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Query: UMLS:C0029713 (immaturity)
 4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The clinical and pathological details of a case of reno-facial dysplasia are presented and described. Hyperplasia and lamination of Bowman's membrane, corneal endothelial dystrophy with degenerative changes in the posterior stroma, hypoplasia of the retinal ganglion cell and nerve fibre layers, and severe changes in the retinal and iris blood vessels are believed to be pathognomonic ocular features of this syndrome, in addition to cataract and signs of immaturity. These findings are compared with the few descriptions of the syndrome previously published. The corneal damage is postulated to result indirectly from oligohydramnios which causes chronic compression of the globes and thus endothelial damage due to contact with the spherical cataracts. The pathological changes in the retinal and iris vessels are either genetically determined or the result of chronic hypoxia.
Klin Monbl Augenheilkd 1978 Sep
PMID:[Ocular findings in reno-facial dysplasia (Potter-syndrome) (author's transl)]. 10 56

Thirty normal children (aged 3--68 months) and 16 autistic children (aged 36--62 months) were recorded during nonmedicated sleep and data pertaining to rapid eye movements (REM) were measured during the first three REM periods of the night. When time of night from which data were gathered was held constant, normal children showed a significant relationship between age and the organization of eye movements into discrete bursts. When autistic children were compared to age-matched normal controls, they showed an immaturity in this phenomena, their results being similar to those found in children less than 18 months of age. Such an immaturity could result from dysfunction at a number of diverse levels and sites in the central nervous system.
J Autism Child Schizophr 1976 Sep
PMID:Rapid eye movement (REM) activity in normal and autistic children during REM sleep. 18 48

Tiny babies have the potential problem of hypoglycemia due to diminished hepatic glycogen stores, which can be potentiated by conditions frequently present in this birth weight group: asphyxia, cold stress, hypoxia, polycythemia. Despite the early administration of fluid and feeding, tiny babies are still at risk for developing hypoglycemia. Their immaturity, expressed by their limited ability to tolerate parenteral glucose infusions, puts them at risk for becoming hyperglycemic as well. Hence careful glucose administration and frequent monitoring of blood glucose are essential during the first several days after birth, in anticipation of hypoglycemia as well as hyperglycemia.
Clin Perinatol 1977 Sep
PMID:Perinatal glucose homeostasis: the unique character of hyperglycemia and hypoglycemia in infants of very low birth weight. 33 33

Trisomy 22 was confirmed in a 20-year-old ambulatory female. Growth and mental retardation plus various dysmorphic features of this syndrome are described and compared with a previous survey. Several interesting unreported findings such as sexual immaturity and gait are discussed in regard to the 22 trisomy syndrome.
Hum Genet 1978 Sep 19
PMID:Trisomy 22 in a 20-year-old female. 70 Jul 9

The psychological maturity, interpersonal, and marital attributes associated with the sexual pleasure and frustration of 59 married professional men, who had also been studied as adolescents, were examined by means of 10--12 hr of psychological tests, questionnaires, and interviews. The men's wives, closest friends, and colleagues also completed questionnaires about them. Masters and Johnson's hypothesis was confirmed that sexual pleasure is enhanced in psychologically mature and healthy men whose interpersonal relations are mature, whose relations with their spouses are marked by mutuality in fulfillment of each other's needs, and whose marriages are happy and satisfying. Increasing sexual frustration was associated, although not so consistently, with psychological unhealthiness, interpersonal immaturity, inadequate marital communication, and marital unhappiness. Degree of adult sexual pleasure and frustration was not reliably predicted by adolescent peraonality traits.
Arch Sex Behav 1978 Sep
PMID:Marital sexual enjoyment and frustration of professional men. 71 16

Testicular capillary blood flow (TCBF) was measured by the radioactive inert gas clearance technique throughout the reproductive life of young adult foxes and was related to the spermatogenic and androgenic activities of the testis. Mean (+/-S.E.M.) blood flow (ml min-1 g-1) was maximal in January in adults during the mating period (0-65 +/- 0-03), and in pubertal animals (0-62 +/- 0-04). At this time spermatozoa were observed in the testes of all animals, but testicular weight and circulating testosterone levels were lower in the pubescent foxes than in the adults. TCBF was minimal during immaturity (0-29 +/- 0-03) and during the resting period of the adult (0-12 +/- 0-01). These values were associated with a low testosterone level and with the multiplication of gonocytes in the young or with the seasonal very low spermatogenic activity in the adult. During the prepubertal period, TCBF slowly increased and was accompanied by testicular growth. In the adult, in September, TCBF rapidly increased without changes of testicular size and then slowly increased as the testes enlarged. High plasma testosterone concentrations occurred later. During the period of testicular regression, TCBF, testicular size, spermatogenic and androgenic activities decreased together.
J Reprod Fertil 1977 Sep
PMID:Relationship between testicular blood flow, testosterone secretion and spermatogenic activity in young and adult wild red foxes (Vulpes vulpes). 91 74

The distribution and excretion of the staphylococcal exfoliatin was investigated following in vivo administration of highly purified 125I-labelled exfoliatin fractions to adult and newborn mice. Adult mice excrete approximately one-third of a test dose by 3 hours as compared to a fifteenth of a test dose excreted by newborn mice. Accordingly, blood tracer radioactivity reaches a relatively higher peak and shows a slower decline in newborns than in adults. The urine of adult mice contains considerable biologically active exfoliating material. Both nephrectomized and carbon tetrachloride-poisoned adult mice injected with exfoliatin develop generalized exfoliation whereas comparable doses in untreated controls have no effect. On the other hand, subtotal hepatectomy, followed by injection of exfoliatin, does not lead to exfoliation. We conclude that renal immaturity is a critical factor responsible for the susceptibility of neonates to generalized staphylococcal scalded skin syndrome.
Br J Dermatol 1976 Sep
PMID:The fate of Staphylococcal exfoliatin in newborn and adult mice. 97 18

The importance of morphological immaturity of the lung in the development of the respiratory distress syndrome was investigated. Atelectatic lungs of newborns were maximally expanded with a mineral oil of low kinematic viscosity (Somentor 33) or 10% Formalin. With this method, surface active forces of peripheral air spaces should not impede expansion of the lungs. 27 lungs of neonates who died of respiratory distress syndrome and 10 lungs of neonates without primary respiratory problems were examined. Following maximal expansion of the lungs with the respiratory distress syndrome show a hypercellular densely cellular tissue of the pulmonary segments, much like glanduloid hyperplasia with small peripheral air spaces and long distances for diffusion of the respiratory gases. The lungs of newborns without respiratory distress syndromes are well alveolar following expansion and show an optimal morphology for gas diffusion. A lack of a surfactant should have significant consequences in small air spaces.
Geburtshilfe Frauenheilkd 1976 Sep
PMID:[Morphological investigation of the neonatal lung with respiratory distress syndrome which was maximally distended with Somentor 33 and formalin (author's transl)]. 98 53

A 4 year survey of a low socioeconomic prenatal population in a large outpatient clinic revealed an incidence of 4.4% gonorrhea by cervical culture. These patients who were culture-positive had a 7.6% perinatal mortality rate compared to a 3.0% perinatal mortality rate among culture-negative patients from the same clinic. The immaturity and prematurity rate was significantly higher in the culture-positive group as was the incidence of premature rupture of the membranes and prolonged premature rupture of membranes.
J Am Vener Dis Assoc 1976 Sep
PMID:Asymptomatic gonorrhea and pregnancy. 101 Jul 61

The authors explored the influence of young maternal age and parity upon pregnancy outcome in a cohort of almost 887 adolescents and mature women from Camden, New Jersey. Primigravid primiparas aged 12-15 years were compared with mature primigravid primiparas aged 18-29 years. Multiparas aged 19 years and younger were compared with multiparas aged 19-29. The young multiparas had their first pregnancy at age 12-15 years, while the older multiparas had their first pregnancy at age 18 years or older. After controlling for confounding factors, the younger primiparas were found to have a modest, statistically insignificant increase in preterm delivery. Low gynecologic age, however, contributed disproportionately to the risk of preterm delivery in the group, with risk decreasing with each year from menarche. Statistical interactions associated with increased risk among multiparas of small-for-gestational-age infants included interactions between young age and low pre-pregnancy body mass, young age and a prior low-birth-weight infant, and young age and a prior preterm delivery. Although chronologic age may not be a good predictor of pregnancy outcome, adolescents remain a high-risk group due to factors which are more common among them such as biologic immaturity, inadequate prenatal care, poverty, minority status, and low prepregnancy weight, and because factors associated with an early adolescent pregnancy, such as low gynecologic age, may continue to influence the outcome of subsequent pregnancies.
Ann Epidemiol 1992 Sep
PMID:Young maternal age and parity. Influences on pregnancy outcome. 134 27


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