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Query: UMLS:C0029713 (immaturity)
 4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tiny babies have the potential problem of hypoglycemia due to diminished hepatic glycogen stores, which can be potentiated by conditions frequently present in this birth weight group: asphyxia, cold stress, hypoxia, polycythemia. Despite the early administration of fluid and feeding, tiny babies are still at risk for developing hypoglycemia. Their immaturity, expressed by their limited ability to tolerate parenteral glucose infusions, puts them at risk for becoming hyperglycemic as well. Hence careful glucose administration and frequent monitoring of blood glucose are essential during the first several days after birth, in anticipation of hypoglycemia as well as hyperglycemia.
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PMID:Perinatal glucose homeostasis: the unique character of hyperglycemia and hypoglycemia in infants of very low birth weight. 33 33

A retrospective case-control study of necrotizing enterocolitis (NEC) was conducted among infants weighing greater than 2,000 g at birth. Twenty-three infants met the NEC criteria for inclusion in the study; 12 weighed 2,001 to 2,500 g at birth and 11 weighed greater than 2,500 g at birth. Hypoglycemia occurred in 7/12 (55%) infants weighing 2,001 to 2,500 g and in 4/35 (11%) control subjects (P less than .02). In infants weighing greater than 2,500 g at birth, polycythemia (occurring in 7/12 study infants (58%) and 5/32 (16%) control infants) and respiratory distress (3/11 study infants (27%) and 0 control subjects) were significantly associated with NEC (P less than .02). Larger infants with a history of perinatal stress and/or physiologic immaturity are likely to be at greater risk for NEC than their normal counterparts.
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PMID:Risk factors for necrotizing enterocolitis in infants weighing more than 2,000 grams at birth: a case-control study. 684 74

Upper extremity arterial injuries in preterm infants are usually of iatrogenic origin. Current microsurgical techniques permit extremity revascularization in these patients. The authors report the microsurgical repair of a 0.7-mm brachial artery in a 940-g preterm infant. The preterm infant warrants special consideration due to physiological immaturity. Rapid fluid shifts, a relative polycythemia, and the potential for low cardiac output states increase the risk for vascular thrombosis. Systemic heparinization is contraindicated in this population due to the risk of intraventricular hemorrhage. Optimization of various physiological variables should reduce the risk of thrombosis.
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PMID:Revascularization of the upper extremity in a preterm infant: a case report and review of the literature. 1059 27