Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0029713 (immaturity)
 4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The prevalence of sexually transmitted disease (STD), pelvic inflammatory disease (PID), and cervical cancer, and the relation between these conditions were studied in 2111 Ethiopian women. Early sexual activity was associated with an increase in prevalence rates of STD and PID; possible aetiological factors include physical and immunological immaturity of the female genital tract and the number of sexual partners.
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PMID:First coitus before menarche and risk of sexually transmitted disease. 196 79

Although the majority of women experience no long-term significant psychopathology following an elective abortion, up to 5% exhibit severe psychiatric sequelae. Reported here is the case of a woman with an obsessive-compulsive disorder apparently related to abortions at ages 14 and 15 years of age. In her mid-20s, during her fourth marriage, the woman became convinced that she had been impregnated by a physician in the course of a pelvic exam and a proctosigmoidoscopy. At the time, she was obsessed that she would sabotage her marriage by becoming pregnant with a man other than her husband. The obsession later expanded to include a fear of contracting a sexually transmitted disease. In psychotherapy, the etiology of this disorder was linked to the patient's guilt and fear of punishment connected to her early abortions. The invasiveness of the sigmoidoscopy procedure triggered memories of these abortions and was subconsciously viewed as another pregnancy termination. A review of this woman's history revealed most of the factors considered to promote psychiatric problems after abortion, including young age, unmarried status, passivity, lack of social support, reservations about the abortions, parental pressure to abort, immaturity, and unstable relationships with the fathers. Counseling before and after abortion for women identified as having risk factors for emotional problems is recommended.
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PMID:Obsessive-compulsive disorder apparently related to abortion. 275 Oct 12

From April-September 1986, researchers asked all 14-19 year old females attending the University of California at San Francisco's Teen Colposcopy Clinic to take part in an epidemiologic study of risk factors for cervical intraepithelial neoplasia (CIN). The 4 comparison groups consisted of a CIN group, a high risk group (external warts or abnormal Pap smear, no CIN, similar behavioral risk factors as CIN group), as asymptomatic group, and a symptomatic group (negative Pap smears and lower genital tract infection complaints). The CIN group was more likely to smoke or have smoked than the asymptomatic and symptomatic groups (p.01) and to use oral contraceptives than the asymptomatic group (p.02). In addition, patients with CIN had more lifetime sexual partners than did the asymptomatic group (p.001). The teens in the CIN group reached menarche on average 1 year later than did those in any of the comparison groups (p.05). This also had a greater area of ectopy than the other 3 groups (p.02). External genital warts occurred more often in the CIN group than in either the asymptomatic or symptomatic groups (p.001). Further, the CIN and high risk groups were more likely to have had any sexually transmitted disease than the asymptomatic (p.001) or symptomatic (p.01) groups. In addition, chlamydiosis occurred more often in the CIN group than in the asymptomatic (p.001) or symptomatic groups (p.03). The results indicate that cervical biologic immaturity may play an important role in development of CIN in adolescents. They also showed that CIN patients had more ectopy than the others thereby demonstrating that cervical biologic immaturity may rend the epithelium vulnerable to human papilloma virus invasion and neoplastic change.
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PMID:Differences in biologic maturation, sexual behavior, and sexually transmitted disease between adolescents with and without cervical intraepithelial neoplasia. 276 12

2 outcomes of the high level of unprotected sexual activity among US adolescents--teenage pregnancy and infection with sexually transmitted diseases (STDs) and human immunodeficiency virus (HIV)--are produced by similar behavioral factors. Among these are an unwillingness to acknowledge in advance sexual activity, a failure to seek out necessary preventive knowledge, an unwillingness to engage in preventive behaviors such as use of condoms or other contraceptives, and a lack of communication about sexuality in adolescent relationships. Despite this overlap, health educators and service providers have failed to develop an integrated approach for dealing with adolescent pregnancy and STD/HIV risk. Proposed is a sequence of preventive behaviors and skills to be taught to teenagers, including acceptance of their sexuality, education regarding sex-related preventive options, an active commitment to engage in preventive behaviors, the negotiation of sex-related prevention with one's partner, performance of public preventive acts such as condom purchase, consistent practice and reinforcement of preventive behaviors, and the ability to shift preventive "scripts." At the same time, programs must address the potential psychological obstacles to the performance of sex-related preventive behaviors--e.g., negative feeling about sexuality, misinformation coupled with cognitive immaturity, and mass media images and fantasies. Program interventions can be delivered most efficiently through the public school system, with linkages to birth control clinics, STD clinics, HIV testing centers, and drug treatment programs. The type of sexuality education proposed--provision of relevant information that teenagers can actively translate into preventive behaviors--should be anticipated to produce more resistance from conservative community forces than traditional educational efforts.
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PMID:All together now. An integrated approach to preventing adolescent pregnancy and STD/HIV infection. 1228 59

This study analyzes the concepts displayed by rural men in the Zona da Mata region in the State of Pernambuco, Brazil, concerning their sexual practices and STD/AIDS prevention. The study adopts a qualitative methodology, having interviewed 22 men According to the interviews, their first sexual intercourse is characterized as a learning experience and is sometimes marked by violence. They make a distinction between the "woman at home" and "street women"; they acknowledge women's sexual desire and value reciprocity in sexual relations, differentiating between the kinds of sex they have with different categories of women. Seven men report homoerotic experiences during adolescence, which they ascribe to immaturity, not affecting their heterosexual identity. Condom use, perceived in a negative light, is inconstant and irregular, inversely proportional to knowing the female partner. STDs in general inspire little fear, while AIDS is associated with death; the interviewees do not see themselves at risk of acquiring HIV. Ambiguities in the men's discourse, together with a basically ineffective approach by health services and preventive campaigns, reveal a high level of exposure to the risk of contracting STDs/AIDS among the interviewees and their female or male partners.
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PMID:[Sexuality and STD/AIDS prevention: social representations by rural men in a county in the Zona da Mata region in Pernambuco, Brazil]. 1502 62