Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029713 (immaturity)
 4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Prenatal ultrasound examination has radically changed physician's attitude toward hydronephrosis. Fetal hydronephrosis must be searched out and looked at with a wider vision than it was done in the past. A mechanical obstruction must be suspected indeed, but often we have to face a functional dilatation, caused by immaturity, which can clear up in uterus or which will simply require a careful follow-up during the post natal period. Vesicoureteral reflux may count for 10 to 33% of urinary tract dilatations. There are no pathological limit values clearly stated in literature: a pyelectasis can only be the expression of a normal anatomical variability, without features of disease. In creating a diagnostic protocol for the newborn with prenatal diagnosis of hydronephrosis, all these possibilities must be accounted for the risk of focusing on mechanical obstruction is to overestimate and over-treat children that will never obtain any benefit from a surgical procedure.
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PMID:[Diagnostic approach to newborns with prenatal diagnosis of hydronephrosis]. 1122 Oct 26