Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029713 (immaturity)
 4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Contraception always interferes into the sexual life of the couple, modifying it in an emotional or psychological sense. In many cases sexual communication is improved because of contraception; in many cases it has a negative influence, caused mainly by the mental immaturity of the partners, by their emotional instability, or by their sociocultural background. Negative sexual side effects of contraception are usually caused, in the woman, by a conflict with the traditional image of the woman as mother, and by an unconscious desire of fertility; in the man they are usually caused by the long-accepted identification of sexual potency with reproductive ability, and by fears for the newly acquired freedom of the female partner. Positive or negative psychological effects of contraception vary, but not greatly, according to the method used. A sympathetic and experienced doctor can furnish good advice on the matter.
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PMID:[Interference of contraception in the sexual life of the couple]. 1226 23

This survey of attitudes toward contraception is taken from a document concerning psychological aspects of 233 women seeking pregnancy terminations. 87.12% had utilized a method of contraception at some time, of which 66.5% had used pills, 29.6% had used natural methods, 23.6% had used local methods, and 11.16% had used IUDs. 33.47% of the total sample had refused pills, in 83.65% of cases because of fears for health, and in the remainder because of infrequent intercourse, fears for unborn children, lack of information, belief that women shouldn't be responsible for contraception, or fear of forgetting. 64.38% of the women in the total sample had discontinued use of pills, about 2/3 of them for personal reasons such as nervousness, changes in the relationship, nausea, menstrual changes, frigidity, and depression, which are difficult to evaluate objectively. In most cases of termination of pill use for external reasons, the cause was opposition by the physician. Personality traits of the sample women which could impede responsible fertility control included passivity and inconsistency in 16.47%, dependency in 47.64%, and immaturity and poorly structured personality in 40.34%. Personality disorders among the latter included enjoyment of risk, impulsivity and lack of capacity to anticipate, emotional instability, and significant egocentrism and narcissism. 21.89% had depressive tendencies, 22.75% had sadomasochistic tendencies, and 28.33% had tendencies toward somatization, each of which is often correlated with unconscious choice. The unconscious elements are often more significant than the conscious and apparent motives. More effective contraception and a prevention of abortions might result from making women aware of their unconscious motivations.
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PMID:[Dependable fertility control: hazards and barriers (author's transl)]. 1233 50

Studies involving juvenile myoclonic epilepsy (JME) patients have demonstrated an elevated prevalence of cluster B personality disorders (PD) characterized as emotional instability, immaturity, unsteadiness, lack of discipline, and rapid mood changes. We aimed to verify a possible correlation between structural brain abnormalities in magnetic resonance image (MRI) and the PD in JME using voxel-based morphometry (VBM). Sixteen JME patients with cluster B PD, 38 JME patients without psychiatric disorders, and 30 healthy controls were submitted to a psychiatric evaluation through SCID I and II and to a MRI scan. Significant reduction in thalami and increase in mesiofrontal and frontobasal regions' volumes were observed mainly in JME patients with PD. Structural alterations of the orbitofrontal cortex (OFC), involved in regulation of mood reactivity, impulsivity, and social behavior, were also observed. This study supports the hypothesis of frontobasal involvement in the pathophysiology of cluster B PD related to JME.
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PMID:Personality traits related to juvenile myoclonic epilepsy: MRI reveals prefrontal abnormalities through a voxel-based morphometry study. 1930 59

Cluster B personality disorders (PD), characterized as emotional instability, immaturity, lack of discipline, and rapid mood changes, have been observed among patients with juvenile myoclonic epilepsy (JME) and have been associated with a worse seizure outcome. Proper understanding of the neurobiology of PD associated with JME could contribute to understanding the basis for earlier and more effective interventions. In the present study, volumetric and geometric features of cortical structure were assessed through an automated cortical surface reconstruction method aiming to verify possible structural cortical alterations among patients with JME. Twenty-two patients with JME with cluster B PD, 44 patients with JME without psychiatric disorders, and 23 healthy controls were submitted to a psychiatric evaluation through SCID I and SCID II and to an MRI scan. Significant cortical alterations in mesiofrontal and frontobasal regions, as well as in other limbic and paralimbic regions, were observed mainly in patients with JME with PD. The present study adds evidence to the hypothesis of frontal and limbic involvement in the pathophysiology of cluster B PD in JME, regions linked to mood and affective regulation, as well as to impulsivity and social behavior. Moreover, a multidimensional pattern of frontal, limbic, and paralimbic changes was observed through a method of structural analysis which offers different and simultaneous geometric features, allowing the elaboration of important pathophysiologic insights about cluster B PD in JME.
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PMID:Personality traits in juvenile myoclonic epilepsy: evidence of cortical abnormalities from a surface morphometry study. 2351 Jul 95

The best-established facts in relation to homosexuality point to developmental-psychological, not genetic or physiological, causation. The efforts of the last few decades to find evidence to support a biological theory have made it more doubtful than ever that such evidence will be found. In contrast, many studies have shown that the most significant factor which correlates with homosexuality is "gender nonconformity" or same-sex peer isolation. Another factor closely associated with homosexuality is an imbalance in parent-child interaction, notably forms of over-influence of the opposite-sex parent in combination with a deficient relationship with the same-sex parent. The third well-established correlation is with inherent, rather than discrimination-produced, "neuroticism" or emotional instability/immaturity. Structured around this pivotal evidence from statistical as well as clinical research, homosexuality is explained here as a character neurosis. Characteristics of this neurotic character syndrome include personality immaturity, self-victimization, and self-centeredness. This syndrome affects not only the emotional but also the moral and spiritual dimensions of the psyche and if indulged leads to generalized personality deterioration. Therapeutically, a holistic approach, simultaneously addressing the emotional, moral, and spiritual components of the psyche, offers the best opportunity for overcoming homosexuality. De-egocentrization and personality maturity, including the development of mature manhood/womanhood, are the goals of therapy.
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PMID:On the Psychogenesis of Homosexuality. 3008 52