Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0029713 (
immaturity
)
4,335
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Lymph nodes were examined from 41 cases of typical chronic lymphocytic leukemia (CLL). Degree of
immaturity
was graded as absent to minimal (Grade I), moderate (Grade II) and marked (Grade III). A moderate degree of
immaturity
was found in the lymph node in 14 of 41 cases even though the cells seen on the initial bone marrow and peripheral blood smears obtained from these patients were essentially all mature. The morphology of these nodes could be confused with poorly differentiated lymphocytic or mixed lymphocytic-
histiocytic lymphoma
in terms of the degree of
immaturity
present. A marked degree of
immaturity
present. A marked degree of
immaturity
was found in 5 cases; the morphology of these cases resembled
histiocytic lymphoma
. In the remaining 22 cases
immaturity
was essentially absent. The morphology of these cases was similar to that of diffuse well differentiated lymphocytic lymphoma. Our studies suggest that a moderate degree of
immaturity
in the lymph node of patients with CLL does not indicate that these patients will have a marked shortening of their survival.
...
PMID:The lymph node in chronic lymphocytic leukemia. 58 71
