from Mogadishu aged 18-54 years. They were of mean age 22 years. 88% underwent excision and infibulation, 6.5% clitoridectomy, and 5.5% a Sunna procedure involving excision of the prepuce of the clitoris. 69% of the respondents were circumcised at home and 52% of them by an untrained person such as a traditional birth attendant. 39% of the interviewed women had experienced significant complications after the operation, most commonly hemorrhage, infection, or urinary retention. 37 women reported a late complication of circumcision including dermoid cyst at the site of the amputated clitoris, urinary problems such as pain at micturition, dribbling urine incontinence, and poor urinary flow. 40 women had experienced problems at the time of menarche and 10 were operated because of haematocolpos. There were 119 married and defibulated women among the study sample. 87% of these women had been defibulated by their husbands without the need of instruments. The remaining 27 were defibulated with the use of various instruments such as knives, razor blades, and scissors.
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PMID:The risk of medical complications after female circumcision. 128 27

A prospective randomised study compared anal dilatation (n = 37), posterior internal sphincterotomy (n = 21) and lateral sphincterotomy (n = 20) in the surgical treatment of chronic anal fissures in 78 consecutive patients. All the operations were performed under general anaesthesia using standard techniques. Anal dilatation relieved anal pain early (immediate relief in 57% of patients; the mean pain-days +/- SD of 3.2 +/- 5.4 days). Anal fissures after this operation healed in a mean time +/- SD of 20.3 +/- 12.5 days, coming in second place to lateral sphincterotomy. Anal dilatation was followed by insignificant wound infection but its main disadvantage was a high rate of post operative anal incontinence (in 24.3% of patients). Fissurectomy and posterior internal sphincterotomy was followed by the longest period of post operative anal pain (mean +/- SD of 32.4 +/- 10 days) as compared to the other two operations. It was the least favourable operation. Lateral sphincterotomy was followed by early relief of pain (immediate relief in 95% of patients). It was not followed by wound infection. It had the quickest healing time for the fissures (a mean +/- SD of 14.7 +/- 8.7 days). It was followed by anal incontinence in only one patient. In conclusion lateral sphincterotomy was the most favourable operation and it is perhaps the operation of choice to perform in patients with chronic anal fissures needing surgical treatment.
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PMID:Surgical treatment of chronic fissure-in-ano: a prospective randomised study. 129 16


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