Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029713 (immaturity)
4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Lymph nodes were examined from 41 cases of typical chronic lymphocytic leukemia (CLL). Degree of immaturity was graded as absent to minimal (Grade I), moderate (Grade II) and marked (Grade III). A moderate degree of immaturity was found in the lymph node in 14 of 41 cases even though the cells seen on the initial bone marrow and peripheral blood smears obtained from these patients were essentially all mature. The morphology of these nodes could be confused with poorly differentiated lymphocytic or mixed lymphocytic-histiocytic lymphoma in terms of the degree of immaturity present. A marked degree of immaturity present. A marked degree of immaturity was found in 5 cases; the morphology of these cases resembled histiocytic lymphoma. In the remaining 22 cases immaturity was essentially absent. The morphology of these cases was similar to that of diffuse well differentiated lymphocytic lymphoma. Our studies suggest that a moderate degree of immaturity in the lymph node of patients with CLL does not indicate that these patients will have a marked shortening of their survival.
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PMID:The lymph node in chronic lymphocytic leukemia. 58 71

Microtopography and cellular content of mesenteric lymph nodes were studied in children who were born from healthy mothers (group 1) and from mothers with nephropathy (group II) and chronic pyelonephritis (group III). Lymph nodes of newborns from mothers with chronic pyelonephritis develop much slower than in control children and that from mothers with nephropathy. Lymph nodes in group II children resemble those of control group in their structure but its cellular content does not correspond control values. Morphological immaturity of lymph nodes of children from mothers with pyelonephritis allows to relate them to risk group that acquire significant immunomodulating correction.
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PMID:[Mesenteric lymph nodes of newborn from mothers with kidney diseases]. 1153 42